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GlossaryMelatonin Receptors

proteins that bind melatonin to regulate sleep and other functions

Melatonin receptors are proteins found in various parts of the body, including the brain and skin, that bind to the hormone melatonin. These receptors help regulate sleep-wake cycles, mood, and even hair growth by influencing cellular activities in response to melatonin.

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community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 1 year ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Does melatonin dissolve in isopropyl alcohol

in Technology 8 upvotes 1 year ago

The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

community Is anyone using melatonin for hair loss?

in Research/Science 9 upvotes 4 months ago

Melatonin is being discussed as a potential treatment for hair loss, with questions about its effectiveness and whether it should be used topically or orally. No specific conclusions or personal experiences were shared.

community Melatonin options for Europe??? Retrograde Alopecia

in Product 3 upvotes 6 months ago

A user is considering using melatonin for hair recovery on the side and neck area but is unsure about the best options in Europe and whether a dietary supplement form can be applied to the scalp. They found a product but are hesitant and seeking opinions on its use for alopecia.

community Optimal dose for topical Melatonin

in Treatment 6 upvotes 1 year ago

The conversation is about finding the optimal concentration of topical melatonin for hair loss treatment. The user is considering making their own solution and is unsure whether a higher concentration is more effective for deactivating prolactin receptors.

community Melatonin and hair growth: legit or scam?

in Research/Science 8 upvotes 1 year ago

Melatonin may improve hair growth rate and thickness. The user is seeking input on the legitimacy of this claim.

community Compounding Topical Melatonin at Home

in Treatment 6 upvotes 2 years ago

Melatonin at a 0.0033% concentration shows results for hair loss when used topically. A user is discussing how to replicate this by adding 2mg of Melatonin to 60ml of Minoxidil solution.

community Melatonin a possible tool to help fight AGA hair loss.

in Research/Science 52 upvotes 3 years ago

Topical melatonin may help reduce hair loss and increase hair thickness in people with androgenetic alopecia (AGA), with some studies showing positive results. It can be mixed with minoxidil for application, and its effectiveness might be enhanced when used with micro-needling, but results may vary among individuals.

community What melatonin product are you using? Are you making your own solution?

in Product 3 upvotes 1 month ago

The conversation is about using melatonin for hair loss, with users discussing different products and methods for topical application. They mention concerns about ingredients and cost, and one user suggests a magnesium scalp serum with melatonin.

community Topical Melatonin for mild aga

in Chat 2 upvotes 8 months ago

The conversation is about an 18-year-old male considering topical finasteride for hair loss and asking about the effectiveness of topical melatonin for hair regrowth and density. No specific treatments were confirmed to be used.

community How do you incorporate topical melatonin into your routine?

in Research/Science 12 upvotes 9 months ago

Topical melatonin may have positive effects on hair loss by keeping hair in the growing phase. Users are discussing product recommendations and DIY methods for incorporating melatonin into their hair care routine.

community Reminder to add melatonin to your topical solutions (or to min alone if that’s the only topical you take)

in Treatment 3 upvotes 11 months ago

Adding melatonin to topical hair loss treatments like Minoxidil can promote thicker hair growth, with the only side effect potentially being improved sleep. Melatonin is affordable and easy to mix into solutions.

community Reminder to add melatonin to your topical solutions (or to min if you take fin orally)

in Treatment 3 upvotes 11 months ago

Adding melatonin to minoxidil can improve hair growth and thickness, and it's easy to use with minimal side effects. The recommended concentration for melatonin in the solution is between 0.05% and 0.2%.

community Diluting Melatonin Sublingual Spray

in Treatment 2 upvotes 1 year ago

A user wants to dilute a melatonin sublingual spray to 0.0033% for use as a topical hair loss treatment. They ask if distilled water can be used for dilution and how much is needed for stability over months.

community Topical melatonin instead of fin

in Research/Science 9 upvotes 1 year ago

A 22-year-old man has been using topical melatonin for a year to slow hair loss and it appears to be effective. He's seeking alternatives to finasteride due to potential side effects, and is interested in understanding how melatonin works to prevent hair shedding.

community Topical Melatonin, Hair Loss/Growth, and Seb Derm (Seborrheic Dermatitis)

in Research/Science 13 upvotes 1 year ago

Topical melatonin was found to significantly increase hair density and decrease scalp conditions like seborrheic dermatitis. The user is considering using it alongside finasteride and oral minoxidil for treating hair loss and scalp health.

community Topical melatonin/cetirizine instructions

in Treatment 16 upvotes 1 year ago

User shares a topical hair loss solution using melatonin and cetirizine to help reduce shedding and itching. Instructions provided for creating and using the mixture, with additional lifestyle tips for overall hair health.

community Topical melatonin/oral

in Research/Science 12 upvotes 3 years ago

The conversation discusses the potential positive effects of melatonin on hair growth. The original poster plans to try both oral and topical melatonin and is seeking recommendations for a good source.

community Tropical Melatonin??

in Product 7 upvotes 3 years ago

The conversation is about the effectiveness of topical melatonin for hair loss. No specific treatments were discussed, only a sarcastic suggestion to go to tropical places and eat coconuts.

community Have you guys heard about topical melatonin?

in Research 7 upvotes 4 years ago

Topical melatonin may improve hair density and thickness, and reduce hair loss and seborrhea with no significant side effects. The user made their own melatonin solution for hair treatment.

community Anyone tried topical melatonin?

in Treatment 4 upvotes 2 months ago

The conversation is about using topical melatonin for hair retention and its potential effectiveness alongside minoxidil. The user explicitly does not want advice about finasteride.

community Finasteride + topical melatonin + rosemary oil for regrowth

in Treatment 1 upvotes 4 months ago

The user has been using finasteride for 4 months with positive results, including thicker and darker hair. They are seeking advice on maximizing hair growth without minoxidil, using a routine that includes finasteride, rosemary oil, argan oil, topical melatonin, specialized shampoos, and vitamins.

community Anybody using topical melatonin or zix in 2024?

in Chat 12 upvotes 5 months ago

The conversation is about using topical melatonin or zix for hair loss without affecting hormones. The user is seeking advice on which treatment is more effective.

community Can I crush caffeine/melatonin tablets and add them to my minoxidil?

in Treatment 4 upvotes 5 months ago

A user asked if they can crush caffeine and melatonin tablets to add to their minoxidil solution. Another user sarcastically suggested adding rat poison.

community best way make topical melatonin solution

in Treatment 8 upvotes 5 months ago

A user wants to try melatonin for hair loss by mixing melatonin powder with a topical oil serum. They are asking if this mixture is possible and effective.

community How to make topical melatonin?

in Treatment 1 upvotes 7 months ago

The conversation is about creating a topical melatonin treatment for hair loss. Specific treatments discussed include Minoxidil, Finasteride, and RU58841.

community People who taking melatonin, do you have any grey hairs?

in Research/Science 8 upvotes 1 year ago

The post discusses the theory that melatonin could reverse grey hair by regulating certain enzymes. However, users who have taken melatonin reported no effect on preventing or reversing grey hair.

community Okay to add melatonin powder to the topical finasteride solution?

in Finasteride/Dutasteride 15 upvotes 1 year ago

The conversation discusses adding melatonin powder to a topical finasteride solution for hair loss, with one reply suggesting that melatonin may promote faster hair growth but advising against mixing it directly into the solution due to potential instability.

community Doctor Summarizing Melatonin Research for Hairloss

in Research/Science 9 upvotes 1 year ago

The conversation is about the use of melatonin for hair loss. Specific treatments discussed are not provided in the text.

community Anybody using topical melatonin in your stack? How is it working?

in Minoxidil 8 upvotes 1 year ago

The conversation discusses using topical melatonin as a treatment for hair loss, with one person considering adding it to their minoxidil solution and another sharing their experience of no hair shedding, possibly due to melatonin.