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Did you mean Lipid Accumulation?

GlossaryLipid Accumulation

excessive fat build-up within cells or tissues

Lipid accumulation, also known as fat accumulation, refers to the build-up of lipids (fats) within cells or tissues. This process can occur in various parts of the body, including the liver, muscles, and skin, and is often associated with metabolic disorders such as obesity, diabetes, and cardiovascular diseases. In the context of hair and alopecia, excessive lipid accumulation in the scalp can potentially disrupt normal hair follicle function, contributing to hair loss.

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community Efficacy of different dutasteride doses vs finasteride

Previous_Advertising in Research/Science 123 upvotes 1 year ago

Dutasteride doses matter for hair loss treatment and are more effective than finasteride. RU58841 is suggested for better gains, but side effect profiles should be considered.

community A warning to those thinking about using Dutasteride

y3pkm8 in Finasteride/Dutasteride 99 upvotes 4 years ago

The potential risks of long-term use of Dutasteride and how it may be linked to elevated liver enzymes, cholesterol levels, and decreased testosterone. Alternative treatments such as Finasteride and RU58841 were also discussed.

community Having androgen receptor density and sensitivity at wrong f*ing place

False_Fuel9435 in Satire 7 upvotes 3 months ago

The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

community to all people who cannot tolerate anti androgens (loe dose topical fin, pyrilutamide, CB) i am getting desperate, looking for a solution

Additional_Rough_968 in Research/Science 13 upvotes 2 years ago

The user tried Minoxidil without success, and Finasteride worked but caused sexual side effects even at a very low dose. They are seeking alternative treatments for hair loss as they cannot tolerate anti-androgens and are also in therapy for mental health.

community New and Interesting HairLoss Studies/Papers/Reviews

TerpsandCaicos in Treatment 41 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Interesting article links major MPB theories to western diet (and life-style)

patrickular in Research/Science 58 upvotes 2 months ago

Poor diet and lifestyle contribute to male pattern baldness. Treatments like Minoxidil, dietary changes, and lifestyle adjustments may help slow hair loss.

community So does oral minoxidil age your skin or not

Simple_Bass_5869 in Minoxidil 41 upvotes 10 months ago

Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

nkrata in Research 830 upvotes 6 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community A warning to those using or thinking about using Dutasteride – Follow-up

y3pkm8 in Finasteride/Dutasteride 18 upvotes 3 years ago

The post and conversation are about the long-term side effects of using Dutasteride and Finasteride for hair loss, including issues like raised liver enzymes, high cholesterol, and loss of libido. The user advises regular blood work and careful monitoring for those using these treatments.

community Is 2-deoxy-D-ribose (2dDR) good for human hair?

Paulative in Research/Science 9 upvotes 5 months ago

Topical 2-deoxy-D-ribose (2dDR) regrows hair in mice almost as well as 2% Minoxidil. However, 2dDR may contribute to oxidative stress and hair loss due to the formation of advanced glycation end products (AGEs).

community Does melatonin dissolve in isopropyl alcohol

newguyhere245 in Technology 8 upvotes 1 year ago

The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

community Anyone experienced weight gain on dutasteride?

Tyxoti in Finasteride/Dutasteride 6 upvotes 2 years ago

Dutasteride can lead to increased cholesterol and liver fat. The user is reconsidering its use due to high cholesterol and lipid levels despite a healthy lifestyle.

community The Worst Hair Loss Condition You (MAY) have: LPP

noeyys in Research/Science 43 upvotes 5 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Minoxidil Finasteride heart problems

Sea-Way3636 in Update 97 upvotes 9 months ago

A user experienced heart problems after taking 1mg finasteride and 2.5mg oral minoxidil and is considering quitting minoxidil. Others discussed their experiences with heart issues and minoxidil, with some suggesting topical minoxidil as a safer alternative.

community C’est terrible - at my wits end

Desperate-War-3925 in Female 447 upvotes 1 year ago

A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

community Soon nearly 2 Years Finasteride+Minoxidil Update

easymoneysniper31 in Progress Pictures 406 upvotes 1 year ago

The conversation is about a user sharing a nearly 2-year update on hair regrowth using finasteride and minoxidil, with occasional use of microneedling. Commenters are impressed with the significant improvement in the user's hair.

community Late responders on finasteride alone

_-Watermelon-_ in Treatment 16 upvotes 11 months ago

The conversation is about someone who has not seen hair regrowth after 6 months on finasteride alone, asking if others have experienced delayed results. Some responses indicate that results can sometimes be seen after 12 months, with full effects up to 24 months.

community How does dutasteride regrowth work?

nobodyputsbabyinthe in Finasteride/Dutasteride 6 upvotes 8 months ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

community My hair thinning after Accutane and B12 deficiency. Using minoxidil.

Anxious-Author-104 in Minoxidil 2 upvotes 1 year ago

A user experienced hair thinning after taking Accutane and having a B12 deficiency. They are currently using minoxidil and beclomethasone dipropionate lotion for treatment.

community Loosing hope after not seeing improvement in hair regrowth.

Melodic_Parfait4697 in Minoxidil 7 upvotes 1 year ago

A 22-year-old male is not seeing hair regrowth after using minoxidil and finasteride for a year and additional treatments for three months. Suggestions include improving scalp absorption with sea salt and trying a lipid-based solution, microneedling, and possibly switching to dutasteride if no improvement after 1-2 years.

community [25, F] [RANT] Shedding since March 2020. This just isn’t fair.

missbloombastic in Female 42 upvotes 3 years ago

User "missbloombastic" has been experiencing hair loss since 2016 and tried min, fin, multivitamins, and spiro with mixed results. Another user shares their struggle with hair loss and its impact on self-esteem, while a third user suggests checking blood tests and confirming the cause of hair loss.

community Physio-metabolic method (antiandrogen, minoxidil, leg training and cold)

MagicBold in Treatments 309 upvotes 8 months ago

The method combines finasteride, minoxidil, intense leg exercises, and cold exposure to treat androgenetic alopecia. It aims to boost metabolism and reduce androgenic effects, enhancing hair growth.

community 26, i was cool w shaving bald but I wanted to hold on for a little longer. Just topical min and rosemary shampoo.

DrGinkgo in Progress Pictures 688 upvotes 1 year ago

The post and conversation are about a user's successful regrowth of hair using topical minoxidil and rosemary shampoo. Other users discuss the potential limitations of minoxidil and recommend using finasteride to maintain hair growth.

community Lion Mane Part 2: Microneedling with Topicals, beneficial compounds, maybe?

L3onidas-Kelevra in Microneedling 1 upvotes 8 months ago

The conversation discusses microneedling techniques and the use of Minoxidil, copper peptides, EGF, FGF, ceramides, and hydration serums to enhance hair growth. It explores optimizing scalp conditions and the potential benefits of various compounds in conjunction with microneedling.

community Stop expecting results in 2 months!

TheFuckNameYouWant in Treatment 125 upvotes 9 months ago

People discussing hair loss treatments emphasize the need for patience, as results from using finasteride and minoxidil can take 8-12 months or longer. Some users report early signs of improvement, while others experience continued shedding or slower progress.

community How much would a high dose dutasteride scalp dht inhibition be?

Traditional_Run_6940 in Finasteride/Dutasteride 10 upvotes 9 months ago

The conversation discusses the potential for high doses of dutasteride to completely inhibit scalp DHT and speculates whether this could cure baldness when combined with a topical antiandrogen. Specific dosages mentioned are 0.5 mg reducing scalp DHT by 55% and 2.5 mg by about 79%.

community The theory that explains everything. The malloclusion theory has been proven.

joaopassos4444 in Research/Science 27 upvotes 1 year ago

Brian Dye's theory links skeletal malocclusion type II to hair loss, suggesting it's a blood flow issue. Treatments mentioned include minoxidil, finasteride, and anti-inflammatory drugs like benaxoprofen.

community Dutasteride at 21 years old. Is it safe?

Key-Painter-9194 in Finasteride/Dutasteride 12 upvotes 1 year ago

A 21-year-old individual questioning the safety and potential side effects of using Dutasteride for hair loss, after Finasteride and RU58841 had limited effect. The responses vary, with some users suggesting it's safe and others advising to check hormone levels before proceeding.

community Has anyone tried the New Nordic Hair Gro tablets?

guitarloverme in Product 2 upvotes 1 year ago

The conversation discusses the effectiveness of New Nordic Hair Gro tablets for hair loss. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

community Give finasteride time to work!

PS4Dreams in Progress Pictures 298 upvotes 8 months ago

A user shared their 2-year experience with finasteride for hair loss, noting initial success, a period of shedding, and eventual improvement. Another user mentioned seeing no improvement until 14 months in, emphasizing the need for patience.