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      community Jxl069 (pp405 api) week 8 update

       205 upvotes 1 year ago
      The user shared minimal results from using JXL-069 for hair loss, noting a slight lengthening of vellus hairs and plans to switch to a prodrug variant due to limited effectiveness. They also mentioned using finasteride and minoxidil, which have plateaued in results.

      community Almost 10 months into dut/oral min and it’s getting worse (with pics)

       132 upvotes 1 month ago
      A user switched from finasteride and topical minoxidil to dutasteride and oral minoxidil, but experienced worsening hair loss and thinning. Suggestions included returning to finasteride, adding finasteride to the current regimen, or considering other factors like genetics or additional causes of hair loss.

      community Almost 6 months on Oral fin and Oral Min HAIRLINE

       189 upvotes 1 month ago
      The user experienced significant hairline improvement after almost six months using 1.25mg oral finasteride daily, 5mg oral minoxidil, and ketoconazole shampoo weekly, with side effects including increased body hair growth. They plan to switch to dutasteride and finasteride, and have stopped using a dermastamp due to irritation.

      community rudirect ru58841 seems bunk to me

      in Treatment  6 upvotes 4 months ago
      RU58841 from rudirect caused more hair shedding and itch, while anageninc's RU58841 improved the situation. Users are concerned about the quality and authenticity of RU58841 from different suppliers, including those from China.

      community Yet another hrt update (4 months estradiol and spiro + > 4 years of fin and min) (you should absolutely not take estradiol and spiro if you look manly and want to continue to look manly)

       4 upvotes 1 year ago
      The conversation discusses hair loss treatments, including finasteride, minoxidil, estradiol, and spironolactone, with a focus on their effects on hair regrowth and gender transition. The original poster shares their personal experience with these treatments, emphasizing that estradiol and spironolactone should not be used by those who want to maintain a masculine appearance.

      community UPDATE - 7 months 2,5 dutatesteride

       10 upvotes 1 year ago
      The user continues to experience hair loss despite using dutasteride 2.5mg, minoxidil 5mg, and ciclopirox shampoo, and plans to reassess after one year. Others report similar issues with dutasteride, with some switching to finasteride or adding RU58841.

      community No Visual Change But I Feel Like My Hair is Stronger

       13 upvotes 1 year ago
      The user feels their hair is stronger despite no visual change after using Finasteride for 9 months and Minoxidil for 7 months, and plans to add microneedling. Other users share similar experiences, suggesting combinations like Finasteride with Dutasteride and Minoxidil with Tretinoin for better results.

      community 1.2 mg fin/3 mg min + 4 month update. How we lookin?

       30 upvotes 1 week ago
      The user reported using 1.2 mg finasteride and 3 mg minoxidil, experiencing initial shedding and increased hair growth on knuckles, arms, and forehead. They did not notice any significant side effects.

      community Inhibition of collagen synthesis, oral versus topical minoxidil

       4 upvotes 3 years ago
      The conversation discusses the use of oral versus topical minoxidil for hairline recession, with concerns about collagen synthesis inhibition. Oral minoxidil may affect collagen production more broadly, while topical minoxidil's effects are localized but may cause skin issues.

      community Norwood 7 wants some hair. 5 months on oral fin/min

      in Progress Pictures  8 upvotes 1 year ago
      A user experienced heart palpitations and breathing issues while using oral finasteride and minoxidil for hair loss and plans to switch to generic finasteride and topical minoxidil. They also use Nizoral shampoo and are considering a moisturizing shampoo due to dryness and itchiness.

      community September - december with fin + oral & topical min + ru58841.

       165 upvotes 1 year ago
      The user experienced hair regrowth using finasteride, oral and topical minoxidil, and RU58841, despite initial shedding. They also transitioned from finasteride to dutasteride and addressed scalp issues with a folliculitis shampoo.

      community 1mg of finasteride/2 sessions of Kenalog injections/ Clobetasol (4 months into treatment)

       5 upvotes 2 months ago
      The user is undergoing treatment for hair loss using finasteride, Kenalog injections, and Clobetasol, along with vitamin D and collagen supplements. They are considering additional treatments like minoxidil and microneedling, and there is discussion about whether the hair loss is due to stress, alopecia areata, or a scarring condition like lichen planopilaris.

      community Oral Minoxidil Secret Very important

      in Minoxidil  237 upvotes 1 year ago
      Oral minoxidil can cause side effects like shortness of breath and constipation, which may be reduced by taking it in the morning. Some users experience no side effects, while others switch to topical treatments or adjust their dosage and timing to manage symptoms.

      community Alfatradiol 1% study rebuttal.

       4 upvotes 3 years ago
      Alfatradiol is often discussed at a 1% concentration, but studies typically use 0.025%. Some users report success using it as a topical treatment alongside other hair loss treatments like finasteride.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

       3 upvotes 1 year ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community Finasteride solution changing colors

      in Finasteride/Dutasteride  1 upvotes 5 months ago
      A user noticed a color change in their hair loss solution containing minoxidil, finasteride, retinoic acid, and hydrocortisone after storing it for several months. They are concerned about the effectiveness of the solution due to potential oxidation.

      community Five months of Dut brings in the corners😌

      in Update  63 upvotes 1 year ago
      The user switched from finasteride to dutasteride due to side effects and hair thinning, and experienced thicker hair with no side effects after five months. The conversation includes positive feedback and questions about the transition process.

      community Switching to oral minoxidil...

      in Minoxidil  3 upvotes 5 months ago
      OP plans to switch from topical to oral minoxidil due to limited results and is advised to overlap both for a few weeks before discontinuing the topical. Oral minoxidil may be more effective for non-responders to topical treatment.

      community 5 Month Update. Topical RU58841 & Minox

       11 upvotes 4 months ago
      The conversation discusses hair regrowth using topical RU58841 and Minoxidil. Users suggest adding finasteride or dutasteride for better long-term results.

      community Hydrocortisone helps with itch

       4 upvotes 9 years ago
      Hydrocortisone helps relieve scalp itchiness, possibly caused by minoxidil. Users discuss its effectiveness for managing this side effect.

      community DHT levels went up after 6 months of finasteride usage.

       22 upvotes 2 weeks ago
      Finasteride's effectiveness may be reduced due to heat exposure, affecting DHT levels. Testing methods and medication storage conditions are likely factors in the unchanged DHT levels.

      community EMA is re-examining Winlevi (clascoterone at lower concentration)

       8 upvotes 1 year ago
      Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

      community What has the evidence been on side effects with CB?

       4 upvotes 6 years ago
      Clascoterone (CB) shows an excellent safety profile with no serious side effects, but its effectiveness may decline after six months, making it more suitable as an adjunct treatment with finasteride and minoxidil rather than a standalone solution. Some argue it could be better than finasteride due to its protection against testosterone, but its long-term efficacy remains debated.