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    Glossary Immunosuppressants

    medications that reduce the activity of the immune system

    Immunosuppressants, also known as immunosuppressive drugs, are medications that reduce the activity of the body's immune system. They are often used to prevent the rejection of transplanted organs and to treat autoimmune diseases, where the immune system mistakenly attacks the body's own tissues. By dampening the immune response, these drugs can help manage conditions like alopecia areata, where the immune system targets hair follicles, leading to hair loss.

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      community The DEFINITIVE cure for hairloss

       285 upvotes 1 year ago
      The conversation humorously suggests using immunosuppressants like ciclosporine and oral minoxidil for hair regrowth, with a satirical plan involving hair transplants from family members. It highlights the side effects and impracticality of such treatments, emphasizing the post's satirical nature.

      community Upcoming treatment ideas in the future

       11 upvotes 1 year ago
      Exploring future hair loss treatments, including immunosuppressants for hair transplants and hair cloning, with a focus on leveraging research from other medical fields. Current treatments like finasteride and minoxidil are effective for most, but there's a call for more funding and innovation in the hair loss industry.

      community OND-1 "Cyclosporine A” New hair loss treatment

      in Research/Science  28 upvotes 5 months ago
      Orient Bio is developing a PLGA formulated version of Cyclosporine A to stimulate hair growth without its immunosuppressant effects. Users discuss various treatments like Clascoterone, PP405, minoxidil, and tacrolimus, expressing hope for new developments and sharing personal experiences with these treatments.

      community Making your own RT1640 in China

      4 years ago
      RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

      community Forgotten 'Total Revival' Stack

      in Research/Science  42 upvotes 1 year ago
      Cyclosporine A is discussed as a powerful hair growth stimulant, potentially more effective than minoxidil, but concerns about safety and side effects, including cancer risk, limit its use. The conversation highlights the need for further research and experimentation with topical application, despite its risks.

      community What happened to the 40mg dutasteride daily and Cyclosporine dude?

      in Chat  40 upvotes 1 year ago
      A user previously claimed to take 40mg of dutasteride daily and planned to try Cyclosporine, but their account and comments have since been deleted, raising concerns about their well-being. Other users discussed the risks and effectiveness of high doses of dutasteride, with some sharing their own experiences using dutasteride, finasteride, and minoxidil for hair loss treatment.

      community Norwood reaper is really a jokester

       67 upvotes 2 months ago
      A user regrets having a hair transplant without using medications like finasteride or minoxidil, leading to further hair loss. They are now trying Koshine 1% after experiencing side effects from other treatments.

      community How do I look? - Hair transplant update.

       36 upvotes 8 months ago
      A user shared their hair transplant update, having received 4,300 grafts and choosing not to use medications like finasteride or minoxidil due to potential side effects and personal reasons. Many commenters expressed concern that without these medications, the user might experience further hair loss, suggesting that preventative treatments are important for maintaining transplant results.

      community can someone help me identify these pls

      in Treatment 10 months ago
      The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

      community Zix pre-made - zinc topical on scalp

       3 upvotes 1 year ago
      The user is experimenting with a zinc sulfate and B6 topical solution called "Zix" for hair loss, alongside using a zinc oxide scalp mask and low-level laser therapy (LLLT). They report minimal hair loss after three months of use and are seeking feedback from others who have tried similar treatments.

      community Fibrosing alopecia in a pattern distribution

      in Research/Science  14 upvotes 2 years ago
      A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

      community My Theory Of Androgenic Alopecia

       16 upvotes 9 months ago
      Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

      community Most Promising Future Hair Loss Treatments In 2026

       83 upvotes 1 week ago
      Promising hair loss treatments in 2026 include GT20029, a topical androgen receptor degrader, and VDPHL01, an extended-release oral minoxidil, both offering safer alternatives with fewer side effects. Other treatments like sublingual minoxidil, OND-1, JW0061, TDM-105795, and AMP-303 are also being explored.

      community Minokem-N cotains hydrocortisone?

       2 upvotes 1 year ago
      Minokem-N's composition is unclear, with concerns about unlisted hydrocortisone. Users discuss alternatives like AloATM, which lacks soothing agents, and the challenges of verifying ingredients.

      community How important are Retinoic and Hydrocortisone in topical serum?

       5 upvotes 1 year ago
      The conversation is about using a topical serum for hair loss with ingredients like finasteride and minoxidil, and the option to exclude retinoic acid and hydrocortisone due to concerns about long-term effects. One user prefers using only finasteride, avoiding minoxidil and retinoic acid, and plans to remove hydrocortisone in future orders.

      community Tretinoin to counter-act Minoxidil's skin effects?

       5 upvotes 6 years ago
      Minoxidil may cause dark circles and affect collagen, and Tretinoin might help counteract these effects. Users suggest caution with Tretinoin due to potential Vitamin A toxicity and recommend using it sparingly with sunscreen and moisturizer.

      community 1mg of finasteride/2 sessions of Kenalog injections/ Clobetasol (4 months into treatment)

       5 upvotes 2 months ago
      The user is undergoing treatment for hair loss using finasteride, Kenalog injections, and Clobetasol, along with vitamin D and collagen supplements. They are considering additional treatments like minoxidil and microneedling, and there is discussion about whether the hair loss is due to stress, alopecia areata, or a scarring condition like lichen planopilaris.

      community Anti inflammatories as an adjunct treatment

       1 upvotes 8 months ago
      Anti-inflammatories like curcumin, quercetin, and vitamin E may help with hair loss when used alongside treatments like finasteride and dutasteride. Ketoconazole is also noted for reducing scalp inflammation and improving scalp health.

      community Low Dose Naltrexone For Inflammatory Hair Loss

       10 upvotes 1 year ago
      Low Dose Naltrexone (LDN) may reduce inflammation in alopecia conditions. It is discussed as a potential adjunct treatment with finasteride or dutasteride for androgenic alopecia.

      community Hydrocortisone helps with itch

       4 upvotes 9 years ago
      Hydrocortisone helps relieve scalp itchiness, possibly caused by minoxidil. Users discuss its effectiveness for managing this side effect.

      community Xeljanz medication for alopecia universalis?

       4 upvotes 2 months ago
      A person with alopecia universalis is considering using Xeljanz but is advised that Olumiant is more effective for their condition. They are under a dermatologist's care and should expect gradual progress, as follicles dormant for 20 years are challenging to reactivate.

      community Ru-58841 vs KX-826/pyrilutamide while on steroids

       4 upvotes 1 year ago
      The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

      community New topical claims complete reversal of AGA in 3 months

       18 upvotes 9 years ago
      A new topical treatment called RT1640 claims to reverse AGA using cyclosporine A, Minoxidil, and a new chemical entity, RT175. Users are skeptical due to lack of clinical trial data and inconsistent before-and-after photos.

      community Running Gear- Preemptive Treatment

      in Product 11 months ago
      A 51-year-old on TRT plans to use steroids and is concerned about hair loss, considering topical treatments like Hair Rescue with RU58841 and finasteride, along with Nioxin shampoo. They are cautious about using oral DHT blockers due to potential interactions with steroids like Tren and Anavar.

      community Microneedling protocol and supplements

      3 years ago
      Microneedling for hair loss should avoid anti-inflammatory supplements like garlic, Vitamin E, fish oil, turmeric, and NSAIDs for 3 days before and 5 days after the procedure to enhance collagen production. Completely abstaining from these supplements may be unnecessary, but caution is advised around the procedure time.