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    Did you mean Gamma-Aminobutyric Acid?
    GlossaryGamma-Aminobutyric Acid

    neurotransmitter that inhibits nerve activity, promoting relaxation

    Gamma-Aminobutyric Acid, commonly known as GABA, is a neurotransmitter in the brain that inhibits nerve transmission, helping to regulate nervous system activity and reduce neuronal excitability. It plays a crucial role in promoting relaxation and reducing stress, and imbalances in GABA levels are associated with conditions like anxiety, epilepsy, and insomnia.

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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 3 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community Vitamin E

       20 upvotes 6 years ago
      Vitamin E was discussed as a treatment for hair shedding, with a specific form mentioned. A user shared a link to a study and started taking the Vitamin E variants used.

      community What happened to that guy who’s been drinking topical minoxidil?!

      in Chat  217 upvotes 1 month ago
      A user tried various hair growth treatments, including drinking topical minoxidil, using oral minoxidil and finasteride, and applying GHK-Cu, growth hormone peptides, and liposomal sulforaphane. They experienced thicker hair, while others discussed the risks and benefits of these methods.

      community Been doing daily 3% topical peppermint oil for 6+ months (never used minoxidil). Have had growth that seems as good as minoxidil. Might strenghten the idea that peppermint is a good low-cost treatment, that potentially works by another route than minoxidil.

      in Treatment  13 upvotes 2 years ago
      The user has been using finasteride, nizoral, microneedling, and recently added 3% peppermint oil to their hair loss treatment, experiencing regrowth similar to minoxidil. They suggest peppermint oil as a potentially effective, low-cost alternative or addition to minoxidil, with the added benefit of a pleasant smell and ease of use.

      community I just made my own PRP - DIY PRP

      in Research/Science  548 upvotes 1 year ago
      The post and conversation are about a user who made their own Platelet-Rich Plasma (PRP) for hair loss treatment at home, using their own blood and a centrifuge. The responses vary, with some users supporting the DIY approach to save money, others expressing concern about the safety and effectiveness of the method, and a few joking about the lengths people will go to combat hair loss.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 1 year ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community 35% regrowth brothers and sisters! More effective than Minox and Fin?

      in Treatment  107 upvotes 6 years ago
      A double-blind clinical study that found ingestion of tocotrienols resulted in a 34.5% increase in hair regrowth compared to the placebo group, and discussion about potential side effects and cost of supplementation with vitamin E pills. The conversation noted that it may be more effective than commonly used treatments like minoxidil and finasteride.

      community Fevipiprant 2019!

       17 upvotes 8 years ago
      The conversation discusses Fevipiprant, an asthma drug that may block CRTH2 and potentially stop male pattern baldness (MPB) without inhibiting DHT. It also mentions the use of finasteride and dutasteride for hair loss.