Some users experience side effects from finasteride and switch to alternatives like pyralutamide and a finasteride-minoxidil mix. These alternatives may reduce side effects while helping with hair loss.
A 21-year-old is using oral minoxidil, rosemary oil, saw palmetto, and pumpkin seed oil for hair regrowth but is advised to use finasteride or dutasteride for better results. The user is hesitant to use DHT blockers due to cost and is seeking advice on whether their current regimen is effective.
An arthritis drug, baricitinib, is discussed as a potential treatment for autoimmune alopecia, not androgenetic alopecia. Ritlecitinib is also mentioned as a possible treatment for scarring alopecia.
The conversation discusses using NAC and quercetin as supplements for hair loss, with some users also mentioning finasteride. NAC is highlighted for its potential benefits, but concerns about its safety and absorption are also raised.
A peptide-based delivery system for finasteride shows promise in reducing systemic side effects while maintaining hair growth effectiveness. Combining this with other treatments like minoxidil and RU58841 could enhance results with lower systemic absorption.
A user successfully regrew hair using 1mg finasteride, switching to 0.5mg dutasteride, and maintaining 5mg oral minoxidil, with significant improvements noted after switching to dutasteride. The user experienced shedding phases but ultimately achieved regrowth and is now comfortable without wearing a hat.
People discussed starting hair loss treatments like finasteride, dutasteride, and minoxidil due to personal experiences or comments about their hair loss. Some reported positive results, while others mentioned side effects or switching treatments.
Microneedling depth should be customized based on hair type and scalp area, with many users finding 0.5-0.6mm effective for miniaturized hairs to avoid damage. Users report varying pain levels and results, with some preferring shorter needle lengths and others using longer ones like 1.75mm for scalp health and density improvement.
Minoxidil alone is not effective for hair regrowth; adding a DHT blocker like finasteride or dutasteride is recommended. Dermastamping and micro-needling can enhance results, and some users suggest trying oral minoxidil or natural DHT blockers.
The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.
The "crunching" sound during microneedling is likely the needles penetrating the scalp's outer layers, not cutting hair. Users suggest using a derma stamp instead of a roller to avoid potential hair damage.
Topical finasteride may have higher systemic absorption and lower efficacy when using a Propylene Glycol/Ethanol formulation compared to the hydroxypropyl chitosan (HPCH) formulation. The safety profile of topical finasteride relies heavily on the HPCH formulation, and using standard solutions might lead to different pharmacokinetics.
The conversation discusses hair growth treatments, with the original poster avoiding minoxidil due to health concerns and considering serums with positive reviews. Alternatives like topical caffeine and redensyl are mentioned as options.
Skepticism about hair loss research motivations, suggesting financial interests hinder finding a cure. Mentions treatments like minoxidil, finasteride, and dutasteride, but notes they are not cures.
The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.
Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.
A user experienced hair thinning after using tamoxifen and bupropion and is now using topical dutasteride, alfatradiol, melatonin, adenosine, and specific shampoos for improvement. They are considering using steroids and are seeking advice on whether combining oral dutasteride with TRT/PEDs would affect hair health, with mixed opinions on the impact of testosterone and DHT on hair loss.
Microneedling alone is generally not effective for hair growth and is often combined with minoxidil for better results. Some users believe it helps with fibrosis and blood flow, but many see it as ineffective without additional treatments like minoxidil or finasteride.
The user experiences an itchy scalp despite using finasteride and ketoconazole shampoo for hair loss. Suggestions include trying different shampoos, switching to dutasteride, and using topical treatments for inflammation.
Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.
Microneedling before applying topical finasteride or dutasteride may enhance their effectiveness by increasing local absorption in the scalp, despite concerns about systemic absorption. Users discuss combining this method with oral treatments and minoxidil, noting potential benefits and side effects.
The conversation discusses hair transplants, including the use of techniques like FUE and the importance of a good donor area to avoid visible bald patches. It also touches on alternative treatments like Minoxidil, Finasteride, and Pyrolutimide, and debates the idea of embracing baldness versus seeking treatments.
Oral minoxidil and dutasteride are used for hair loss with mixed results. Some users report new growth, while others suggest scalp inflammation may be an issue.
User shared progress pictures after 3 months of using Minoxidil 5% and dermarolling, noting significant shedding but positive results. They plan to continue and may add finasteride.
NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.
Finasteride and dutasteride can show initial hair count increases within 12 weeks, but visible improvements often take longer, with many users reporting noticeable changes after a year or more. While early results may be seen under a microscope, significant cosmetic improvements typically require more time for hair to thicken and become visibly denser.
Minoxidil can be applied topically or taken orally, but caution is needed as it is dangerous for pets. Users discuss combining it with finasteride and other treatments, emphasizing the importance of proper application and monitoring for side effects.
Topical Dutasteride, especially in a liposomal base, is recommended for enhanced scalp DHT suppression when used with oral Dutasteride. It is suggested to apply it twice a week for effective results without significant systemic impact.
The conversation discusses using pumpkin seed oil and rosemary oil for hair thinning, with skepticism about their effectiveness compared to pharmaceutical options like finasteride and minoxidil. Some users suggest trying natural treatments, while others emphasize the proven success of pharmaceuticals.
PP405 is discussed as a potential hair loss treatment, but its effectiveness and safety are uncertain. Some users express skepticism, while others are hopeful, comparing it to existing treatments like Minoxidil and Finasteride.