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GlossaryEpidermal Stem Cells

specialized cells in the skin that regenerate and repair tissue

Epidermal Stem Cells, also known as Skin Stem Cells, are specialized cells found in the outermost layer of the skin, the epidermis. These cells have the unique ability to self-renew and differentiate into various cell types that make up the epidermis, playing a crucial role in skin regeneration, wound healing, and maintaining the skin's barrier function.

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community Clearing the air on how non-surgical treatments really work

18 upvotes 5 years ago

Treatments for hair loss, including finasteride, dutasteride, minoxidil, ketoconazole, microneedling, and low level laser light therapy, which aim to reduce DHT production, increase cell absorption and blood flow, and stimulate epidermal stem cells. It also stresses the importance of patience when using these treatments.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 667 upvotes 2 months ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

in Research/Science 198 upvotes 2 days ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community A Scientific Perspective in Microneedling for Alopecia

in Microneedling 43 upvotes 5 years ago

The post and conversation are about microneedling as a treatment for alopecia. It provides a comprehensive review of scientific literature on the technique and its application.

community Is it possible for androgenic alopecia to begin at early adolescent years?

in Chat 70 upvotes 1 year ago

Hair loss can begin in early adolescence and cause mental anguish. Treatments mentioned include eating cruciferous vegetables, engaging in physical activity, and maintaining scalp hygiene.

community Injecting stomach fat into the scalp could cure baldness in just six months

in Update 114 upvotes 6 years ago

A potential treatment for hair loss that involves injecting fat into the scalp; the role of testosterone and estrogen in thinning fat tissue under the skin; research on using lard to treat androgenic alopecia, as well as PRP + ACELL/amniotic stem cell treatments; and ongoing clinical trials by doctors involved in the study.

community Microneedling technique clarification

in Microneedling 16 upvotes 5 months ago

The conversation is about using a Dr. Pen for microneedling on a widow's peak, with advice to use a depth of 1.25mm and hold it in place for 10 seconds. The user is also using minoxidil.

community M32, almost 3 moths, fin oral 1,25g/daily + min 2xday + keto 2% shapoo 1/week microneedling once a week

in Progress Pictures 31 upvotes 1 year ago

A 32-year-old man has been treating his hair loss with daily oral finasteride (1.25g), twice-daily topical minoxidil, weekly ketoconazole 2% shampoo, and weekly microneedling for almost three months, with no side effects from finasteride. He started with a Hamilton Norwood scale rating of 5 and has seen improvement without experiencing pain by using a 0.8mm needle length for microneedling.

community Keratin microspheres - breakthrough

in Research/Science 13 upvotes 9 months ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

community How does it feel to microneedle at 0.3mm?

in Microneedling 17 upvotes 8 months ago

The conversation discusses microneedling for hair loss, with one user trying 0.3mm daily without feeling pain and questioning its effectiveness. Another user suggests that 0.3mm is too shallow and recommends 0.5mm twice a week or 0.75mm once a week for hair growth.

community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 109 upvotes 1 year ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 2 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community Alright boys, who’s willing to burn their scalp for science?

in Research/Science 765 upvotes 1 year ago

Researching the effects of scalp trauma on hair growth, with some users suggesting experimenting with a soldering iron or derma pen, and others bringing up studies that suggest this may be an effective treatment.

community My microneedling journey (no min, fin, etc)

in Microneedling 208 upvotes 2 months ago

The user experienced positive hair growth results using microneedling with rosemary and mint oil, without Minoxidil, Finasteride, or RU58841. They switched from a dermaroller to a microneedling pen and targeted different scalp areas weekly.

community I started rapidly diffuse thinning at 22. I'm 42 now and have as much hair as I did at 16. AMA

in Treatment 443 upvotes 4 years ago

Hair loss treatments like finasteride, minoxidil, ketoconazole, PRP, and microneedling helped maintain hair for 20 years. Research and try evidence-based treatments for best results.

community 6 months progress no fin 27m topical foam minox

in Progress Pictures 250 upvotes 1 year ago

The user has been using 5% Minoxidil foam twice daily, microneedling every two weeks, and Nizoral 2% shampoo weekly for hair loss treatment. They've seen improvements in their hairline and eyelashes, and are considering adding finasteride to their regimen.

community Damn, the trash hormone DHT was losing so hard it pulled the "old social media post" card

in Chat 196 upvotes 6 months ago

The conversation is about hair loss treatments, including minoxidil, finasteride, dutasteride, tretinoin, stemoxydine, adenosine, castor oil, baicalin, and bimatoprost. The user shares their nightly and morning routines and discusses the role of DHT in hair loss.

community Hair repigmentation of poliosis circumscripta in androgenetic alopecia patient treated with exosomes and fractional picosecond laser

in Product 2 upvotes 9 months ago

Exosomes combined with fractional picosecond laser treatment were effective in treating androgenetic alopecia and promoting repigmentation in white hair patches. The role of exosomes in hair repigmentation, particularly in conditions like poliosis, is not well-studied.

community Scalp slapping to increase blood flow?

in Treatment 22 upvotes 6 months ago

This post and conversation are about using scalp slapping to increase blood flow for hair growth. One user suggests using minoxidil instead.

community GT20029 Anageninc Market Availability

in Research/Science 164 upvotes 1 year ago

The conversation discusses the potential market release of a hair loss treatment called GT20029 by Anageninc, with users expressing interest and discussing the importance of safety and effectiveness. Some users plan to contact Anageninc to show demand for the product.

community Anyone using CB-03-01? What are you thoughts? How do you get it from powder to solution? What strength should be used?

in Treatment 6 upvotes 4 years ago

The conversation is about someone considering using CB-03-01 for hair loss but has ordered finasteride, which they are hesitant to use. They are seeking advice on how to prepare CB-03-01 from powder form and the appropriate strength to use.

community Topical Dutasteride. Does it work?

in Finasteride/Dutasteride 13 upvotes 6 months ago

Topical dutasteride may be effective for hair loss by staying in the scalp and minimizing bloodstream absorption, potentially improving hair results and reducing side effects. The user seeks advice on its effectiveness.

community Topical finasteride has affected my hormones

in Finasteride/Dutasteride 27 upvotes 11 months ago

A 21-year-old experienced hormone changes after using self-made topical finasteride for hair loss, including a 20% decrease in DHT, a 47% increase in testosterone, and a 39% increase in estradiol. The user previously used minoxidil and microneedling but is now seeking ways to balance hormones, possibly through supplements or dosage adjustments.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

in Finasteride/Dutasteride 72 upvotes 1 year ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

community Fin/min/microneedling ~9 months – no results, actually worse

in Progress Pictures 96 upvotes 1 year ago

User harlital shared their 9-month hair loss journey using finasteride, minoxidil, and microneedling but experienced worse results. Commenters suggested patience, checking for other causes, and considering dutasteride after 12-24 months if no improvement.

community How all hormones affect our hair follicles. Not just DHT. Take a look at this paper. Prolactin, melatonin, cortisol, progesterone, testosterone and more

in Research/Science 126 upvotes 2 years ago

The conversation discusses various factors affecting hair loss, not just DHT, and mentions treatments like Minoxidil, finasteride, and melatonin. Some users report personal experiences with these treatments and hormone tests, while others speculate on the role of hormones like prolactin and cortisol in hair loss.

community Sup Chooms?! How y’all living?!

in Progress Pictures 976 upvotes 7 months ago

A 35-year-old shared their 5-month hair regrowth progress, using 0.5mg oral finasteride daily, topical minoxidil/finasteride once daily, derma stamping 1-3 times a week, washing hair daily or every other day with peppermint soap, and using eczema lotion for scalp health. Commenters congratulated the individual on the significant improvement in their hairline.

community 3 months of progress USING HIMS FIN/MIN SPRAY + Dermarolling everyday (more so pressing the dermaroller then rolling)

in Progress Pictures 89 upvotes 1 year ago

The post is about a user's progress in treating hair loss using HIMS FIN/MIN spray and dermarolling. One user suggests taking the 1mg finasteride pill instead of using the topical spray, while another warns against microneedling every day.