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GlossaryEndocrine System

network of glands releasing hormones to regulate body functions

The endocrine system, also known as the hormonal system, is a network of glands and organs that produce, store, and release hormones directly into the bloodstream. These hormones regulate various bodily functions, including metabolism, growth, reproduction, and mood. Key components include the thyroid gland, adrenal glands, pituitary gland, and pancreas.

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community According to one study, topical spironolactone is more effective than topical finasteride for both men women.

in Treatment 12 upvotes 3 years ago

Topical spironolactone is more effective than topical finasteride for treating hair loss in both men and women. Oral spironolactone can affect testosterone, but the topical form doesn't impact the endocrine system.

community A philosophical discourse on the psychological effects of DHT versus hairloss. Hair or manliness: Choose one?

8 upvotes 5 years ago

The conversation discusses the role of DHT in male hair loss and the effectiveness of treatments like Finasteride, which reduces DHT, and RU58841, which blocks DHT from binding to scalp receptors. The user debates the trade-offs between maintaining hair and having a healthy endocrine system, suggesting RU58841 might allow for both.

community M21 I stopped finesterid 3 Months ago... this is how it looks now

in Finasteride/Dutasteride 176 upvotes 5 months ago

A user stopped finasteride due to side effects and rapid hair loss, considering a hair system. Others suggested alternatives like dutasteride, minoxidil, and topical finasteride.

community A Nuanced Look at Microdosing Topical Finasteride

in Finasteride/Dutasteride 85 upvotes 11 months ago

The conversation discusses using a low dose of topical finasteride to achieve hair benefits with minimal systemic exposure. Users share experiences and opinions on dosing, systemic buildup, and side effects of both topical and oral finasteride.

community Girl found my toppik

in Chat 221 upvotes 4 years ago

Girl finds guy's hair building fibers, sparking discussion on hair's role in attraction and self-esteem. Treatments like Minoxidil, finasteride, and hair systems are mentioned.

community This community was super helpful to me a while ago, but it feels so good to be off finasteride

in Shaved/buzzed 766 upvotes 1 year ago

The post is about a user who stopped using finasteride for hair loss and shaved his head, receiving positive feedback. The conversation includes discussions on side effects of finasteride, including potential fertility issues, and alternatives like minoxidil, dermarolling, and hair systems.

community I’ve been shaving my head for 15 years. Is there anything out there that can truly regrow hair?

in Hair Systems 1 year ago

A user who has been shaving his head for 15 years looking for potential treatments to regrow hair; the replies range from advice to try out medications such as finasteride and minoxidil, to suggestions of changing up his look with facial hair or hobbies.

community Reminder how little the average person knows about hair loss

in Satire 642 upvotes 1 year ago

How little the average person knows about hair loss and how it can be an unfairly stigmatized issue, even by people with little knowledge of it themselves. Some specific treatments that were discussed include finasteride, RU58841, dutasteride, minoxidil, pyritinol, dermarolling, and diet/lifestyle changes.

community here is why isotretinoin might cause hair loss and maybe why dupa happens.

in Research/Science 7 upvotes 1 year ago

Isotretinoin may cause hair loss by increasing DHT through a precursor androgen, DHEAS. Treatments like topical antiandrogens (RU58841, pyrilutamide) and drugs increasing PPAR-y expression (pioglitazone) might prevent this hair loss.

community Stress make you more androgen sensitive

in Chat 20 upvotes 5 months ago

Stress can increase androgen sensitivity, potentially worsening hair loss. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Questions about alfatradiol logistics

in Treatment 4 upvotes 1 year ago

The user is seeking help with using Ell-Cranell for hair loss treatment. They are unsure about the correct application method and dosage. They also inquire about combining microneedling with topical alfatradiol and question a study that referred to alfatradiol as a hair growth inhibitor in male mice.

community Pyrilutamide is working but not strong enough, how long should i wait for noticeable results?

in Update 3 upvotes 1 year ago

User discusses Pyrilutamide's effectiveness for hair loss, needing more time for results. Others suggest waiting 6-12 months and ask about side effects.

community 4+ Years on Dut: Update and AMA

in Update 113 upvotes 1 year ago

Hair loss treatments, such as Dutasteride, Minoxidil, and Finasteride. Advice is given to give the medications time to work and to consider a Hair Transplant in order to fill any gaps caused by continuing hair loss.

community I've been afraid to start Finasteride treatment for 5 years, on it for 2 weeks, regret that hadn't started it earlier and here's my story

in Finasteride/Dutasteride 31 upvotes 3 years ago

A 28-year-old male, losing hair since his teens, started taking 0.31 mg finasteride daily for two weeks with no side effects and regrets not starting earlier. He tried various treatments like minoxidil, scalp massages, and vitamins but found finasteride most effective.

community 26M Baseline blood work done before Finasteride

in Finasteride/Dutasteride 6 upvotes 3 years ago

A person considering finasteride for hair loss checked their hormone levels before starting treatment. They are concerned about the potential increase in estradiol and its effects, as well as the impact on their sex hormone-binding globulin (SHBG) and free testosterone levels.

community [25, F] [RANT] Shedding since March 2020. This just isn’t fair.

in Female 42 upvotes 3 years ago

User "missbloombastic" has been experiencing hair loss since 2016 and tried min, fin, multivitamins, and spiro with mixed results. Another user shares their struggle with hair loss and its impact on self-esteem, while a third user suggests checking blood tests and confirming the cause of hair loss.

community My Topical Dutasteride results. 14 months later (0.1%)

in Progress Pictures 82 upvotes 3 years ago

User shared their 14-month progress using topical Dutasteride at 0.1% for hair loss, with significant improvement and no side effects. Others discussed concerns about fertility and questioned the authenticity of the results.

community Finasteride isn’t going to work on the first week, month ffs..

in Finasteride/Dutasteride 70 upvotes 4 years ago

The conversation emphasizes the need for patience when using finasteride for hair loss, as it can take up to 2 years to see maximum results, and results vary from person to person. Some users also discuss dosage adjustments and side effects, highlighting individual differences in response to the treatment.

community I'm regrowing my hair while being on the harshest steroids

10 upvotes 6 years ago

The user is regrowing hair while using steroids by following a regimen that includes Rogaine, RU58841, Dutasteride, Nizoral, PGE2, and occasionally castor oil. Despite using harsh steroids like Tren, Masteron, and Proviron, the user reports successful hair regrowth.

community Anyone get bloodwork done? What numbers should I be looking for?

6 upvotes 9 years ago

The user had lab work done to check for thyroid issues and other factors related to hair loss. They are seeking advice on which lab results are important for understanding hair loss and what the optimal levels should be.

community How is it that golden era bodybuilders kept their hair while blasting gear while in the modern era most are bald? I’m convinced there’s something in our food and water causing MPB to speed up

in Satire 723 upvotes 1 year ago

The conversation is about the difference in hair loss between bodybuilders in the "Golden Era" and modern bodybuilders. Some users speculate that factors such as the types and doses of steroids used, genetics, diet, microplastics, and overall health may contribute to hair loss. Hair loss prevention medication and transplants are mentioned as potential treatments.

community 5Months 0.5mg Fin + 2.5mg Oral Min | UPDATE #2

in Progress Pictures 911 upvotes 1 year ago

The user, Salty-Peace-577, shared their 5-month update on using 0.5mg oral finasteride and 2.5mg oral minoxidil for hair loss. They experienced significant hair growth, particularly in their eyebrows, and shared their regimen and tips for hair growth. Some users in the conversation also discussed the side effects they experienced with different dosages of the medications.

community (UPDATE) 9 month progress on Minoxidil 5%(switched to 10% last 3months) and Finasteride 1mg per day, everyday.

in Progress Pictures 138 upvotes 2 years ago

User shared 9-month progress using Minoxidil 5% (switched to 10% last 3 months) and Finasteride 1mg daily for hair growth. Experienced improvement in hair volume, but crown still not fully filled; considering transplant if no further progress.

community Just found out I am Vitamin D deficient

in Treatment 58 upvotes 3 years ago

A user found out they are vitamin D deficient and was prescribed high-dose vitamin D supplements, asking if others had similar experiences and if it improved their hair. Some shared improved mood and testosterone levels after treatment, while another combined vitamin D supplements with finasteride due to family history of baldness.

community why do some people have such a severe personal vendetta against finasterid?

in Question 17 upvotes 6 years ago

A user is concerned about starting finasteride due to negative reports and potential side effects. Other users suggest talking to a doctor, considering personal tolerance, and note that side effects are rare.

community Well… I Did It. Estrogen Saved My Hairline

in Transgender 723 upvotes 2 months ago

OP transitioned and used Spironolactone, Estradiol Valerate, Minoxidil, and dermarolling, resulting in significant hair regrowth. They advise this method may not be suitable for cis men.

community 12 Months Hair Transplant Progress / 3500 Grafts (1 YEAR)

in Transplants 1116 upvotes 5 months ago

A user shared their 12-month progress after a 3500-graft hair transplant at Heva Clinic in Istanbul, choosing not to use minoxidil or finasteride. The results were praised, with comments noting the natural look and significant improvement.

community Just popped my first fin, excited as hell!

in Finasteride/Dutasteride 154 upvotes 5 months ago

A user shared their excitement about starting finasteride for hair loss after trying various ineffective methods. Other users discussed their experiences with finasteride, including shedding phases and side effects, with one mentioning using topical finasteride and minoxidil.

community Damn, the trash hormone DHT was losing so hard it pulled the "old social media post" card

in Chat 198 upvotes 5 months ago

The conversation is about hair loss treatments, including minoxidil, finasteride, dutasteride, tretinoin, stemoxydine, adenosine, castor oil, baicalin, and bimatoprost. The user shares their nightly and morning routines and discusses the role of DHT in hair loss.

community Post Finasteride Syndrome, A dangerous lie.

in Chat 142 upvotes 9 months ago

A user initially had side effects from finasteride, attributed them to anxiety and the nocebo effect, and after resuming the drug, experienced positive effects and now warns against misinformation about Post Finasteride Syndrome.