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GlossaryDisease Progression

worsening of a disease's symptoms and spread over time

Disease progression refers to the process by which a disease advances in severity over time. This can involve the worsening of symptoms, the spread of the disease to other parts of the body, or the development of complications. Understanding disease progression is crucial for both diagnosing the stage of a disease and planning appropriate treatment strategies. For example, in the context of alopecia, disease progression might involve the gradual increase in hair loss areas or the transition from patchy hair loss to more extensive baldness.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 1 month ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Let's be clear, does Finasteride stop MPB as long as it's taken?

in Finasteride/Dutasteride 170 upvotes 6 months ago

Finasteride is believed to slow down hair loss significantly, but may not completely stop it for everyone. Effectiveness and duration vary by individual, with some users experiencing positive results for over 10 years, while others see less benefit.

community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 6 months ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

community Will stopping ketoconazole make a difference?

in Ketoconazole 11 upvotes 6 months ago

The user has been using finasteride and ketoconazole for hair loss and is considering changing shampoos due to dryness caused by ketoconazole. Responses suggest that stopping ketoconazole won't affect hair loss unless the user has seborrheic dermatitis, and recommend using conditioner or using ketoconazole shampoo less frequently.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

in Research/Science 103 upvotes 2 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community Finasteride/dut. causes NAFLD,IR,diabetes,kidney dysfunction is it correct.

in Finasteride/Dutasteride 139 upvotes 1 year ago

Hair loss discussion mentions treatments like Finasteride, Dutasteride, and Minoxidil. Users share experiences, side effects, and advice on using these treatments.

community Finasteride, also known as Propecia or Proscar, treats male pattern baldness and enlarged prostate in millions of men worldwide. But a new study suggests the drug may also provide a surprising and life-saving benefit: lowering cholesterol and cutting the overall risk of cardiovascular disease.

in Research/Science 531 upvotes 7 months ago

The conversation discusses the potential benefits of finasteride (Fin) for lowering cholesterol and reducing cardiovascular disease risk, with users sharing personal experiences and opinions on the medication's effects on health and hair loss. Some users report positive changes in cholesterol levels after taking finasteride, while others are skeptical or joke about its effects.

community Dutasteride 1 year regression. Depressing. (With pictures for proof)

in Progress Pictures 14 upvotes 9 months ago

A user shared their experience of hair loss progression after one year on dutasteride, expressing disappointment with no improvement and considering other treatments like RU58841. Other users offered mixed responses, some seeing no change, others suggesting the hair loss might have been worse without treatment, and discussing the role of testosterone and DHT in hair loss.

community M21 I stopped finesterid 3 Months ago... this is how it looks now

in Finasteride/Dutasteride 176 upvotes 3 months ago

A user stopped finasteride due to side effects and rapid hair loss, considering a hair system. Others suggested alternatives like dutasteride, minoxidil, and topical finasteride.

community This guy loses all transplanted hair?!

in Transplants 160 upvotes 5 months ago

A man lost his transplanted hair despite using minoxidil because he wasn't on a DHT blocker like finasteride, which is essential to prevent further hair loss. The conversation emphasizes that hair transplants are not a cure and require maintenance with medications to preserve results.

community Personal experiment: tretinoin and diffuse thinning

in Treatment 9 upvotes 1 year ago

User experienced hair growth with finasteride and minoxidil, but after using tretinoin, faced aggressive thinning and hair loss. They plan to stop tretinoin for two months to see if the problem improves.

community Kintor Phase 2 Results released KX-826 (pyrilutamide)

in Research/Science 451 upvotes 2 years ago

Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

community The hardest hair protocol ever!

in Research/Science 11 upvotes 2 years ago

The user is using RU58841, finasteride, dutasteride, and minoxidil to slow down aggressive hair loss but is still experiencing hair shedding due to high testosterone levels. They plan to use ostarine to lower testosterone and prevent hair loss while maintaining muscle mass, and will continue using the other treatments.

community I believe CRISPR-on & CRISPR-off is an ultimate CURE for baldness, unlike Hair Cloning or hair loss treatments.

in Research/Science 22 upvotes 3 years ago

The conversation discusses CRISPR-on & CRISPR-off as a potential cure for baldness, contrasting it with hair cloning and other treatments like Minoxidil, finasteride, and RU58841. It also mentions the potential of mRNA for gene expression control and the prioritization of gene editing for severe genetic conditions.

community HairClone developing cell replacement treatments for Hair Loss

6 upvotes 5 years ago

HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.

community Found it. Sulforaphane, a phytochemical in broccoli sprouts, promotes hair growth (60% regeneration in mice) by accelerating the degradation of DHT.

110 upvotes 7 years ago

Sulforaphane, found in broccoli sprouts, promotes hair growth by degrading DHT. Users discuss its potential benefits and joke about unconventional application methods.

community Let's talk about natural options and last resorts.

in Chat 7 upvotes 5 months ago

The user discusses their long struggle with hair loss, considering various treatments like hair transplants, hair systems, and natural methods such as micro-needling, vitamin supplements, and a healthy lifestyle. They express concerns about side effects from drugs like finasteride and ultimately lean towards using a hair system for better appearance and confidence.

community Kintor’s GT20029 Phase 1 success

in Update 74 upvotes 1 year ago

Kintor's GT20029, a treatment for hair loss, has completed Phase 1 successfully, showing promise as an androgen receptor degrader that could potentially regrow hair. It is considered more effective than Pyrilutamide, with infrequent dosing and minimal systemic absorption.

community Physician here AMA – 30M oral Fin 1-1.25 mg daily

in Update 47 upvotes 2 years ago

Hair loss treatments, specifically the use of finasteride, microneedling and potentially oral minoxidil. People discussed their experiences with finasteride, its effects on sexual behaviors, as well as potential solutions such as tadalafil or using other growth factor signal peptides for hope in curing male pattern baldness.

community What other factors than DHT causes hair loss – and what to do about it?

in Treatment 2 years ago

Factors that can cause hair loss other than DHT, such as inflammation and diet, and potential treatments like scalp massages, minoxidil, citrulline, stretches, meditation, iron sulfate/Vitamin C, Vitamin D, protein and Dutasteride.

community Why I really believe the tension theory is the cause of MPB

in Research/Science 70 upvotes 3 years ago

The conversation discusses the tension theory as a cause of male pattern baldness (MPB), suggesting that scalp tension and reduced subcutaneous fat layer contribute to hair loss. Treatments mentioned include Minoxidil, finasteride, microneedling, scalp massages, and Botox.

community 2020 & now today. I'm disappointed to my results

in Progress Pictures 303 upvotes 4 days ago

The user is disappointed with their hair loss treatment results using Minoxidil, dermastamping, and ketoconazole shampoo. They are advised to add Finasteride or Dutasteride to block DHT for better results.

community a Year on Min,dut,keto,dermarolling, vitamins,diet/health

in Finasteride/Dutasteride 3897 upvotes 2 weeks ago

The user experienced significant hair regrowth using minoxidil, dutasteride, ketoconazole shampoo, dermarolling, vitamins, and a healthy diet. They reported no side effects and emphasized the importance of consistency.

community FINASTRIDE and switch to DUTASTRIDE, my experience

in Progress Pictures 133 upvotes 4 weeks ago

The user shared their experience with Finasteride and Dutasteride for hair loss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.

community I know that wanting a cure is unrealistic and too much to ask. But I at least want medicine that will work reliably for almost everyone.

in Chat 51 upvotes 1 month ago

The conversation is about the effectiveness of hair loss treatments like finasteride, dutasteride, and minoxidil. Users agree these treatments help maintain hair but don't guarantee miraculous regrowth, emphasizing early intervention for best results.

community Why do I have the feeling that this subreddit is flooded by Kintor employees?

in Chat 133 upvotes 1 month ago

Users discuss aggressive promotion of Koshine 826, suspecting Kintor employees are behind it. Concerns are raised about its effectiveness, with some preferring alternatives like finasteride and minoxidil.

community I think we all hop on estrogen. It's the only angle

in Satire 83 upvotes 1 month ago

The conversation humorously discusses hair loss treatments, including Minoxidil, finasteride, RU58841, and topical 17 alpha estradiol, with some users joking about transitioning to female to avoid baldness. The overall tone is satirical, emphasizing self-acceptance and the lengths people might consider for hair restoration.

community The worst thing about hair loss? Rant here!

in Chat 125 upvotes 3 months ago

Hair loss deeply affects self-esteem and mental health. Treatments mentioned include hair transplants, Minoxidil, Finasteride, and RU58841.

community We are manipulating our hormones, surely it's prudent to track bloodwork ?

in Finasteride/Dutasteride 64 upvotes 5 months ago

The conversation discusses whether individuals using hair loss treatments like Dutasteride (Dut) or Finasteride (Fin) should regularly check their hormone levels through bloodwork. Some argue it's important to monitor the effects of these medications on hormone levels, while others believe it's unnecessary if there are no side effects, citing cost and practicality concerns.

community Four years on finasteride (1 mg daily) and minoxidil (two years topical, two years oral) from age 24 (top) to 28 (bottom). Looks like I lost a bit of ground

in Progress Pictures 435 upvotes 6 months ago

The user shared progress pictures after using finasteride and minoxidil for hair loss over four years. Responses vary, with some seeing stabilization or slight improvement, and others noticing a small amount of hair loss.