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    GlossaryFranz diffusion cells

    laboratory devices measuring substance diffusion through barriers

    Franz diffusion cells are laboratory devices used to study the rate at which substances, such as drugs or cosmetic ingredients, pass through a barrier, typically skin or a synthetic membrane. They consist of two chambers separated by the barrier: one chamber holds the test substance, while the other contains a fluid that collects the diffused substance, allowing researchers to measure how quickly and effectively the substance penetrates the barrier.

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      community Sharing my 3.5 year journey, keep grinding guys

      in Progress Pictures  228 upvotes 8 months ago
      The user shared a 3.5-year hair loss treatment journey using 1 mg finasteride daily and minoxidil foam, noting significant improvement, especially in the third year. They also mentioned using Nizoral shampoo twice a week and supplements like vitamin D3, biotin, and omega 3 and 6.

      community Topical Dutasteride. Does it work?

      in Finasteride/Dutasteride  13 upvotes 7 months ago
      Topical dutasteride may be effective for hair loss by staying in the scalp and minimizing bloodstream absorption, potentially improving hair results and reducing side effects. The user seeks advice on its effectiveness.

      community Diffuse thinning is the worst man

      in Chat  248 upvotes 1 year ago
      The conversation is about the struggles of dealing with diffuse thinning at a young age and the lack of significant improvement after using treatments like finasteride and minoxidil. Some suggest additional methods like derma rolling, microneedling, and hair fibers, while others share their own experiences and encourage persistence with treatment.

      community He used Dutasteride for 20 years. Interview

      in Treatment  108 upvotes 2 months ago
      Dutasteride has been used for 20 years with some hair thickness improvement but no dramatic regrowth. The user also experimented with minoxidil, tretinoin, and peptides like BPC 157 for potential benefits in hair density and quality.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 4 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community fin 0.5 mg everday 6 months update

      in Finasteride/Dutasteride  28 upvotes 1 year ago
      The post discusses the experiences of individuals with diffuse hair thinning using finasteride, with many reporting no improvement or worsening conditions after 6 months. Various suggestions include persisting with the treatment, checking for underlying conditions, adding minoxidil for volume, adjusting dosage, and considering other potential causes like autoimmune responses and inflammation.

      community 15yo with severe anxiety from Norwood 2.5 and thinning

      in Finasteride/Dutasteride  15 upvotes 2 weeks ago
      A 15-year-old experiencing hair loss and anxiety is using minoxidil and microneedling but is advised against starting finasteride or dutasteride due to age. The discussion emphasizes consulting a doctor, considering hormonal evaluations, and exploring non-medication coping strategies.

      community Wtf have we been doing for the last 30 years

      in Treatment  548 upvotes 1 month ago
      Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

      community God bless H&M's fitting room lighting

      in Chat  197 upvotes 3 years ago
      Diffuse thinners find shopping challenging due to harsh overhead lighting, but H&M's side lighting in fitting rooms is more flattering. Many users humorously suggest banning overhead lighting to improve the shopping experience.

      community Jordan Peterson got a sick hair transplant!

      in Transplants  1074 upvotes 11 months ago
      The conversation is about Jordan Peterson allegedly getting a hair transplant, with various users mocking his way of speaking and debating the ethics of him potentially hiding the procedure. Some users discuss the natural look of the transplant and the implications of getting one at an older age.

      community Diffuse thinning is the worst possible balding experience

      in Chat  76 upvotes 1 year ago
      The conversation discusses the struggle with diffuse hair thinning and the effectiveness of treatments like finasteride, minoxidil, and RU58841. Users share experiences of hair thickening and shedding stopping with these treatments, but results vary and some are skeptical.

      community Where to find Botox online

      in Treatment  6 upvotes 3 years ago
      The user is looking for a place to buy genuine Botox online for scalp use. They are seeking recommendations for reliable sources.

      community 18 Months Minoxidil 5% Before & After

      in Progress Pictures  517 upvotes 3 months ago
      The user used Minoxidil 5% for 18 months, seeing improved hair density but no change in the crown area. They are cautious about using Finasteride again due to past gynecomastia.

      community Minoxidil and microneedling results

      in Is this regrowth?  20 upvotes 7 months ago
      A user reported noticeable hair regrowth after using 5% topical minoxidil daily and microneedling weekly since mid-January. They previously used dutasteride for four years with minimal effect.

      community Why nobody uses 0.25% (2.5mg/ml)?

      in Treatment  66 upvotes 1 year ago
      The conversation is about the effectiveness of 0.25% topical finasteride compared to other concentrations and forms. Users discuss its potential for better scalp DHT reduction and fewer side effects, with some preferring topical over oral treatments.