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GlossaryHair Follicle Damage

injury to structures responsible for hair growth, causing hair loss

Hair Follicle Damage, also known as Follicular Damage, refers to the harm or injury sustained by the hair follicles, which are the small structures in the skin responsible for hair growth. This damage can result from various factors such as physical trauma, chemical exposure, infections, or autoimmune conditions like alopecia areata. When hair follicles are damaged, it can lead to hair thinning, hair loss, or even permanent baldness if the follicles are severely affected.

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community 4 months 5% foam min + finasteride - 20 years old

in Progress Pictures 57 upvotes 8 months ago

A 20-year-old user experienced significant hair regrowth after using 5% minoxidil foam and finasteride for four months, starting to see results after two months with no side effects. They also cut off damaged hair ends, wash their hair every other day, and advise managing stress to improve hair loss outcomes.

community High Estrogen causing hair loss?

in Treatment 15 upvotes 1 year ago

A 24-year-old male using topical finasteride for hair loss is experiencing thinning despite treatment and has high estrogen levels. He is seeking advice on whether high estrogen could be causing hair loss and how others with high estrogen levels have addressed it.

community My story: Trying to halt diffuse hair loss for past couple of years but got acute hair fall after quitting minoxidil and finasteride on my dermatologist recommendation

in Chat 9 upvotes 3 days ago

A 22-year-old man experienced significant hair loss after stopping minoxidil and finasteride, causing emotional distress. He resumed these treatments and is considering dutasteride and microneedling to manage his hair loss.

community Shampoo except ketoconazole that works

in Product 8 upvotes 7 months ago

The conversation is about seeking shampoos that help with hair loss or hair thickening without ketoconazole, suggesting alternatives like minoxidil, finasteride, or stemoxydine. One reply suggests that most hair loss shampoos don't work as claimed.

community Lion Mane Part 2: Microneedling with Topicals, beneficial compounds, maybe?

in Microneedling 1 upvotes 7 months ago

The conversation discusses microneedling techniques and the use of Minoxidil, copper peptides, EGF, FGF, ceramides, and hydration serums to enhance hair growth. It explores optimizing scalp conditions and the potential benefits of various compounds in conjunction with microneedling.

community 3 months min, 2 months fin + microneedling. Mole for reference

in Progress Pictures 297 upvotes 1 year ago

User reports 3 months of Minoxidil, 2 months of Finasteride, and microneedling for hair loss treatment. Others compliment progress and suggest haircut for improved appearance.

community 1 year on Fin 1 mg. Switching to .4 mg Dut and oral 1.25 mg min

in Progress Pictures 448 upvotes 1 year ago

User shared 1-year progress on Fin 1 mg, switching to 0.4 mg Dut and oral 1.25 mg Min. Good results with Fin, biotin supplement, and biotin shampoo; trying Dut and oral Min for potential better results.

community Norwood 3.5 to Norwoord 5 wuth diffused thinning: damaged follicles all over the scalp due to 2 years of hair system usage. Has anyone faced a similar nightmare and recovered or revived their follicles? Desperately need help guys!

in Hair Systems 6 upvotes 1 year ago

User experienced hair loss from Norwood 3.5 to Norwood 5 with diffuse thinning after using a hair system for 2 years. Tried Redensyl, Capixyl, Bicapil, Biotin, multivitamins, Fin, and Min without significant improvement, seeking advice for hair recovery.

community Hair came back in 3 months at 39y/o.

in Progress Pictures 421 upvotes 1 year ago

A user shared their successful hair regrowth using a combination of minoxidil, caffeine, biotin, and RU58841, along with weekly dermarolling. However, others advised against the user's plan to switch to rosemary oil and microneedling only, emphasizing the importance of continuing the current treatment to maintain the results.

community NW3 > NW1: DUT and microneedling only

in Progress Pictures 789 upvotes 3 years ago

User Topher1999 achieved hair regrowth using Dutasteride 3 times a week and microneedling with Dr. Pen Ultima A6 every 2 weeks for 9 months. They believe microneedling is the main reason for hairline gains.

community Is ketoconazole shampoo bullshit?

in Ketoconazole 45 upvotes 1 year ago

The conversation is about the effectiveness of ketoconazole shampoo for hair loss. The conclusion is that ketoconazole shampoo can help with dandruff and seborrheic dermatitis, but it is not a strong enough treatment to stop or regrow hair. It is recommended to use it as an adjunct treatment along with finasteride or dutasteride.

community Alright boys, who’s willing to burn their scalp for science?

in Research/Science 765 upvotes 1 year ago

Researching the effects of scalp trauma on hair growth, with some users suggesting experimenting with a soldering iron or derma pen, and others bringing up studies that suggest this may be an effective treatment.

community Holy shit. Verteporfin may actually be the cure

in Research/Science 1016 upvotes 1 year ago

The post and conversation discuss Verteporfin's potential as a hair loss treatment. It's shown promise in regrowing hair after transplants and might be effective with microneedling.

community Will hair regenerate if androgen receptors are nuked?

in Research/Science 8 upvotes 1 year ago

Treatments for hair loss, such as using AR receptor blockers and degraders, to see if follicles can regenerate in the long term. The conversation also discusses how hair transplants could be a potential solution.

community Whats this thing on my scalp I tried killing it for over a year with salicylic acid and freeze off but it doesn’t help. Could this thing affect my follicles ? My hairloss started when this thing grew and minoxidil and fin haven’t been doing anything any other treatments?

in Minoxidil 32 upvotes 2 years ago

A user's scalp issue that may be causing their hair loss and potential treatments, such as salicylic acid, finasteride, minoxidil, ketoconazole shampoo, and visiting a dermatologist.

community The Big Fat Layer II

in Research/Science 26 upvotes 3 years ago

Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.

community Is There Any Chance Of Cancer In Follicle Neogenesis through Microneedling?

in Microneedling 15 upvotes 4 years ago

The conversation discusses concerns about the potential risk of cancer from creating new hair follicles through microneedling, due to stem cell division. Specific treatments mentioned include microneedling, caffeine-containing anti-hair loss shampoos, and other unspecified topicals.

community Can someone explain the science behind why Finasteride doesn't stop you from losing regrown hairs from minoxidil?

in Minoxidil 100 upvotes 3 weeks ago

Finasteride prevents further hair loss by blocking DHT, while minoxidil stimulates hair growth by prolonging the active phase of hair follicles. Stopping minoxidil can lead to loss of regrown hair because finasteride does not address the same growth mechanism.

community My Experience and a Discourse on "DUPA"

in Treatment 9 upvotes 6 months ago

The user discusses their hair loss experience, exploring various hypotheses including thyroid levels, vitamin D, DHEA, nutritional deficiency, diabetes, seborrheic dermatitis, lack of nutrition to hair follicles, chronic inflammation, female pattern hair loss causes, cortisol, and prolactin levels. They are currently using finasteride, beta-sitosterol, and have tried topical dutasteride and microneedling therapy.

community How is it possible for someone to be a non responder to ORAL minoxidil?

in Minoxidil 66 upvotes 8 months ago

Some individuals do not respond to oral minoxidil for hair loss, despite it generally working by improving blood flow to hair follicles. Factors like metabolism, drug interactions, and individual variations in the drug's activation may influence its effectiveness.

community Is hair thinning or loss associated with pain?

in Research/Science 6 upvotes 1 year ago

Hair thinning/loss associated with burning scalp pain. Finasteride helped relieve "DHT itch" for one person.

community Solving Hair Loss with Research at MIT

in Research/Science 594 upvotes 2 months ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

community Anybody else have family in denial over your hair loss?

in Chat 71 upvotes 5 months ago

A 20-year-old discusses family denial about his hair loss, diagnosed with seborrheic dermatitis, folliculitis, and male pattern baldness. He is prescribed Dutasteride and oral Minoxidil for treatment.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 74 upvotes 5 months ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community Testosterone and hair loss seeming irrelevance

in Research/Science 81 upvotes 1 year ago

The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

community Dude had better hair at over 100 years of age than many of us at 20

in Satire 1454 upvotes 1 year ago

Hair loss discussion mentions Native Americans' resistance to male pattern baldness and lack of facial hair. Users discuss genetics, sun exposure, and potential treatments like minoxidil and finasteride.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

in Research/Science 101 upvotes 2 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community 41 years old with 10+ years of hair loss. 2 months progress on Topical Fin&Min, Dermaroller, DHT blocker shampoo, Laser Cap and B12, Biotin, D3 Vitamins

in Progress Pictures 105 upvotes 3 years ago

A 41-year-old with over 10 years of hair loss showed progress after 2 months using topical finasteride and minoxidil, dermaroller, DHT blocker shampoo, laser cap, and vitamins B12, Biotin, D3. Commenters are impressed with the results and suggest continued treatment and focus on health for further improvement.

community CB-03-01 supposed hair loss cure

in Treatment 8 upvotes 3 years ago

The conversation discusses why CB-03-01, a potential hair loss treatment, isn't widely discussed despite evidence of its effectiveness and safety. Some users mention other treatments like melatonin, procianidin b2, and RU58841, debating their effectiveness and safety.

community Extreme hair and beard growth from Stemoxydine. Big 3 + 1?

in Product 23 upvotes 4 years ago

Using a combination of Stemoxydine, minoxidil, dutasteride, and keto shampoo to achieve extreme hair and beard growth. The user has experienced positive results with terminal hairs at the hairline and an increase in density to their stubble after several weeks of use.