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    Did you mean Cyclin D1?
    Glossary Cyclin D1

    regulates cell cycle progression from G1 to S phase

    Cyclin D1, also known as CCND1, is a protein that plays a crucial role in regulating the cell cycle, specifically the transition from the G1 phase to the S phase, where DNA replication occurs. It acts as a regulatory subunit for certain enzymes called cyclin-dependent kinases (CDKs), and its overexpression is often associated with various types of cancer, as it can lead to uncontrolled cell proliferation.

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      community Seasonal Hairloss

       5 upvotes 7 years ago
      The user experiences increased hair loss in winter, possibly due to lack of sun and vitamin D, and is using finasteride and vitamin D3 supplements to address it. Suggestions include using a red light lamp and maintaining vitamin D intake.

      community Thoughts on this hair product mix?

       22 upvotes 2 months ago
      The user is using a combination of 6% minoxidil, 0.3% finasteride spray in the morning, and 5% RU58841 in the evening for hair loss, considering it an aggressive approach. They are concerned about absorption issues and prefer topical treatments to avoid systemic side effects, especially while using anabolic steroids.

      community My way to recovery and advice - Hope this helps (m20)

      in Product  6 upvotes 1 year ago
      A 20-year-old shared their experience of reversing hair loss without using minoxidil or finasteride, instead relying on supplements like biotin, collagen, fish oil, saw palmetto, and various vitamins. They emphasized the importance of a balanced supplement schedule and noted improvements in hair health without experiencing additional shedding.

      community 2+ Years of Finasteride treatment - Stopped hair-loss, got regrowth, but

       24 upvotes 1 year ago
      The user experienced successful hair regrowth with Finasteride and Minoxidil but developed erectile dysfunction and abdominal pain, possibly due to medication or lifestyle changes. They plan to consult a urologist and consider adjusting medication or trying supplements like zinc, DIM, or boron.

      community Finasteride is ****ing magical

      in Update  314 upvotes 1 year ago
      Finasteride has led to significant hair regrowth for some users, with noticeable improvements in two months, but side effects like erectile dysfunction have caused some to stop using it. Some users combine finasteride with minoxidil and other supplements, despite concerns about side effects.

      community 3 years worth of bloodwork on Finasteride

      in Finasteride/Dutasteride  49 upvotes 1 year ago
      The user experienced a significant drop in libido and erectile issues after increasing their finasteride dosage, combining oral and topical treatments. They plan to take a break and resume using a lower concentration of topical finasteride to manage side effects.

      community Haunting study is making me considering cycling fin/dut

      in Research/Science  158 upvotes 1 year ago
      Concerns about the long-term effects of dutasteride and finasteride on fertility, with discussions on cycling these medications to mitigate risks. The conversation highlights skepticism about study methodologies and the importance of weighing treatment risks against potential fertility issues.

      community How to correctly dose Saw Palmetto and Pumpkin Seed Oil

      in Research/Science  5 upvotes 2 years ago
      The user takes 1 mg finasteride three times a week, topical minoxidil daily, and Saw Palmetto both topically and orally on non-finasteride days. They recently added 1 g of pumpkin seed oil daily to improve hair thickness and are seeking advice on dosing and cycling Saw Palmetto.

      community Shedding vitamin levels reminder

       8 upvotes 3 months ago
      Addressing hair loss by checking vitamin D and iron levels is crucial before adding more treatments. Supplementing these deficiencies can significantly reduce shedding.

      community Hair Loss “Cure” for Inflammation: Topical Roflumilast

      in Research/Science  32 upvotes 8 months ago
      Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

      community New molecule PP405 vs exercise

       36 upvotes 1 year ago
      PP405 targets hair follicle stem cells differently than exercise-induced lactate, suggesting exercise alone may not replicate its benefits. Minoxidil and finasteride are recommended alongside exercise for hair regrowth, with additional suggestions like spicy food and infrared exposure.

      community Would RU58841 work on a test cycle?

      in Technology  1 upvotes 2 years ago
      OP experienced side effects from finasteride and is considering using RU58841 to prevent hair loss during a testosterone cycle. They have also used minoxidil, Nizoral, alfatradiol, and fluridil successfully.

      community Let Me Sell You on NAC

       17 upvotes 7 years ago
      The conversation discusses using NAC (N-Acetyl Cysteine) alongside minoxidil and finasteride for hair loss, with some users noting potential hairline improvement and increased energy. The original poster reduced their finasteride dosage due to mental decline and anxiety, and while NAC's effects on hair are anecdotal, it is considered low-risk with other health benefits.

      community Stopped on fin, diffuse thinner, white hairs meaning

      in Finasteride/Dutasteride  5 upvotes 3 weeks ago
      The user stopped using finasteride and noticed diffuse thinning and white hairs on the crown, considering restarting finasteride and adding minoxidil. White hairs are miniaturized follicles that may regain pigment and thickness with treatment, and it's suggested to wait 12 months before considering a hair transplant.

      community 0.5 Dutasteride 8 months shedding

      in Finasteride/Dutasteride  6 upvotes 2 months ago
      The conversation discusses ongoing hair shedding while using 0.5 mg Dutasteride for 8 months, with users suggesting patience as it can take up to 18 months to see results. Some users also mention considering or using oral Minoxidil alongside Dutasteride.

      community One for the long term OG’s fin

      in Update  8 upvotes 5 months ago
      The user has been using finasteride and minoxidil for nearly three years, maintaining and possibly regrowing hair despite noticing shedding and miniaturized hairs. They are considering adding another treatment due to concerns about ongoing hair loss.

      community M22 with 2 years of treatment min/fin/microneedle/ketoconazole

      in Is this regrowth?  10 upvotes 5 months ago
      A 22-year-old male has been using oral minoxidil, oral finasteride, microneedling, and ketoconazole for hair loss treatment over two years, experiencing some regrowth and maintenance. He reports side effects from finasteride, including erectile dysfunction, and slight libido impact from minoxidil.

      community Hair cloning breakthrough, this might just be the big one ?

       418 upvotes 6 months ago
      Japanese scientists discovered ABM cells, enabling successful human hair follicle cloning, potentially curing hair loss. The treatment may be available in Japan by 2028, but it will be expensive and require travel.

      community Feeling hopeless even on nuclear stack

       25 upvotes 7 months ago
      The user feels hopeless about hair loss despite using finasteride, dutasteride, minoxidil, and RU58841, and having a hair transplant. They are advised to maintain consistency in treatment, consider increasing dutasteride dosage, and explore topical solutions for better results.

      community if hair follicle miniaturization happens slowly and gradually over a few hair cycles then wouldn't that mean that to regain maximum or top thickness from treatment you would at least need 5-10 years?

      in Research/Science  53 upvotes 10 months ago
      Hair regrowth from treatments like finasteride, dutasteride, and minoxidil can take several years, with most visible results appearing within 1-2 years and potential improvements continuing up to 10 years. Consistency and patience are crucial for achieving maximum hair thickness, as hair miniaturization and regrowth are gradual processes.

      community Creatine and ru-58841 experiences?

       1 upvotes 1 year ago
      RU58841 is preferred over finasteride for blocking DHT on the scalp, especially for those with aggressive MPB. Creatine is associated with increased hair shedding, even when using RU58841.

      community Should I stop taking Ashwaganda while trying to regrow my hair?

       4 upvotes 2 years ago
      A 20-year-old with aggressive hair loss uses finasteride, dermastamping, ketoconazole shampoo, and a castor oil and rosemary oil mix. They are uncertain about continuing Ashwagandha due to mixed effects on hair loss and anxiety.