Does Topical Finasteride Directly Reducing Scalp DHT? Finasteride/Dutasteride 5/17/2023
Topical finasteride reduces scalp DHT, with some going systemic. Using 0.025% at 1ml per day can stabilize hair loss without side effects.
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6 / 6 resultscommunity Is Scalp DHT more important than Serum DHT?
The user lost ground on oral finasteride and plans to switch to topical finasteride/minoxidil and microneedling. They are curious if topical treatments are more effective than oral ones.
community What Do You Guys Think of This Article That Claims Low Dosage Topical Finastride Has No Effect on Serum DHT
Low-dose topical finasteride may reduce scalp DHT with fewer side effects than oral finasteride, though it can still lower blood serum DHT. Users report varying experiences, with some finding topical use effective and side-effect-free, while others note significant DHT suppression.
community Is it sufficient to block scalp DHT topically, or is it also necessary to reduce serum DHT? (My Question is Elaborated Below)
Topical finasteride can be as effective as oral finasteride for hair regrowth with fewer systemic side effects, but precise dosing is essential. Combining oral dutasteride with topical finasteride is not recommended due to dutasteride's stronger inhibition.
community Why a lot of people seems to hate on topical fin even though it suppresses more scalp dht?
Topical finasteride may reduce more scalp DHT but is seen as inconsistent and messy compared to oral finasteride. Users report mixed results with both forms, with some preferring oral for its convenience and consistent dosing, while others find topical effective but harder to apply.
community My case study: DHT serum levels unresponsive to higher topical fin dosages.
The user has been using liposomal topical finasteride since late 2022, progressively increasing the dose, but DHT serum levels remain largely unchanged. Despite using finasteride, minoxidil, microneedling, and ketoconazole, hair condition has neither improved nor worsened.
community Attacking DHT synergistically both locally at the scalp and systemically = Greater Success??
The user has been using oral Dutasteride, RU58841, and Minoxidil for three years without success and is considering adding topical Finasteride or Dutasteride to target DHT both locally and systemically. Other users suggest sticking to a consistent treatment plan, exploring different combinations, and considering other factors like potential misdiagnosis or inconsistent medication use.
Related Research
6 / 6 resultsresearch Faculty Opinions recommendation of Topical finasteride for the treatment of male androgenetic alopecia and female pattern hair loss: a review of the current literature.
Topical finasteride is promising for hair loss with minimal side effects but needs more research and approval.
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In this study, researchers found that topical treatment with adenosine improved hair growth and thickness by significantly increasing hair density and thickness after four months in vivo, with results comparable to minoxidil, potentially due to adenosine's anti-androgenic effects.
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This study found that Lepidium sativum seed extract showed potential in treating alopecia in rats by reducing 5(alpha)-dihydrotestosterone levels and improving hair length compared to minoxidil.
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