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GlossaryCyclin D1

regulates cell cycle progression from G1 to S phase

Cyclin D1, also known as CCND1, is a protein that plays a crucial role in regulating the cell cycle, specifically the transition from the G1 phase to the S phase, where DNA replication occurs. It acts as a regulatory subunit for certain enzymes called cyclin-dependent kinases (CDKs), and its overexpression is often associated with various types of cancer, as it can lead to uncontrolled cell proliferation.

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community Table of the relationship between physical exercise and the regeneration of the deminiaturized hair follicle

in Research/Science 44 upvotes 1 month ago

Exercise, especially leg workouts, combined with finasteride and minoxidil, may enhance hair regrowth. Cold exposure, like cold showers, might further boost results.

community Lifestyle choices and your hair....

6 upvotes 5 years ago

A person noticed increased hair thinning after changing their workout routine from cycling to weightlifting, which also coincided with a rise in testosterone levels. They are considering stopping intense workouts, switching to yoga, cutting out caffeine, and re-evaluating after a few months to see if it improves their hair condition.

community Diffuse thinning hair texture changes

in Chat 1 upvotes 4 months ago

A user experiencing diffuse thinning since age 18 describes their hair as unhealthy, dry, thin, and hard, with texture changes cycling between good and bad every few weeks. They are not on any medication, only taking vitamins and supplements.

community Progress, 2nd shed and Drug resistance

in Progress Pictures 28 upvotes 8 months ago

User shares 8-month progress on oral finasteride and minoxidil, noting initial success followed by a second shed. They seek advice on drug resistance and pill efficacy, with responses suggesting to push through the shed and consider the impact of cycling off minoxidil.

community How to correctly dose Saw Palmetto and Pumpkin Seed Oil

in Research/Science 5 upvotes 6 months ago

The user takes 1 mg finasteride three times a week, topical minoxidil daily, and Saw Palmetto both topically and orally on non-finasteride days. They recently added 1 g of pumpkin seed oil daily to improve hair thickness and are seeking advice on dosing and cycling Saw Palmetto.

community How long does an RU58841 bottle last you?

in Product 8 upvotes 1 year ago

User asks how long RU58841 bottle lasts, inquires about application, quantities, and mixing at home.

community Would RU58841 work on a test cycle?

in Technology 1 upvotes 1 month ago

OP experienced side effects from finasteride and is considering using RU58841 to prevent hair loss during a testosterone cycle. They have also used minoxidil, Nizoral, alfatradiol, and fluridil successfully.

community Topical Dutasteride And Sperm Quality ?

in Finasteride/Dutasteride 1 upvotes 5 months ago

A user is concerned about the impact of topical dutasteride on sperm quality and potential long-term fertility issues. They are using microneedling with a 0.025% dutasteride solution and are seeking information on whether sperm parameters return to normal after stopping the drug.

community Does Topical Finasteride Directly Reducing Scalp DHT?

in Finasteride/Dutasteride 15 upvotes 1 year ago

Topical finasteride reduces scalp DHT, with some going systemic. Using 0.025% at 1ml per day can stabilize hair loss without side effects.

community Zero progress and hair slightly getting worse

in Chat 7 upvotes 2 months ago

A 21-year-old has been using 1 mg of finasteride and 1 mg of oral minoxidil for 10 months with no progress and worsening hair. They are considering switching to dutasteride and are seeking success stories and advice.

community Physio-metabolic method (antiandrogen, minoxidil, leg training and cold)

in Treatments 309 upvotes 4 months ago

The method combines finasteride, minoxidil, intense leg exercises, and cold exposure to treat androgenetic alopecia. It aims to boost metabolism and reduce androgenic effects, enhancing hair growth.

community 8 month progress so far (Sep 2023 - April 2024)

in Progress Pictures 371 upvotes 6 months ago

The user saw improvement in hair loss after 8 months by taking Finasteride three times a week, using Minoxidil, derma rolling once a week, and using Ketoconazole shampoo twice a week. They also mentioned working out and taking supplements.

community 6.5 Month Progression 33/Female

in Female 41 upvotes 1 year ago

Maintaining scalp hair and minimizing shedding, treatments used such as Procapil, supplements, topical caffeine, topical estrogen, and scalp massage; suggestions for anagen extenders or pharmaceuticals to help with a short anagen phase.

community Topical rapamycin, metformin, a-kg grow hair

in Research/Science 13 upvotes 4 years ago

The conversation discusses the potential of topical rapamycin, metformin, and alpha-ketoglutarate (a-KG) for hair growth, with skepticism expressed about their effectiveness based on personal experience and existing use. It also mentions AICAR, known as cardarine or GW, which is not suitable for long-term use due to cancer risks in animal studies and its similarity to metformin.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 2 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Fin and Oral Minoxidil completely changed my hair texture (8months progress)

in Progress Pictures 353 upvotes 2 months ago

Finasteride and oral minoxidil significantly improved hair texture and thickness over 8 months. The user also experienced increased hair growth on the beard and eyebrows.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

in Research/Science 486 upvotes 3 months ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community 5 months of 1mg Fin, weekly 1.5mm microneedling and daily 2mg copper peptide injections

in Progress Pictures 77 upvotes 4 months ago

The user shared progress pictures after 5 months of using 1mg finasteride, weekly 1.5mm microneedling, and daily 2mg copper peptide injections. They discussed their hair loss treatment and results.

community 51M - 1mg Oral Fin daily, 5% topical min twice daily, dermarolling 0.3mm daily/1mm weekly, Nizoral twice a week. Photos are 2 months apart

in Is this regrowth? 87 upvotes 5 months ago

A 51-year-old man uses 1mg oral finasteride daily, 5% topical minoxidil twice daily, dermarolling, and Nizoral twice a week for hair regrowth. He shows significant progress after two months and is happy with the improvement.

community Tropical growth stimulants other than minoxidil

in Treatment 11 upvotes 5 months ago

The conversation discusses alternative hair growth treatments to minoxidil, including Stemoxydine, Tretinoin, adenosine, Baicalin, castor oil, Latanoprost/bimatoprost, and Redensyl. Users share their experiences and opinions on the efficacy of these treatments.

community AGA responded to steroid shots? Biopsy wrong? Please help!

in Female 2 upvotes 5 months ago

A woman with AGA is using spironolactone, dutasteride, finasteride, oral minoxidil, bicalutamide, and anti-androgenic birth control but still experiences worsening hair loss. Steroid shots temporarily stop her hair shedding, leading her to question her biopsy results.

community How to get rid of Estradiol Problems

in Finasteride/Dutasteride 6 upvotes 7 months ago

The conversation discusses managing estradiol problems during finasteride treatment. Suggestions include stopping finasteride every 3 months for 2-3 weeks or reducing the dosage.

community (M28) 3 months progress on minoxidil 5%

in Progress Pictures 76 upvotes 7 months ago

A 28-year-old male showed hair regrowth after 3 months using 5% liquid minoxidil twice daily and weekly dermarolling with a 1mm roller. Someone suggested adding finasteride to the treatment.

community Can Fin and Min save my hair? (2 months old)

in Satire 2170 upvotes 7 months ago

The conversation jokes about using hair loss treatments like finasteride, minoxidil, and derma rolling on a baby, with suggestions ranging from starting treatment immediately to accepting baldness and focusing on other aspects of life. Some users suggest extreme measures like hair transplants in Turkey.

community 7 months of dutasteride progress after fin lost it's effectiveness.

in Progress Pictures 40 upvotes 8 months ago

After 6 years of finasteride losing effectiveness for hair loss, the user switched to dutasteride and topical minoxidil, seeing good progress after 7 months without significant side effects. They transitioned from finasteride to dutasteride over 2 months against doctor's advice.

community A Complete Guide to Hair Loss for Beginners

in Research/Science 531 upvotes 10 months ago

The conversation is a guide on treating hair loss, discussing finasteride and dutasteride to lower DHT, minoxidil for growth, ketoconazole shampoo for scalp health, and dermarolling for regeneration. RU58841 is mentioned as a DHT blocker but not recommended due to safety concerns.

community 2 and a half years progress and update

in Progress Pictures 318 upvotes 11 months ago

After 2.5 years of using 1mg finasteride daily, 5% minoxidil foam twice daily, and weekly micro-needling, the user reports thicker, healthier hair without further loss. They noticed initial regrowth at 3 months, with significant improvement up to 18 months, and no negative side effects from the treatment.

community 11 years on only fin, it can work! 19yo - 30yo

in Progress Pictures 212 upvotes 11 months ago

A user shared progress pictures showing improvement in hair thickness over 11 years using only finasteride, taken three times a week, with no side effects. Commenters reacted positively, with one wishing they had started treatment earlier.

community Nest topical compound stack to fight hair loss

in Treatment 1 upvotes 1 year ago

The user is seeking advice for the best topical treatment to combat their ongoing hair loss, despite already using oral dutasteride, RU-58841, and minoxidil. They are considering adding CB-03-01 or topical Spiro to their regimen to lower testosterone levels at the follicles.

community I'm gonna be bald by 20 and I'm not even exagerrating. Wtf do I even do?

in Chat 77 upvotes 1 year ago

A 16-year-old is experiencing early male pattern baldness and is considering using Minoxidil now and Finasteride after turning 18. Another user shared a positive experience with topical Minoxidil and Finasteride, noting improvement in hair thickness and no side effects.