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Did you mean Chronic Inflammatory Disease?

GlossaryChronic Inflammation

long-term immune response causing tissue damage and disease

Chronic inflammation, also known as persistent inflammation, is a prolonged and often harmful immune response that can last for months or even years. Unlike acute inflammation, which is a short-term response to injury or infection, chronic inflammation can result from ongoing exposure to irritants, autoimmune disorders, or unresolved acute inflammation. This persistent state can lead to tissue damage and is associated with various diseases, including arthritis, cardiovascular disease, and certain types of alopecia.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 2 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community I lost the fight against MPB at age 22 despite being on treatments.

in Finasteride/Dutasteride 72 upvotes 1 year ago

The user "ajsr8" shared their story of hair loss despite being on treatments. They started using finasteride in 2019 and later tried topical minoxidil, but it didn't seem to work. They also experienced side effects from other treatments. They are considering cutting off their hair and stopping the medications if there is no improvement in three months. Other users suggested trying different treatments and getting a blood test to check for underlying conditions.

community How I started reversing Male Pattern Baldness naturally ?

in Question 6 upvotes 7 years ago

The user reversed male pattern baldness using a pro-thyroid diet, lifestyle changes, and scalp stimulation exercises, without Minoxidil or Finasteride. They reported reduced dandruff, itchiness, oiliness, and experienced hair regrowth and thickening over 15 months.

community How uninformed the general public is about hair loss

in Chat 313 upvotes 9 months ago

The conversation highlights the general public's lack of knowledge about hair loss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.

community Hair much worse after 6 months?

in Progress Pictures 230 upvotes 1 year ago

A user experienced significant hair loss after 6 months of using 0.5mg finasteride daily. Suggestions from others included trying Dutasteride and Minoxidil, getting professional help from a dermatologist, and addressing high iron levels that could be contributing to the hair loss.

community 3 months progress with Finasteride 0.5mg/daily, Minoxidil foam5% 2x daily, Stemoxydine 2x daily, Microneedling(M8) 1.5mm 1x per week, Saw Palmetto 400mg/day, peppermint and jojoba oils daily, Ketoconazole 2% shampoo 3x/week, Purador shampoo/conditioner every day.

in Progress Pictures 337 upvotes 2 years ago

Jordan-Iliad has been using a combination of finasteride, minoxidil, stemoxydine, microneedling, saw palmetto, peppermint and jojoba oils, ketoconazole shampoo, and Purador shampoo/conditioner for 3 months to treat their hair loss with stunning results. They have also recently started taking oral minoxidil 1.25mg/day in hopes of achieving even better results over the next 3 months.

community Why I deleted my YouTube channel Part I

in Update 118 upvotes 3 years ago

A YouTuber named Kevin, also known as Rider_Of_Roach, who deleted his YouTube channel due to personal attacks and controversy surrounding his views on hair loss treatments. He advocated for FDA-approved treatments like finasteride and minoxidil but faced backlash from those who disagreed with him. The conversation also discusses his past trolling behavior and a lawsuit he filed against a website that published false information about him. Despite some disagreements, many viewers appreciated his research-based content and hope to see him return in the future.

community I’m 14 years old and I’m losing more hair than my dad. I’ve gone to the doctor 2 times because of this and I’ve received no help. I’m starting to feel like It’s worthless and my hairs gonna look like this forever. I don’t know how anyone could help me but it’s always worth a shot.

in Treatment 4 years ago

A 14 year old who is experiencing hair loss and has not received any help from the doctor, with advice being given to try different doctors, get tested for underlying conditions and intolerances, buzz it short as an option and treatments that could slow down or reverse the hair loss such as minoxidil, finasteride, RU58841 and addressing the cause of the hair loss.

community For hair loss - zinc is your friend

in Chat 43 upvotes 2 years ago

Zinc supplements can make existing hair thicker and fuller but do not cure or slow hair loss. Long-term zinc use requires copper supplementation to avoid deficiencies.

community Dutasteride takes 1-3 months to work in the scalp. Not weeks. Be careful.

in Finasteride/Dutasteride 41 upvotes 3 months ago

Dutasteride takes 1-3 months to affect scalp DHT levels, not just a week. The prostate absorbs Dutasteride faster than the scalp due to different vascular networks and enzyme densities.

community How much dht does Nizoral shampoo block?

in Ketoconazole 101 upvotes 3 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, RU58841, and Nizoral shampoo. Nizoral's effectiveness is debated, with some suggesting it works as a weak antagonist for androgen receptors, while others attribute its benefits to anti-fungal and anti-inflammatory properties.

community Sunlight: Does it Stimulate Hair Growth or Hair Loss?

in Research/Science 61 upvotes 7 months ago

The conversation discusses whether sunlight exposure affects hair growth or loss, with mixed anecdotes and theories but no clear consensus. Some suggest moderate sunlight can benefit hair by providing vitamin D, while others doubt its effectiveness compared to treatments like Minoxidil or finasteride.

community Scalp Inflammation is eating my hair!

in Chat 26 upvotes 7 months ago

A user with seborrheic dermatitis is experiencing bald spots and hair thinning despite changing their diet and taking oral minoxidil. Another user suggests using ketoconazole shampoo properly, using a scalp massager, applying rosemary/peppermint oil, keeping hair short, and taking fish oil to improve scalp health.

community Opinions on Scalp fibrosis and DHT?

in Research/Science 9 upvotes 2 years ago

The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

community Reducing tension on the back, sides and top of head causes hair growth in MPB sufferers. Studies inside

15 upvotes 7 years ago

Reducing scalp tension can help reverse male pattern baldness (MPB). Firm scalp massages and scalp stretching exercises are beneficial.

community My hair loss theory and what I did to stop my hair loss. 6 years of stabilization.

in Treatment 7 upvotes 4 years ago

A user shared their personal theory on hair loss, suggesting it's caused by reduced blood flow and scalp calcification rather than DHT, and claimed to have stopped their hair loss by massaging the scalp, using acid peels, and applying oils and copper peptides. They have not noticed further hair loss for six years since starting this routine.

community Interesting article links major MPB theories to western diet (and life-style)

in Research/Science 56 upvotes 3 days ago

community After Years of Treatment, I'm Shaving my Head and Giving Up

in Shaved/buzzed 119 upvotes 1 week ago

After years of using dutasteride and oral minoxidil without success, the individual decided to shave their head and stop treatment. They considered scalp micropigmentation and hair systems but ultimately accepted their hair loss.

community Creatine made all my high DHT symptoms return

in Research/Science 78 upvotes 2 weeks ago

Creatine may increase DHT levels, potentially causing symptoms like acne, oily hair, and hair shedding. Users report mixed experiences, with some avoiding creatine due to hair loss concerns and others seeing no impact.

community How essential is scalp biopsy when dealing with hair loss?

in Treatment 6 upvotes 1 month ago

The user experienced hair loss despite using Fin and Min for 12 years and switched to Dutasteride, RU58841, and Keto scalp serum, but shedding and itch persist. They are considering increasing Dutasteride to 2.5mg and questioning the necessity of a scalp biopsy, with mixed opinions on its usefulness.

community FINASTRIDE and switch to DUTASTRIDE, my experience

in Progress Pictures 135 upvotes 2 months ago

The user shared their experience with Finasteride and Dutasteride for hair loss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.

community A Different Take on Curing MBP

16 upvotes 5 years ago

Addressing hair loss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.

community I am actually regrowing my hairline without minoxidil or finasteride (mechanical stimulation)

128 upvotes 6 years ago

Regrowing hairline without the use of Minoxidil or Finasteride, and instead using mechanical stimulation such as Derma Roller, Nizoral, Zinc Pyrithione, Scalp Massage, Scalp Exercise, Fish Oil and other topical solutions. It is cautioned that there are risks associated with not using medically-prescribed treatments, but it is suggested to consider mechanical stimulation in addition to those prescribed treatments.

community Doctor says i shouldn't take fin because its "hormonal"

in Finasteride/Dutasteride 104 upvotes 3 months ago

A user in Turkey was advised by a dermatologist to avoid finasteride due to its hormonal effects and was prescribed minoxidil, shampoo, and vitamins instead. The user is considering seeking another doctor's opinion or buying finasteride directly from a pharmacy.

community How is it possible for someone to be a non responder to ORAL minoxidil?

in Minoxidil 66 upvotes 7 months ago

Some individuals do not respond to oral minoxidil for hair loss, despite it generally working by improving blood flow to hair follicles. Factors like metabolism, drug interactions, and individual variations in the drug's activation may influence its effectiveness.

community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 7 months ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

community I’ve read multiple times that Fin increases hair quality… NOT for me!

in Treatment 97 upvotes 1 year ago

A user has been on finasteride for 6 months and feels their hair quality has worsened, experiencing more hair loss and scalp irritation. They are considering seeing a dermatologist, while others suggest the issue might be unrelated to finasteride, possibly due to deficiencies or other conditions.

community 9 months fin 0.33mg daily - everything’s coming up millhouse

in Progress Pictures 81 upvotes 1 year ago

User started oral finasteride 0.33mg daily and later made a topical solution with cetirizine and stemoxydine. They experienced hair growth progress after 8-9 months and discussed factors affecting their results.

community Regrowing my hair/line without Min or Fin September (update) mechanical stimulation

in Finasteride 24 upvotes 6 years ago

The user regrew their hairline using mechanical stimulation, including a 1.5mm derma roller weekly, daily scalp massages, and other treatments like Nizoral, zinc pyrithione, fish oil, and Lipogaine The Big 5. They did not use Minoxidil or finasteride.