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GlossaryCardiovascular Diseases

disorders affecting the heart and blood vessels

Cardiovascular Diseases (CVDs) refer to a group of disorders affecting the heart and blood vessels, including conditions such as coronary artery disease, hypertension, heart failure, and stroke. These diseases are often caused by atherosclerosis (the buildup of plaque in the arteries), high blood pressure, smoking, diabetes, and other lifestyle factors, and they are a leading cause of morbidity and mortality worldwide.

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community Safety of RU-58841: I talked to the Pharma Company that researched it, Human Clinical Trials, and Potential Reasons for Discontinuation

in Research/Science 140 upvotes 1 year ago

The safety and effectiveness of RU-58841 as a hair loss treatment, with some users reporting side effects like chest pains, while others had positive results. The original research on RU-58841 was likely stopped due to financial issues, not safety concerns.

community Have to share with you guys. I’m 41. Can’t believe this is actually working. I was bald as hell 1 year ago. I have a ways to go still. Pics of all products included. Most purchased on Amazon

in Progress Pictures 1315 upvotes 6 months ago

A user shared their successful hair regrowth using a combination of derma stamping, Retinol, Minoxidil, Dutasteride, and RU58841, with no side effects. Others discussed their varied experiences with these treatments, including concerns about potential side effects like heart issues and sexual dysfunction.

community Is there a consensus on RU these days? Pyril turned out to be a bust right?

in Research/Science 17 upvotes 7 months ago

The conversation discusses the effectiveness and safety of hair loss treatments, specifically RU58841 and Pyrilutimide (Pyril), with users sharing that Pyril was no more effective than a placebo and expressing concerns about the safety of RU58841 based on personal experiences and the lack of pharmaceutical interest.

community Low dose oral minoxidil, any success stories?

in Minoxidil 13 upvotes 1 month ago

Low-dose oral minoxidil shows mixed results, with some users experiencing hair regrowth and others seeing no significant change. Finasteride is also commonly used, often in combination with minoxidil, and is generally considered effective with a low rate of side effects.

community "Things are now in motion that cannot be undone." First Fin tablet taken today.

in Finasteride/Dutasteride 102 upvotes 3 months ago

A user started taking finasteride due to increased hair shedding and sought advice on coping with the anxiety of starting the treatment. Responses included personal experiences with finasteride, minoxidil, and tips for integrating the medication into daily routines.

community Comparison of options: topical vs medication

in Female 1 upvotes 4 months ago

A user diagnosed with AGA is seeking advice on hair loss treatments, comparing topical Minoxidil, Spironolactone, and Finasteride to oral medications and natural methods like dermastamping, PRP, and LED light. They are concerned about side effects and effectiveness, especially given their existing fatigue.

community For those of you applying Pyrilutamide, what's your plan B?

in Treatment 6 upvotes 11 months ago

The user switched from Pyrilutamide to RU58841, changed their Minoxidil solution, and continued using low-dose Finasteride, derma rolling, and specific shampoo. They asked others about their plans after Pyrilutamide's disappointing results.

community There’s a new tooth regrowing drug but still there’s struggles with hair 😂

in Research/Science 117 upvotes 5 months ago

A new drug can regrow teeth, but hair loss treatments like Minoxidil, finasteride, and RU58841 are still being developed. Users express hope for future advancements and discuss the importance of mental health and the potential profitability of hair loss solutions.

community switched from topical to oral minoxidil (topical mixed with water) 3 months ago and aside from being much easier i’ve also had much more density overall. My results aren’t even finished yet!

in Progress Pictures 2 years ago

This user discussed using oral minoxidil as a hair loss treatment, and was cautioned against mixing topical minoxidil with water and drinking it due to potential side effects and risks. Other users shared their concerns about the dangers of self-prescribing medications without consulting a doctor.

community Can RU58841 stop hairloss for a long time?

in Research/Science 11 upvotes 10 months ago

A user is considering using RU58841 to treat hair loss and asks if it can be effective for 4-5 years. Some suggest starting with a lower concentration and debate the safety of RU58841 compared to approved drugs like finasteride.

community 2 year progress on fin and minox

in Progress Pictures 1149 upvotes 4 years ago

A user's 2-year experience with Minoxidil and Finasteride as a treatment for hair loss, including the costs involved and potential side effects. Other users shared their experiences and asked questions about their own use of these treatments.

community Why is it "not right" to start off with Dutasteride?

in Finasteride/Dutasteride 60 upvotes 3 months ago

The conversation discusses whether it's better to start hair loss treatment with finasteride or dutasteride. Opinions vary, but many suggest starting with finasteride due to its shorter half-life and easier management of side effects, while others argue dutasteride is more effective and has fewer side effects.

community [AMA] 5-Month Progress Report: Dutasteride and Oral Minoxidil Results.

in Minoxidil 73 upvotes 3 years ago

Naepo's 5-month progress report detailing their journey of treating male pattern baldness with dutasteride and oral minoxidil, which has already resulted in an encouraging improvement in hair density. Others have responded with appreciation for the thorough report and asked further questions about Naepo's educational background.

community My hair after 3 steroid cycles

in Progress Pictures 24 upvotes 4 months ago

A user shared their hair progress after three steroid cycles, using 5% minoxidil and 100mg RU58841 daily. They are considering a hair transplant due to paranoia about shedding.

community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 7 months ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

community Kintor has released an investor relations memo regarding Chinese Phase III trials for Pyrilutamide

in Update 54 upvotes 11 months ago

Kintor's Pyrilutamide (KX-826) showed hair growth in Chinese Phase III trials but did not significantly outperform placebo. The treatment was safe with no major adverse reactions reported.

community An Update After 7 Years of Finasterise

in Progress Pictures 126 upvotes 1 week ago

The user shared their positive experience with finasteride for hair loss over seven years, noting it stopped hair recession and maintained their hairline. They also mentioned using minoxidil irregularly and experiencing a lower sperm count but no erectile dysfunction.

community RU-58841 Lung Disease Possibility | Chest pain, "heart issues", etc

in Treatment 24 upvotes 8 months ago

Some users of RU-58841 report cardiovascular symptoms like heart palpitations and chest tightness, which may be linked to its metabolites causing lung disease. The safety of RU-58841 is uncertain due to lack of long-term data and concerns about product purity, especially from gray market sources.

community A Different Take on Curing MBP

17 upvotes 5 years ago

Addressing hair loss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.

community Finasteride, also known as Propecia or Proscar, treats male pattern baldness and enlarged prostate in millions of men worldwide. But a new study suggests the drug may also provide a surprising and life-saving benefit: lowering cholesterol and cutting the overall risk of cardiovascular disease.

in Research/Science 531 upvotes 8 months ago

The conversation discusses the potential benefits of finasteride (Fin) for lowering cholesterol and reducing cardiovascular disease risk, with users sharing personal experiences and opinions on the medication's effects on health and hair loss. Some users report positive changes in cholesterol levels after taking finasteride, while others are skeptical or joke about its effects.

community My experience with Pyrilutamide

in Update 3 upvotes 7 months ago

The user experienced a slight decrease in hair shedding and scalp itch, and reduced sebum production using Pyrilutamide, but stopped due to chest pain, breathing difficulties, and heart issues. They felt normal a week after discontinuing and doubted FDA approval for the drug.

community Does vitamin D deficiency actually cause hair loss? Has anyone actually grew back hair after fixing vitamin d levels?

in Chat 51 upvotes 1 week ago

Vitamin D deficiency can contribute to hair loss, but it is not the sole cause, and supplementation may not always resolve the issue. Treatments like finasteride and minoxidil are recommended for hair regrowth, with vitamin D and other supplements providing additional support.

community I spoke to the Guy who did the Ru58841 (PSK-3841) research

in Research/Science 293 upvotes 3 years ago

The conversation discusses RU58841, a compound for hair loss treatment, which was found to be effective in a 6-month trial but was not pursued due to financial issues or marketability concerns, not safety. Some users are considering crowdfunding to release the research data, while others discuss personal experiences and safety concerns with RU58841.

community We all regret not acting on hair loss sooner. What is something else we can prevent if we act now?

in Chat 94 upvotes 10 months ago

The conversation discusses the importance of early action in various aspects of life such as healthy eating, skincare, fitness, sleep, financial planning, and career development to prevent future health issues, regret, and financial hardship. Specific treatments mentioned include using sunscreen and tretinoin for anti-aging skincare.

community Anyone switch topical minoxidil to oral and stay on it for over a year?

in Minoxidil 11 upvotes 11 months ago

Someone switched from topical minoxidil to oral minoxidil and found it more effective and convenient, reporting improvements in hair, eyebrows, eyelashes, and beard without scalp issues. They are seeking long-term experiences from others who made the same switch.

community Listen to anyone besides your Mom while fighting hair-loss

in Satire 464 upvotes 4 years ago

Hair loss treatments, with people sharing their experiences of trying to get help from family members and how genetics can affect the severity of hair loss. Treatments mentioned include finasteride, minoxidil, RU58841, scalp massage, whey protein and bleaching.

community It’s crazy how it’s 2018 and the only hair loss treatments we have feature undesirable side effects and/or aren’t even effective for many people.

136 upvotes 6 years ago

Hair loss treatments, including minoxidil, dermarolling, finasteride, dutasteride, hair transplants, hair systems, and shaving the head. The conversation covers various opinions on these treatments and mentions possible side effects as well as alternatives like wigs, vitamins, and lifestyle changes. The post expresses disappointment that there has been no major breakthrough in the field of hair loss treatments despite decades of research.

community TRT. Pyrilutamide. Ru58841. Help

in Treatment 3 upvotes 7 months ago

A 30-year-old man experienced significant hair loss after starting testosterone replacement therapy (TRT), which did not improve with daily finasteride and minoxidil. He is considering restarting TRT and is seeking advice on using pyrilutamide or RU58841 to prevent further hair loss.

community What's "wrong" with oral minoxidil, exactly?

in Minoxidil 173 upvotes 1 week ago

Oral minoxidil can boost hair growth but may cause side effects like heart palpitations and increased body hair. Many prefer topical minoxidil due to fewer side effects.

community I am putting my hair loss treatment on hold until my mental health is better.

in Update 21 upvotes 1 month ago

OP is pausing hair loss treatments to focus on mental health due to anxiety and side effects from RU58841. They plan to try topical finasteride and minoxidil after recovering from pneumonia.