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GlossaryBreast Development

process where mammary glands form and mature in females

Breast development, also known as mammogenesis, is the process by which the mammary glands form and mature, typically occurring in stages throughout a female's life. This process begins in utero, continues through puberty with the influence of hormones like estrogen and progesterone, and further changes occur during pregnancy and lactation. Understanding this process is crucial for both medical professionals and individuals monitoring normal growth patterns or diagnosing potential issues.

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community Has anyone tried Topical oxytocin?

in Treatment 8 months ago

A user reported less hair shedding using melatonin spray and is considering trying topical oxytocin or estrogel for hair growth, but is concerned about potential side effects like breast development. Topical oxytocin has been found to promote hair growth by increasing growth factors.

community FtM: "Aggressive Regemin - Recovery From Norwood-6.5" Minoxodil/Estradiol valerate/Spironolactone. (What will happen in the worst case if CIS male go this way for a year?)

in Progress Pictures 54 upvotes 3 years ago

User "Ant1pal" shares progress pictures of hair regrowth using Minoxidil, Estradiol valerate, and Spironolactone. Users discuss potential side effects and the possibility of localizing estrogen to hair follicles for better treatment.

community 5 months on Spiro and 6 weeks on oral Monoxidil. Beyond thrilled with the results so far

in Female 190 upvotes 4 years ago

Treatments for hair loss, specifically the use of Spironolactone (Spiro) and oral Minoxidil, as well as Finasteride and RU58841.

community Everyone seems to be looking for an antiandrogen as an add on. But what about Estradiol & its derivatives ( excluding the low concentraion alfatradiool ) being used. Anyone has an experience with this ? Anything that won't cause feminization in the process ?

in Chat 6 upvotes 2 months ago

The conversation discusses using estradiol and its derivatives for hair loss without causing feminization. Users mention alternatives like alfatradiol, topical 17b-Estradiol, and DIM (Diindolylmethane).

community Gyno & testoterone level

in Finasteride 282 upvotes 5 months ago

Switching from finasteride to dutasteride and back to finasteride led to gynecomastia and fatigue, likely due to hormonal imbalances. Suggested treatments include Tamoxifen, Raloxifene, or low-dose Anastrozole, with a recommendation to test testosterone and estradiol levels.

community Extreme regimen and still miniaturized hairs. AGA is just impossible to beat.

in Insane 35 upvotes 1 year ago

A user's extreme regimen for hair loss, which includes taking oral and topical medications such as minoxidil, dutasteride, cyproterone acetate and bicalutamide, but still experiencing miniaturization. Suggestions were made to try other treatments such as RU58841 and Pyrilutamide, while also considering mental health treatment and advice on lookmaxxing.

community 2 months of difference with estradiol and spiro (4 months total w/ estradiol & spiro; 4 years of minoxidil and finasteride) (you should not take estradiol or spiro if you look manly and want to continue looking manly)

in Transgender 115 upvotes 1 month ago

Hair regrowth using estradiol, spironolactone, minoxidil, and finasteride, showing significant improvement over four years. HRT is not advised for cis men solely for hair loss due to feminizing effects.

community Well… I Did It. Estrogen Saved My Hairline

in Transgender 720 upvotes 2 months ago

OP transitioned and used Spironolactone, Estradiol Valerate, Minoxidil, and dermarolling, resulting in significant hair regrowth. They advise this method may not be suitable for cis men.

community Just popped my first fin, excited as hell!

in Finasteride/Dutasteride 154 upvotes 6 months ago

A user shared their excitement about starting finasteride for hair loss after trying various ineffective methods. Other users discussed their experiences with finasteride, including shedding phases and side effects, with one mentioning using topical finasteride and minoxidil.

community Just had this wild thought come into my head.

in Satire 403 upvotes 9 months ago

The conversation is about the debate over the existence of Post-Finasteride Syndrome (PFS) and its symptoms, with some users skeptical about PFS and others discussing side effects like erectile dysfunction and gynecomastia from hair loss treatments like finasteride. Specific treatments mentioned include finasteride, viagra, and a joke about using a popsicle stick for erectile support.

community Testosterone and hair loss seeming irrelevance

in Research/Science 81 upvotes 1 year ago

The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

community Just found a little hard lump under my left nipple, it’s over

in Finasteride/Dutasteride 12 upvotes 4 months ago

A user experienced a hard lump under their nipple and increased hair loss after four months of finasteride. They are concerned about the lump and plan to stop the treatment.

community My DHT levels have increased after taking 0.25mg Fin for 47 days!

in Finasteride/Dutasteride 184 upvotes 2 weeks ago

A user experienced increased hair shedding and unchanged DHT levels after taking 0.25mg of finasteride for 47 days, leading them to increase the dose to 0.5mg. Others discussed varying experiences with finasteride, minoxidil, and the importance of measuring scalp DHT.

community Can anyone confidently say their erections are the same on fin ?

in Chat 240 upvotes 5 months ago

The conversation discusses the impact of finasteride on sexual function, with many users reporting reduced libido and weaker erections despite continuing the treatment to prevent hair loss. Some users suggest checking hormone levels or switching to different dosages or treatments like dutasteride, while others share mixed experiences regarding the severity of side effects.

community TRT. Pyrilutamide. Ru58841. Help

in Treatment 3 upvotes 8 months ago

A 30-year-old man experienced significant hair loss after starting testosterone replacement therapy (TRT), which did not improve with daily finasteride and minoxidil. He is considering restarting TRT and is seeking advice on using pyrilutamide or RU58841 to prevent further hair loss.

community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

in Research/Science 123 upvotes 11 months ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

community A Different Take on Curing MBP

16 upvotes 5 years ago

Addressing hair loss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.

community Increased adipose tissue (being overweight) in males may increase likelyhood of finasterde side effects

in Research/Science 29 upvotes 2 months ago

Being overweight may increase finasteride side effects due to higher aromatase activity converting testosterone to estradiol. Maintaining a healthy weight could reduce these side effects.

community No, Finasteride as a treatment for MPB was not an "accident"

in Research/Science 105 upvotes 3 years ago

Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.

community Solving Hair Loss with Research at MIT

in Research/Science 589 upvotes 1 month ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

community Why is nobody studying the difference between donor and balding hair?

in Chat 89 upvotes 5 months ago

The conversation discusses why the difference between donor and balding hair isn't studied more to find a cure for hair loss. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Male pattern baldness, and mental health

in Finasteride/Dutasteride 330 upvotes 9 months ago

A 48-year-old man has been using minoxidil for 15 years and considered finasteride but stopped due to potential side effects. He is concerned about his mental health and the impact of hair loss on self-image, and he encourages support among men experiencing hair loss.

community 35 MtF | 16 Months | Minoxidil + Dutasteride + Microneedling + Exosomes. Note that since I'm early in my transition (and I was coming from a bald state), I still have short hair. Very few MtF progress pictures here, I figure this might help some of you.

in Transgender 127 upvotes 11 months ago

A 35-year-old transitioning female (MtF) shared her hair regrowth journey using Minoxidil, Dutasteride, Microneedling, and Exosomes, starting from a bald state. Commenters discussed the impressive results, skin care routine, and the effects of estrogen on hair and skin.

community Should I start Fin with these blood tests?

in Finasteride/Dutasteride 18 upvotes 1 year ago

A 25-year-old male with normal hormone levels is considering starting finasteride and minoxidil for hair loss but is concerned about high estradiol levels and potential side effects. Responses vary, with some suggesting blood tests before starting treatment and others emphasizing individual tolerance and the importance of consulting a doctor.

community I find it funny a bunch of us on here are on drugs for hairloss and maintain clean/healthy lives and then there’s these mf’s in the 90’s juiced to the gills with steroids and have better hair than all of us lol

in Satire 353 upvotes 1 year ago

The conversation is about the effects of steroids on hair loss. Some users believe that steroids can cause hair loss, while others argue that it depends on individual sensitivity to DHT. There is also discussion about the appearance of balding individuals who use steroids.

community How do we only have two treatments to combat hair loss at this point in time?

in Chat 211 upvotes 1 year ago

The post discusses frustration over the limited and not always effective treatments for hair loss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.

community Scientists have finally found the potential ‘cure’ for baldness

in Research/Science 2 years ago

A new study that found a single chemical could potentially be responsible for hair loss, and the potential to use this discovery to stimulate hair growth. The conversation also includes various treatments such as Minoxidil, Finasteride, RU58841, microneedling, DUT, and Botox for hair loss.

community Residents of Victoria, Australia, sign up for a monoclonal antibody clinical trial – potential cure

in Research/Science 2 years ago

A monoclonal antibody clinical trial for potential hair loss treatments in Victoria, Australia and the discussion of their efficacy. People shared information about similar drugs already on the market, speculated about potential side effects, and discussed how to spread the word about the trial.

community [study analysis] Microdose of topical Finasteride for all the benefits and none of the sides?

in Research/Science 104 upvotes 4 years ago

Topical finasteride as a potential alternative to oral finasteride for reducing DHT levels on the scalp with fewer side effects, and other hair loss treatments such as minoxidil.

community Two Great Articles on NCBI That Summarize What We Actually Know About Finasteride Side Effects

in Finasteride 80 upvotes 5 years ago

The side effects of taking finasteride as a treatment for hair loss, with particular focus on its sexual and psychiatric side effects; research has indicated that there are high and low outliers in terms of prevalence of sexual side effects, but it is usually between 3-5%, while evidence of lasting sexual side effects comes from lower quality sources.