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GlossaryAndrogenic Side Effects

involve physical changes due to male hormones like testosterone

Androgenic side effects refer to the physical changes and symptoms that occur due to the influence of androgens, which are male hormones like testosterone. These effects can include increased body hair, acne, deepening of the voice, and in some cases, hair loss (androgenic alopecia). These side effects are often seen with the use of anabolic steroids or other medications that affect hormone levels.

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community No side effects on pyrilutamide / KX-826 so far

in Research/Science 209 upvotes 3 years ago

User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.

community Transient and Permanent Effects of Finasteride Use

in Research/Science 154 upvotes 3 years ago

Potential side effects of 5AR inhibitors like finasteride and dutasteride. Users debate risks, benefits, and personal experiences with these hair loss treatments.

community to all people who cannot tolerate anti androgens (loe dose topical fin, pyrilutamide, CB) i am getting desperate, looking for a solution

in Research/Science 13 upvotes 1 year ago

The user tried Minoxidil without success, and Finasteride worked but caused sexual side effects even at a very low dose. They are seeking alternative treatments for hair loss as they cannot tolerate anti-androgens and are also in therapy for mental health.

community Kintor has announced the results for their human Phase I trials of GT20029

in Research/Science 257 upvotes 1 year ago

The conversation discusses the potential of a new hair loss treatment, GT20029, which may prevent hair loss by destroying androgen receptors on the scalp. Users express hope for the treatment's success and speculate on its usage routine, effectiveness, and possible side effects.

community Is this progress or I’m just trippin. Left side was July on fin and topical min, right today a month into dut, ru and starting oral min

in Progress Pictures 70 upvotes 2 years ago

User reports progress in hair loss treatment using finasteride, topical minoxidil, dutasteride, RU58841, and oral minoxidil. Positive results include thicker, darker hair and improved hairline.

community Is this broscience? From More Plates, More Dates

in Research/Science 22 upvotes 8 months ago

The conversation discusses whether finasteride's reduction of DHT and increase in scalp testosterone contribute to hair follicle miniaturization. Some participants argue testosterone does not cause miniaturization, while others suggest that even with reduced DHT, other androgens like testosterone may still contribute to hair loss.

community I find it crazy how some people like this bloke have 0 DHT sensitivity. He is on grams of anabolic steroids and has a full, thick head of hair. I wish all of on here had this guys hair genes lol

in Satire 443 upvotes 1 year ago

The conversation is about hair loss and the possibility of maintaining a full head of hair while using anabolic steroids. Some users believe that having good hair genes and taking hair loss protocols can help prevent hair loss while on steroids.

community Regrowth from just fin after high stress and SSRI side effects?

in Finasteride/Dutasteride 8 upvotes 3 years ago

A 22-year-old experienced significant hair loss due to high stress, SSRI side effects, and Androgenic Alopecia, and has seen some regrowth after starting finasteride and using ketoconazole shampoo. They are inquiring if continued use of finasteride and stress reduction alone can lead to further hair regrowth.

community A Systemic Review on Topical Marketed Formulations, Natural Products, and Oral Supplements to Prevent Androgenic Alopecia: A Review

in Research/Science 6 upvotes 4 months ago

Topical formulations, natural products, and CAM therapies are being used to treat Androgenic alopecia to avoid side effects of Finasteride and Minoxidil. The review covers various low-risk, alternative treatment options.

community spironolactone vs bicalutamide What is the difference between them for androgenic alopecia for women?

in Female 8 upvotes 2 years ago

Hair loss discussion involves spironolactone and bicalutamide for women's androgenic alopecia. Focus on effectiveness and side effects.

community Two Great Articles on NCBI That Summarize What We Actually Know About Finasteride Side Effects

in Finasteride 80 upvotes 5 years ago

The side effects of taking finasteride as a treatment for hair loss, with particular focus on its sexual and psychiatric side effects; research has indicated that there are high and low outliers in terms of prevalence of sexual side effects, but it is usually between 3-5%, while evidence of lasting sexual side effects comes from lower quality sources.

community Aromatise inhibitor for finasteride-estrogen side effects?

in Finasteride/Dutasteride 6 upvotes 2 years ago

A user experienced mild side effects from 0.5mg finasteride daily, including increased estradiol and minor gynecomastia. They are considering taking a low dose of exemestane to reduce estrogen levels.

community Increased adipose tissue (being overweight) in males may increase likelyhood of finasterde side effects

in Research/Science 29 upvotes 2 months ago

Being overweight may increase finasteride side effects due to higher aromatase activity converting testosterone to estradiol. Maintaining a healthy weight could reduce these side effects.

community Massive study on finasteride side effects released

in Finasteride/Dutasteride 83 upvotes 1 year ago

The release of a study on 5a-reductase inhibitors (finasteride and dutasteride) which showed an increased risk of depression, dementia, decreased libido, and reduced semen load as potential side effects; discussion around other forms of hair loss treatments such as topical minoxidil, RU58841, or opting to accept baldness; and advice to consider professional help for deeper issues related to hair loss.

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

in Finasteride/Dutasteride 191 upvotes 2 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

community Trying to understand finasteride side effects and post finasteride syndrome

in Finasteride/Dutasteride 74 upvotes 4 years ago

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

community is my dermatologist good or bad?

in Chat 1 upvotes 4 months ago

The dermatologist diagnosed androgenic alopecia and prescribed minoxidil and a shampoo for dandruff, avoiding finasteride due to side effects. The user questions the dermatologist's approach and considers seeking a second opinion due to concerns about the lack of a physical scalp check initially.

community There are no new treatments as of now.

in Chat 2 years ago

Treatments for androgenic hair loss, including the use of finasteride, minoxidil, nizroal and microneedling/dermarolling. Side effects are discussed and it is noted that while there are tradeoffs to taking medications, they are generally safe and effective.

community An argument for why we should take topical Dutasteride seriously

in Research/Science 85 upvotes 3 years ago

Topical Dutasteride may halt hair loss and effectively treat androgenic alopecia. Combining low-dose oral Dutasteride with topical application could maximize regrowth and minimize side effects.

community Just to show you the superiority of dutasteride over finasteride (it's huge)

in Research/Science 58 upvotes 4 months ago

Dutasteride is shown to be significantly more effective than finasteride for treating male androgenic alopecia. Users discuss the difficulty of obtaining dutasteride in some countries and share personal experiences with its effectiveness and side effects.

community IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia

in Research/Science 13 upvotes 1 week ago

IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.

community How to keep taking finasteride after getting gynecomastia as a side effect (Full guide and 4 year search complete).

in Finasteride/Dutasteride 52 upvotes 2 years ago

User experienced gynecomastia from finasteride and found a solution using liposomal topical finasteride. This method minimizes side effects and is effective for hair loss treatment.

community The no BS guide to saving your hair without finasteride (improvement in 90% of patients in the study) with a low side effect profile or improvement in 100% of patients but a higher side effect profile and increased dosage. The future is here?

in Minoxidil 92 upvotes 4 years ago

Hair loss treatments, specifically the use of oral minoxidil in combination with micro-needling. Oral minoxidil has been found to improve hair density in 90% of patients with a low side effect profile, but using 5mg per day can result in higher side effects including hypertrichosis and edema. Other treatments mentioned include finasteride and RU58841.

community Post Finasteride Syndrome, A dangerous lie.

in Chat 142 upvotes 8 months ago

A user initially had side effects from finasteride, attributed them to anxiety and the nocebo effect, and after resuming the drug, experienced positive effects and now warns against misinformation about Post Finasteride Syndrome.

community Concerns about CosmeRNA safety mechanisms

in Treatment 3 upvotes 1 year ago

Concerns about CosmeRNA safety mechanisms and potential side effects. Discussion includes comparisons to Fluridil and questions about nanoparticle specificity and siRNA stability.

community Discussion on Finasteride and life.

in Chat 163 upvotes 3 weeks ago

Finasteride can aid hair regrowth but may cause side effects like depression and sexual dysfunction. Users discuss experiences with finasteride, minoxidil, and RU58841, highlighting varied responses and the importance of informed treatment choices.

community My dermatologist uses oral minox and dutasteride

in Minoxidil 65 upvotes 2 years ago

Treatments for hair loss and the potential side effects. The user discussed their doctor's advice to take 1.25 mg oral minoxidil and .5 mg dutasteride daily, with a warning that those with heart conditions should not take oral minoxidil. Other users shared their experiences, including taking finasteride and noting the possible overkill of the dosage prescribed by Jirons1's dermatologist.

community Maintaining hair until Breezula without Fin

in Treatment 6 upvotes 4 years ago

A 21-year-old male experienced side effects from topical finasteride and is seeking alternative treatments to maintain hair until Breezula is available. He is considering using minoxidil, Nizoral, micro-needling, and vitamin D supplementation, and may try CB or RU58841 if necessary.

community A warning to those using or thinking about using Dutasteride – Follow-up

in Finasteride/Dutasteride 18 upvotes 3 years ago

The post and conversation are about the long-term side effects of using Dutasteride and Finasteride for hair loss, including issues like raised liver enzymes, high cholesterol, and loss of libido. The user advises regular blood work and careful monitoring for those using these treatments.

community 2Y 5M on dut, ask me anything

in Finasteride/Dutasteride 137 upvotes 2 weeks ago

A user experienced significant hair regrowth using dutasteride without side effects, starting with finasteride and not using minoxidil or dermarolling. They attributed success to a unique genetic response to DHT blockers but did not share their full regimen, frustrating others.