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GlossaryAdrenal Gland Function

regulates stress response and metabolism through hormone production

The adrenal glands are small, triangular-shaped glands located on top of each kidney. They produce hormones like cortisol, adrenaline, and aldosterone, which help regulate metabolism, immune response, blood pressure, and stress response. Proper adrenal gland function is crucial for maintaining homeostasis and responding to physical and emotional stress.

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community I’m 14 years old and I’m losing more hair than my dad. I’ve gone to the doctor 2 times because of this and I’ve received no help. I’m starting to feel like It’s worthless and my hairs gonna look like this forever. I don’t know how anyone could help me but it’s always worth a shot.

in Treatment 3 years ago

A 14 year old who is experiencing hair loss and has not received any help from the doctor, with advice being given to try different doctors, get tested for underlying conditions and intolerances, buzz it short as an option and treatments that could slow down or reverse the hair loss such as minoxidil, finasteride, RU58841 and addressing the cause of the hair loss.

community How I started reversing Male Pattern Baldness naturally ?

in Question 6 upvotes 7 years ago

The user reversed male pattern baldness using a pro-thyroid diet, lifestyle changes, and scalp stimulation exercises, without Minoxidil or Finasteride. They reported reduced dandruff, itchiness, oiliness, and experienced hair regrowth and thickening over 15 months.

community Transient and Permanent Effects of Finasteride Use

in Research/Science 154 upvotes 2 years ago

Potential side effects of 5AR inhibitors like finasteride and dutasteride. Users debate risks, benefits, and personal experiences with these hair loss treatments.

community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

in Progress Pictures 83 upvotes 1 year ago

Treating Seborrheic Dermatitis, a fungal scalp condition which can cause hair loss. Treatments discussed include antifungal shampoos, cold showers, exfoliating the scalp, taking Vitamin D, and stimulating the prostate through the anus.

community Medications that cause extra hair growth

in Research/Science 119 upvotes 10 months ago

The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

community This and ketoconazole 2% life changing

in Ketoconazole 68 upvotes 9 months ago

The post discusses the user's experience with hair loss treatment using finasteride, clobetasol propionate, and ketoconazole shampoo. The conversation warns about the potential side effects of clobetasol, a powerful topical steroid, and emphasizes its short-term usage.

community C’est terrible - at my wits end

in Female 445 upvotes 9 months ago

A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 109 upvotes 5 months ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community When someone posts a scalp tension theory

in Satire 268 upvotes 3 years ago

Hair loss theories discussed include poor blood flow, scalp tension, inflammation, and DHT. Treatments mentioned are massaging scalp, minoxidil, finasteride, and RU58841.

community 1.5 years on fin/min progress pics, thoughts would be great!

in Progress Pictures 69 upvotes 3 years ago

A 42-year-old male shared his 1.5-year hair regrowth progress using 1.25mg finasteride daily and regular doses of minoxidil twice a day, and recently started using the Derminator 2. He also mentioned his battle with cancer and Cushing's syndrome, which affected his weight and hair.

community Anything stronger than DUT out there?

in Finasteride/Dutasteride 14 upvotes 5 months ago

The conversation discusses seeking a stronger treatment than Dutasteride (DUT) for hair loss. Suggestions include combining DUT with RU58841, increasing DUT dosage, and using transgender hormone replacement therapy or testosterone blockers, though some options may have feminizing side effects.

community Anyone remember Breezula, the promising hairloss drug that was perpetually 3 years away? Well, it's available right now as an acme treatment. Can we just directly apply to the scalp?

in Treatment 42 upvotes 3 years ago

The conversation discusses the availability of Breezula, a drug for hair loss, now being sold as an acne treatment, and whether it can be applied to the scalp. Users express skepticism about new hair loss treatments and suggest waiting for FDA approval.

community Currently crushing 3 (5mg) tablets of fin into my topical min. Anyone do the same? If so how much do you add.

in Treatment 186 upvotes 2 months ago

The conversation discusses using crushed finasteride tablets mixed with topical minoxidil for hair loss treatment. Users share their experiences and opinions on the effectiveness and proper concentration of this method.

community If we lose hair because of our sensitivity to DHT, then why are we trying to reduce DHT when our sensitive androgen receptors are the culprit?

in Finasteride/Dutasteride 12 upvotes 2 years ago

The conversation discusses the effectiveness of reducing DHT for hair loss treatment and explores alternative approaches like reducing androgen receptor sensitivity. Specific treatments mentioned include finasteride, dutasteride, pyrilutamide (KX-826), GT20029, and RU58841.

community Injecting stomach fat into the scalp could cure baldness in just six months

in Update 114 upvotes 5 years ago

A potential treatment for hair loss that involves injecting fat into the scalp; the role of testosterone and estrogen in thinning fat tissue under the skin; research on using lard to treat androgenic alopecia, as well as PRP + ACELL/amniotic stem cell treatments; and ongoing clinical trials by doctors involved in the study.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 61 upvotes 10 months ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community No luck with meds, Check your Cortisol.

in Treatment 33 upvotes 1 week ago

Cortisol from stress can cause hair loss. Controlling cortisol levels improved the effectiveness of finasteride for hair regrowth.

community Do any of you guys feel like your 20s have been wasted?

in Chat 184 upvotes 3 months ago

A user expressed frustration about hair loss and its impact on their 20s, mentioning financial struggles and mental health concerns. Responses included advice on positive thinking, self-improvement, and seeking treatment options like Minoxidil and finasteride.

community Clotrimazole a better anti-androgen than Ketoconazole?

in Research/Science 1 upvotes 4 years ago

Clotrimazole may inhibit testosterone better than Ketoconazole. The user considers applying Clotrimazole cream on the scalp for hair loss.

community What do these pictures say about my hair and scalp if anything? Miniaturization, inflammation, etc.?

in Research/Science 74 upvotes 1 year ago

Hair loss and scalp issues, with people discussing possible treatments such as Nizoral shampoo, Minoxidil, neem oil, and finasteride.

community So I was wondering what stack are we on boys? 🤔

in Satire 480 upvotes 1 year ago

Treatments for hair loss, including microneedling, finasteride, minoxidil, dutasteride, RU-58841, pyrilutamide, pumpkin seed oil, rosemary water, orchiectomy, and estrogen.

community When do you think Breezula will be released to the public?

in Chat 31 upvotes 2 years ago

The conversation discusses expectations for the release of Breezula, a new hair loss treatment, and compares it to existing treatments like finasteride. Some believe Breezula could be a game-changer due to fewer side effects, while others await more permanent solutions like hair follicle cloning.

community Pyrilutamide PHASE 2 Results just one months to go. Are you excited???🤩

in Research/Science 96 upvotes 2 years ago

Pyrilutamide, a potential topical treatment for male pattern baldness, and the user's anticipation of its Phase 2 trial results. Several users discussed their experiences with Finasteride and RU58841, while others voiced skepticism about the efficacy of Pyrilutamide.

community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

in Update 38 upvotes 5 years ago

The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

community 5 Month’s progress on Topical FIN, MIN, Topical Dut, Laser Cap

in Progress Pictures 575 upvotes 2 years ago

User "hemantch" shares 5 months progress using topical Fin, Min, topical Dut, and a laser cap for hair loss. Significant regrowth was noticed after 1 month, and the treatments worked well despite being bald for 10 years.

community Mechanism of action of alfatradiol (17 alpha estradiol)

in Research/Science 6 upvotes 2 months ago

The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

community 11-month update. This time wet hair comparison!

in Progress Pictures 108 upvotes 10 months ago

The post discusses an 11-month hair loss treatment journey using dutasteride, minoxidil, nizoral, and 1.5mm derma rolling. The responses inquire about the frequency of derma rolling and express optimism for further progress.

community Has anyone tried Winlevi (a.k.a. Clascoterone or CB-03-01) on their scalp yet?

in Treatment 9 upvotes 2 years ago

The acne medication Winlevi, which contains Clascoterone, is available in the U.S. and may slow down hair loss until a higher concentration treatment, Breezula, is released.

community Smoking – Why Dutasteride may not be working

in Finasteride/Dutasteride 30 upvotes 1 year ago

Dutasteride works for most men, but some may experience worsening due to reasons like shedding, paranoia, non-androgenic alopecia, genetic variations, or smoking. Smoking can increase scalp DHT levels and damage follicles.

community Starting treatment , CB-03-01 , 7.5%

in Treatment 7 upvotes 2 years ago

User asks about CB-03-01 for hair loss treatment and mentions using topical Dutasteride, TRT, and considering mixing CB-03-01 with Fluridil. CB-03-01 is sold at a high price, and user considers trying a lower concentration.