The conversation discusses the absorptiontime of a mixture of Minoxidil, RU58841, and stemoxydine on the scalp, questioning if one hour is sufficient. It is categorized under Finasteride/Dutasteride treatments.
A new topical Dutasteride with 20 times better scalp absorption being developed and tested for release in 2023; use of existing drugs, such as Minoxidil and finasteride; and mesotherapy as an alternative hair loss treatment.
Stevia microneedles increased minoxidil absorption and hair growth in mice. The conversation humorously questions the applicability of these results to humans.
A user discusses a hair loss treatment combining minoxidil and tretinoin, noting it may enhance absorption. Some users express interest and share positive experiences, while others question its effectiveness without medical evidence.
A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.
Apply tretinoin cream first, then minoxidil, as tretinoin can enhance minoxidil absorption. Allow some time between applications to avoid skin irritation.
The conversation discusses a hair loss treatment called "nanoxidil," which is similar to minoxidil but with better absorption. Users are curious about its effectiveness for hair regrowth.
Topical finasteride absorption starts almost instantly, but the exact time needed for full absorption is unclear. Users suggest it may not need to stay on all day.
RU58841 mixed with Minoxidil seems less effective over time, so the user plans to switch to a PG and Ethanol dilution for better results. They also consider using rosemary oil with Minoxidil to enhance RU58841 absorption.
Microneedling for hair loss involves using 0.25-0.5mm needles multiple times a week for Minoxidil absorption and 1.0-1.5mm needles once every two weeks to a month for deep follicle stimulation. One user prefers using 1.5mm needles every two weeks, separate from Minoxidil application days.
Iron supplements can help improve hair thinning and brittle skin, but recovery time varies based on individual factors like ferritin levels and absorption rates. Regular blood tests are recommended to monitor ferritin and iron levels.
The user is concerned about safely using RU58841 around cats and wonders if applying it 2 hours before a shower is as effective as leaving it overnight. The discussion focuses on the absorptiontime and effectiveness of RU58841.
The conversation is about the effectiveness of Minoxidil formulations with different alcohol and propylene glycol (pg) ratios. The user finds that a formulation with 20% pg and 80% ethanol dries faster but is concerned about absorptiontime.
Combining Minoxidil with Finasteride or RU58841 may cause interference, irritation, or reduced absorption. It might be better to apply one topical at a time and wait an hour before applying another.
The conversation is about whether it's safe to use minoxidil with a mix of stemoxydine, RU58841, alfatradiol, and tretinoin at the same time for hair loss treatment. Concerns were raised about the absorption and effectiveness when these treatments are applied together.
Mixing finasteride with minoxidil and RU58841 with stemoxydine for hair loss treatment. Concerns about residue in solutions potentially affecting absorption and stability over time.
User asks if washing hair or using hair fibers after minoxidil dries is okay and if dry scalp means full absorption. Some doctors and sources say 50-75% absorption occurs after an hour.
The conversation discusses whether oily scalp and sebum can hinder the absorption of topical hair loss treatments like Minoxidil and Finasteride, even when using tretinoin. The user is skeptical about the effectiveness of these treatments due to their oily scalp condition.
Maximum serum DHT suppression for finasteride occurs at 8 hours, while for dutasteride, it occurs within 1 to 2 weeks with daily dosing. Dutasteride mesotherapy will be followed by blood tests to check serum DHT changes.
The conversation is about the application timeline for tretinoin and minoxidil. It discusses whether to wait 30 minutes to an hour after applying tretinoin before using minoxidil or to apply tretinoin at night and minoxidil in the morning.
Microneedling with a dermapen using .3mm needles daily is discussed to enhance minoxidil absorption. Some users reuse cartridges for multiple applications, ensuring cleanliness with alcohol.
Effective treatments for hair loss include finasteride, dutasteride, RU58841, and minoxidil. Starting treatment early is important, and users discuss different brands, forms, and side effects.
The conversation is about using distilled water as a solvent for topical finasteride to reduce systemic absorption. The user is considering avoiding ethanol and propylene glycol to achieve this.
A 24-year-old male shared his 9-month hair loss treatment journey, initially using topical finasteride and minoxidil, and recently switching to oral dutasteride and minoxidil. He experienced manageable shedding, noticeable hair density improvement, and plans to consider a hair transplant after 12-18 months on the oral treatment.
Minoxidil is often applied once or twice daily for hair growth, but many find it inconvenient and switch to once daily or oral minoxidil for ease. Some users combine it with finasteride for better results, despite potential side effects.
The user has been using oral finasteride, oral and topical minoxidil, RU58841, and microneedling to treat hair loss, with recent additions of oral dutasteride, GHK-Cu serum, and increased microneedling. They report visible thickening and new hair growth, expecting significant improvement by next June.
Using tretinoin to enhance minoxidil absorption for hair loss treatment. Apply tretinoin, wait 30 minutes, then apply minoxidil; use moisturizer to manage skin reactions.
The user has been using finasteride and minoxidil for 5 years to prevent hair loss and is considering adding dutasteride for regrowth or opting for a hair transplant. Suggestions include trying dutasteride, oral minoxidil, microneedling, and possibly a hair transplant for better results.
The conversation discusses how the absorption rate of topical finasteride varies and is not equivalent to its oral form, with only a small percentage reaching the scalp. It also mentions that minoxidil in high concentrations is used topically because only a small amount is absorbed.
Oral minoxidil is generally more effective than topical minoxidil, despite higher side effect risks. Topical minoxidil can achieve higher bloodstream levels in some individuals, but effectiveness depends on conversion and scalp response.