Search

for
Search:

Glossary11β-Hydroxysteroid Dehydrogenase Type 1

enzyme converting inactive cortisone to active cortisol

11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) is an enzyme that converts inactive cortisone into active cortisol, a hormone involved in stress response, metabolism, and immune function. This enzyme is found in various tissues, including the liver and adipose tissue, and plays a role in conditions like obesity, diabetes, and potentially hair loss due to its influence on local cortisol levels.

Related Terms

Sort by

Community Join

30 / 729 results

community The theory that explains everything. Please help me make this big!

in Research/Science 2447 upvotes 3 years ago

The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

community "but it will hurt my gains bro"

in Satire 1295 upvotes 1 month ago

The conversation humorously discusses hair loss treatments like Minoxidil, Finasteride, and Dutasteride, and their effects on hair and muscle gains. Users debate effectiveness and side effects, mixing scientific approaches with jokes.

community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

in Research/Science 92 upvotes 2 years ago

The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

community My Experience and a Discourse on "DUPA"

in Treatment 9 upvotes 5 months ago

The user discusses their hair loss experience, exploring various hypotheses including thyroid levels, vitamin D, DHEA, nutritional deficiency, diabetes, seborrheic dermatitis, lack of nutrition to hair follicles, chronic inflammation, female pattern hair loss causes, cortisol, and prolactin levels. They are currently using finasteride, beta-sitosterol, and have tried topical dutasteride and microneedling therapy.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

in Technology 107 upvotes 1 month ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community Another Creatine + Finasteride Experiment With Bloodwork

in Update 282 upvotes 2 years ago

Experimenting with the effects of creatine and finasteride on DHT levels, as well as a discussion regarding the potential link between creatine supplementation and hair loss.

community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

in Treatment 46 upvotes 5 months ago

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

community Just found out I am Vitamin D deficient

in Treatment 58 upvotes 3 years ago

A user found out they are vitamin D deficient and was prescribed high-dose vitamin D supplements, asking if others had similar experiences and if it improved their hair. Some shared improved mood and testosterone levels after treatment, while another combined vitamin D supplements with finasteride due to family history of baldness.

community Solving Hair Loss with Research at MIT

in Research/Science 595 upvotes 3 weeks ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

community FINASTRIDE and switch to DUTASTRIDE, my experience

in Progress Pictures 136 upvotes 2 months ago

The user shared their experience with Finasteride and Dutasteride for hair loss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.

community Why do people feel the need to comment on my hair when they know there's nothing I can do about it?

in Chat 72 upvotes 6 months ago

A 28-year-old started using finasteride and minoxidil for hair loss and is frustrated by insensitive comments from others about his balding, which is a sensitive topic for him. People, including a girl he's seeing, have made hurtful remarks, and the conversation includes discussions on societal double standards and advice to ignore such comments and focus on self-improvement.

community Try to find picture of Justin Bieber without a hat in the last two years - challenge impossible

in Chat 164 upvotes 6 months ago

The conversation discusses Justin Bieber's apparent hair loss and the public's reaction to it, with some speculating he's had a hair transplant or is avoiding hair loss medications due to side effects or medical conditions. There's also mention of his past comments on Prince William's balding and the irony of his current situation.

community Creatine's effect on Hair Loss and DHT

in Research/Science 100 upvotes 8 months ago

A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

community Bald groom beaten over fake hair.

in Satire 881 upvotes 1 year ago

A bald groom was beaten by the family of the bride for wearing a wig. The conversation discusses the cultural stigma around baldness in India and the consequences of deception in arranged marriages.

community No side effects on pyrilutamide / KX-826 so far

in Research/Science 206 upvotes 3 years ago

User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.

community Hair Remedies that Don't Work for Anybody Seeking Hair Regrowth

in Treatment 7 upvotes 4 years ago

Hair loss treatments discussed include minoxidil, finasteride, and RU58841. Salon products and supplements generally don't work for hair regrowth unless there's a severe nutritional deficiency, while hormonal treatments like estrogen and spironolactone can be effective.

community 1 year results. Fin + Min + Microneedling + tretinoin + ketoconazole

in Progress Pictures 206 upvotes 3 years ago

A user's 1 year progress using a combination of treatments, including Minoxidil BID, finasteride, microneedling, tretinoin, and ketoconazole shampoo, for hair loss. Replies included advice such as to consider switching the strength of minoxidil or getting a shorter haircut.

community Dutasteride takes 1-3 months to work in the scalp. Not weeks. Be careful.

in Finasteride/Dutasteride 41 upvotes 2 months ago

Dutasteride takes 1-3 months to affect scalp DHT levels, not just a week. The prostate absorbs Dutasteride faster than the scalp due to different vascular networks and enzyme densities.

community Results after more than 1.5 years on Finasteride

in Finasteride/Dutasteride 243 upvotes 3 months ago

A user shared their experience with finasteride for hair loss, noting it slowed but didn't stop their hair loss, and they quit after 1.5 years. Suggestions included trying dutasteride, adding minoxidil, and maintaining a healthy lifestyle.

community To the late responders of finasteride. How long did it take to finally see results?

in Finasteride/Dutasteride 219 upvotes 5 months ago

Finasteride can take over a year to show results, with some users seeing significant improvements after 1.5 to 3.5 years. Patience is key, and combining treatments like minoxidil may help.

community 3 month progress! (Min and derma only)

in Is this regrowth? 239 upvotes 1 month ago

The user reported hair regrowth progress using minoxidil and dermapen, considering adding finasteride. Others shared experiences with minoxidil, finasteride, and microneedling, recommending finasteride for long-term results but noting potential side effects.

community Nothing's working, I feel depressed, also hopeless for the first time

in Update 102 upvotes 2 years ago

A user's experience with hair loss treatments, including Finasteride, Minoxidil, Nizoral Shampoo, Rosemary Oil, Vitamin D, Biotin, Vitamin C, Zinc and Dermarolling, that have not been successful over the past 14 months. Other users gave advice on how to cope with the issue, such as exercising, changing mindset, and shaving their head.

community The Golden Hair Regrowth/Loss Prevention Regimen With Results and Explanation

in Treatment 224 upvotes 2 years ago

Hair loss prevention and regrowth regimen includes finasteride, oral minoxidil, stemoxydine, hair growth serum, derma rolling, and ketocanazole shampoo. Users discuss efficacy, safety, and personal experiences with treatments.

community 11 weeks on topical minox/finasteride/microneedle/LLT. Are these good results?

in Is this regrowth? 68 upvotes 3 weeks ago

The user has been using topical minoxidil, finasteride, microneedling, and laser light therapy for 11 weeks to address hair thinning. They report difficulty applying the treatment due to increased hair thickness and are unsure if the results are significant.

community 11 months oral fin + min capsule

in Progress Pictures 224 upvotes 1 month ago

The user has been using a daily capsule containing 1mg finasteride and 2.5mg minoxidil for 11 months, with noticeable regrowth on the crown but minimal improvement on the hairline. They experienced no significant side effects and plan to continue the treatment long-term.

community 11 months progress pictures (24M)

in Progress Pictures 271 upvotes 2 months ago

A 24-year-old shared his 11-month hair regrowth progress using 1mg oral finasteride, Dr. Reddy's Minoxidil + Finasteride 5% topical solution, 2.5 mg oral minoxidil, microneedling, ketoconazole shampoo, and plans to switch to dutasteride and tretinoin. Users praised his progress, discussed hair regrowth strategies, and shared personal experiences with hair loss treatments.

community 11 month update 1st pic 11 months ago vs today. 2nd pic same timeframe but wet hair. 3rd pic my hair at my worst back in 2020. 4th pic under bright lighting & camera flash. 5th pic hairline. 6th & 7th pic side/back view. 8th pic good hair day.

in Progress Pictures 491 upvotes 2 months ago

The user shared impressive hair regrowth results after 11 months using topical finasteride and minoxidil from HIMS. Many users congratulated the progress and inquired about the application method, brand, and potential side effects.

community 11 months on fin + min. Thoughts?

in Progress Pictures 914 upvotes 2 months ago

A user shared progress pictures after 11 months on finasteride and minoxidil, with intermittent microneedling. The community responded positively, noting significant hair regrowth and encouraging continued treatment.

community 11 months! Intensive and quality treatment. I have to say a big thank you to Minoxidil, and Propecia, and this wonderful sub... I'm 35 years old and my hair is back to 25 years old

in Progress Pictures 133 upvotes 3 months ago

A 35-year-old user shared their 11-month hair loss treatment success using Minoxidil and Propecia, noting their hair looks like it did at 25. Another user asked about the treatment, and the original poster confirmed using Propecia 1 mg and topical Minoxidil twice daily.

community 11 years of alopecia and still good ( for the youngers)

in Progress Pictures 22 upvotes 4 months ago

A user shared their 11-year journey with alopecia, using finasteride, dutasteride, and a hair transplant. They encouraged others not to panic, noting that hair miniaturization can take over 15 years to complete.