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Did you mean Collagen IV?

Glossary Collagen IV

forms part of basement membrane supporting various tissues

Collagen IV, also known as Type IV Collagen, is a crucial protein that forms part of the basement membrane, a thin layer that supports and separates cells in various tissues, including the skin, blood vessels, and organs. It provides structural support and plays a key role in tissue repair and cellular functions, making it essential for maintaining the integrity and function of these tissues.

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research Silk fibroin hydrogel with recombinant silk fibroin/NT3 protein enhances wound healing by promoting Type III collagen synthesis and hair follicle regeneration in skin injury

June 2025 in “Materials Today Bio”

In this study, a silk fibroin hydrogel containing recombinant NT3 was found to promote scar-less wound healing in a mouse skin injury model by enhancing type III collagen expression and inducing hair follicle formation.

research Synergistic Effects of Fractional CO ₂ Laser and Recombinant Humanized Type III Collagen (rhCol III) in Atrophic Acne Scar Treatment: Activation of MAPK Pathway and Enhanced Collagen Remodeling

January 2025 in “Dermatologic Therapy”

In this study, treatment with fractional CO2 laser combined with recombinant humanized type III collagen led to significantly better improvements in atrophic acne scars compared to laser treatment with saline, attributed to collagen upregulation and MAPK pathway activation in human dermal fibroblasts.

research DAB-labelling for collagen type III and PDGFR as control on equine skin sections.

November 2025 in “OPAL (Open@LaTrobe) (La Trobe University)”

In this study, researchers conducted additional IHC staining on equine skin sections and found that collagen type III primarily labels the extracellular matrix, while anti-PDGFR-antibody staining highlights cells with long-shaped processes mainly arranged around hair follicles.

research Type III Collagen Regulates Matrix Architecture and Mechanosensing during Wound Healing

24 citations , September 2024 in “Journal of Investigative Dermatology”

research Eco-engineered recombinant collagen III-PEG hydrogels with curcumin synergy for accelerated skin regeneration: A green crosslinking strategy in wound therapeutics

September 2025 in “International Journal of Biological Macromolecules”

In an animal study with a skin defect model, this research reported that curcumin-loaded hydrogels made from recombinant humanized collagen and an eco-friendly crosslinker enhanced wound repair by promoting angiogenesis, granulation tissue formation, and hair follicle neogenesis, while providing antioxidant benefits.

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community Collagen peptides(powder) i highly recommend

7 upvotes 1 year ago

Collagen peptides are recommended for hair and skin benefits, with users noting improvements in hair and skin health. However, evidence on their effectiveness for hair growth is inconclusive.

community How legit is the skin issues (loss of collagen, wrinkles, under eye cricles etc) with minoxodil?

7 upvotes 8 years ago

Minoxidil may cause facial bloat, wrinkles, and dark circles, with some users experiencing these side effects quickly. Finasteride can cause painful ejaculations and watery semen, but concerns about penis shrinkage are generally unfounded.

community My mother has been losing hair as of recently (she's approaching 60). What are the best supplements and medications I could buy for her to help her with thinning hair, apart from high quality multivitamin, collagen with hyaluronic acid, omega-3s and other basics?

2 upvotes 2 years ago

A user seeks advice on treatments for his mother's hair loss, considering Minoxidil, Finasteride, and shampoos. The mother is being monitored for breast cancer, which may be relevant.

community I use the big 4 to combat but I need to do more

in Minoxidil 3 upvotes 1 year ago

The conversation discusses various hair loss treatments, including Minoxidil, Finasteride, Dutasteride, Ketoconazole shampoo, microneedling, and supplements like collagen, biotin, and vitamins. Users suggest additional treatments like red light therapy, scalp massages, and possibly adding RU58841 or Tretinoin.

community microneedle, any long term users damage?

in Microneedling 35 upvotes 2 years ago

Microneedling is effective for hair growth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.

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Related Terms

Research

research Silk fibroin hydrogel with recombinant silk fibroin/NT3 protein enhances wound healing by promoting Type III collagen synthesis and hair follicle regeneration in skin injury

research Synergistic Effects of Fractional CO ₂ Laser and Recombinant Humanized Type III Collagen (rhCol III) in Atrophic Acne Scar Treatment: Activation of MAPK Pathway and Enhanced Collagen Remodeling

research DAB-labelling for collagen type III and PDGFR as control on equine skin sections.

research Type III Collagen Regulates Matrix Architecture and Mechanosensing during Wound Healing

research Eco-engineered recombinant collagen III-PEG hydrogels with curcumin synergy for accelerated skin regeneration: A green crosslinking strategy in wound therapeutics

Community Join

community Collagen peptides(powder) i highly recommend

community How legit is the skin issues (loss of collagen, wrinkles, under eye cricles etc) with minoxodil?

community My mother has been losing hair as of recently (she's approaching 60). What are the best supplements and medications I could buy for her to help her with thinning hair, apart from high quality multivitamin, collagen with hyaluronic acid, omega-3s and other basics?

community I use the big 4 to combat but I need to do more

community microneedle, any long term users damage?

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learn Overview

learn collagen

learn Hydrolyzed Collagen

learn Marine Collagen Peptides (Nutrafol)

learn Phyto-Collagen Complex (Cécred)

Clinics

Experts

Diego Iida, CRM SP: 143.889

Dr. Joseph F. Greco III, MD

Joseph M. Dai III, MD

Dr. William P. Coleman III, MD