September 2002 in “Research Repository (Kingston University London)” This review discusses strategies for treating hormone-dependent prostate diseases and synthesizes a range of potential 5α-reductase inhibitors, but experimental evaluation of these compounds was not completed.
February 2024 in “Scientific Reports” In this study, cinnamic acid was found to enhance hair growth in human dermal papilla cells and hair follicle organoids by activating oxytocin signaling, suggesting its potential for developing hair growth-promoting products.
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September 2013 in “Expert Opinion on Therapeutic Patents” This review discusses various resveratrol derivative patents for therapeutic, nutraceutical, and cosmetic use, but reports no clinical results and notes that claims of improved efficacy lack trial evidence.
August 2025 in “ACS Omega” This study synthesized and evaluated hydroxycinnamate derivatives for their ability to inhibit human SRD5A1, finding that three compounds showed significant inhibitory activity and low cytotoxicity. Compound 10a notably reduced SRD5A1 protein expression in cells, suggesting potential for nonsteroidal treatment of androgen-related conditions.
January 2023 in “Side effects of drugs annual” This chapter reviews emerging side effects of various nutritional supplements and alternative medicine practices, highlighting potential toxicities and stressing the need for careful identification and management by healthcare professionals.