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      learn Baricitinib

      JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  415 upvotes 8 months ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community 6 months, no progress on fin and min oral. Male 25

      in Progress Pictures  33 upvotes 2 weeks ago
      A 25-year-old male has been using oral finasteride and minoxidil for six months without noticeable progress in hair regrowth and is considering switching to dutasteride or a hair transplant. Users suggest giving the treatment more time, adding microneedling, and possibly using topical minoxidil.

      community My Theory Of Androgenic Alopecia

      in Research/Science  17 upvotes 3 weeks ago
      Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

      community Fresh off the press: Dutasteride may cause chronic infertility

      in Research/Science  643 upvotes 8 months ago
      Dutasteride may cause chronic infertility by reducing semen volume and motility, with concerns about irreversible prostate fibrosis. Users consider switching to finasteride or using treatments like minoxidil and microneedling, weighing hair preservation against fertility.