research Cholesterol Homeostasis: Links to Hair Follicle Biology and Hair Disorders
Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
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research Cholesterol Homeostasis in Hair Follicle Keratinocytes Is Disrupted by Impaired ABCA5 Activity
Impaired ABCA5 activity disrupts cholesterol balance in hair follicle cells, affecting hair growth.
research Short-Term Diabetes in the Brain: Effects on Neuroactive Steroids, Cholesterol Homeostasis, and Mitochondrial Functionality
Short-term diabetes can cause changes in brain steroids, cholesterol balance, and mitochondrial function.
research Disrupted Cholesterol Biosynthesis and Hair Follicle Stem Cell Impairment in the Onset of Alopecia
Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.
research Cholesterol Promotes Hair Growth by Activating Sympathetic Nerves and Enhancing Hair Follicle Stem Cell Proliferation
Cholesterol helps hair grow by activating nerves and boosting hair follicle stem cells.
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5 / 133 resultscommunity Bile Acid-Mediated DHT Dysregulation Hypothesis
Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.
community Finasteride is Good for Heart Health!
Finasteride, a hair loss and prostate drug, may also benefit heart health. Some users discuss the potential negative effects of DHT on the heart and the balance between hair loss treatments and heart health.
community A warning to those using or thinking about using Dutasteride – Follow-up
The post and conversation are about the long-term side effects of using Dutasteride and Finasteride for hair loss, including issues like raised liver enzymes, high cholesterol, and loss of libido. The user advises regular blood work and careful monitoring for those using these treatments.
community Why hasn’t anyone made a "DHT sponge" biologic yet???
The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.
community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders
Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.