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GlossaryChlormadinone Acetate

synthetic hormone used in contraceptives and hormone therapy

Chlormadinone Acetate (CMA) is a synthetic progestin, a type of hormone similar to the natural hormone progesterone. It is commonly used in hormonal contraceptives and hormone replacement therapy to regulate menstrual cycles, treat endometriosis, and manage symptoms of menopause. Additionally, it has anti-androgenic properties, which means it can help reduce the effects of male hormones, making it useful in treating conditions like acne and hirsutism (excessive hair growth).

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research Reactions and Side Effects of Ovulation Inhibitors on the Skin

January 1978 in “PubMed”

Oral contraceptives can affect skin and hair, improve acne, but may cause pigmentation, dermatitis, and other conditions.

research Use of Cyproterone Acetate in the Treatment of Acne, Hirsutism, and Virilism

232 citations , June 1975 in “Journal of Steroid Biochemistry”

Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.

research Profile of the Progesterone Derivative Chlormadinone Acetate: Pharmacodynamic Properties and Therapeutic Applications

33 citations , January 2009 in “Contraception”

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

Clinical, Hormonal and Metabolic Parameters in Women With PCOS Using Different Combined Oral Contraceptives (Containing Chlormadinone Acetate Versus Drospirenone)

research Clinical, Hormonal and Metabolic Parameters in Women With PCOS Using Different Combined Oral Contraceptives (Containing Chlormadinone Acetate Versus Drospirenone)

25 citations , October 2019 in “Journal of Endocrinological Investigation”

Both types of oral contraceptives improved symptoms and hormone levels in women with PCOS.

research Effectiveness of Ethinylestradiol/Chlormadinone Acetate in Treating Dermatological Conditions Related to High Androgen Levels

13 citations , September 2011 in “American Journal of Clinical Dermatology”

The oral contraceptive ethinylestradiol/chlormadinone acetate is effective in reducing acne and improving other skin conditions related to high androgen levels.

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