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analyzes protein-DNA interactions using chromatin immunoprecipitation and sequencing

ChIP-seq, short for Chromatin Immunoprecipitation Sequencing, is a powerful technique used to analyze protein interactions with DNA. By combining chromatin immunoprecipitation with next-generation sequencing, researchers can identify the binding sites of DNA-associated proteins, such as transcription factors, across the entire genome. This method is crucial for understanding gene regulation and epigenetic mechanisms.

Related Terms

• Chromatin Immunoprecipitation
• Next-Generation Sequencing
• Epigenetics