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Did you mean immune checkpoint blockade?

GlossaryImmune Checkpoint Inhibitors (immune checkpoint blockade)

block proteins that prevent immune cells from attacking cancer

Immune Checkpoint Inhibitors (ICIs) are a type of cancer treatment that work by blocking proteins used by cancer cells to evade the immune system. By inhibiting these checkpoints, such as PD-1, PD-L1, and CTLA-4, ICIs enable the immune system to better recognize and attack cancer cells.

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research A Comparative Analysis of Immune Privilege in Pregnancy and Cancer in the Context of Checkpoint Blockade Immunotherapy

16 citations , March 2018 in “Seminars in Oncology”

The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.

research The Role of Lymphocytes in the Development and Treatment of Alopecia Areata

60 citations , September 2015 in “Expert Review of Clinical Immunology”

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

research Nivolumab-Induced Alopecia Areata: A Case Report and Literature Review

10 citations , January 2021 in “Annals of dermatology/Annals of Dermatology”

Nivolumab can cause hair loss as a rare side effect.

research Cutaneous Toxicity as a Predictive Biomarker for Clinical Outcome in Patients Receiving Anticancer Therapy

32 citations , May 2018 in “Journal of the American Academy of Dermatology”

Skin reactions from cancer treatments might predict how well the treatments work.

research Immune Checkpoint Inhibitor-Related Alopecia: Insight into the Pathophysiology Using Non-Invasive Diagnostic Techniques

6 citations , January 2019 in “Journal of dermatology”

Immune checkpoint inhibitors used in cancer therapy can cause hair loss, and understanding this can help manage the side effect.

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community 6th Month Checkpoint! There is progress (I think?)

in Progress Pictures 29 upvotes 1 year ago

The conversation discusses a user's six-month progress in treating hereditary hair loss using a regimen that includes minoxidil, finasteride, dutasteride, and other medications. Opinions vary on the effectiveness and logic of the treatment, with some users suggesting additional methods like microneedling.

community Hair loss journey - progress check & questions

in Progress Pictures 1 upvotes 2 months ago

The user shared their hair loss journey, using Minoxidil 2%, Serenoa repens, topical finasteride, a topical antiandrogen, Vitamin D, and lifestyle changes, noting improvements but still seeking more density. They are considering switching to Minoxidil 5% but prefer focusing on finasteride and antiandrogen for better results.

community Oral min 2.5mg / oral fin 1mg / 3.5 months - 25M progress

in Progress Pictures 169 upvotes 9 months ago

A 25-year-old shared progress on hair growth using oral minoxidil 2.5mg, oral finasteride 1mg, and dermarolling over 3.5 months, noting improvements and encouraging others to persist with treatments. Other users discussed their experiences with similar treatments, including topical minoxidil, ketoconazole shampoo, and tretinoin cream, with varying results and side effects.

community 3 months progress , not seeing significant progress.

in Progress Pictures 11 upvotes 2 weeks ago

The user is using oral minoxidil, finasteride, and a dermaroller for hair loss but is not seeing significant progress after three months. Suggestions include continuing treatment for at least a year, considering dutasteride, adding topical minoxidil, or possibly getting a hair transplant.

community My journey so far, what can you guys tell me?

in Is this regrowth? 6 upvotes 5 months ago

The user has been using finasteride since January 2025 and topical minoxidil since July 2024, noticing some regrowth but also thinning on the left side of the hairline. They are considering switching to dutasteride or oral minoxidil for better results.

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