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This letter comments on a randomized controlled trial by Shapiro et al that found no significant benefits of platelet-rich plasma compared to placebo for male androgenetic alopecia, highlighting issues with PRP protocol variations.

This review analyzes studies on autologous platelet-rich plasma for androgenic alopecia, reporting mixed results and highlighting the need for standardized protocols and further research.

This study found that both single- and double-spin PRP preparation methods significantly increased thrombocyte counts and improved hair parameters in males with androgenetic alopecia, with the single-spin method showing a more significant increase in thrombocyte count.

This study found that platelet-rich plasma therapy may effectively improve hair density and related parameters in men with androgenetic alopecia, with results differing based on specific platelet counts.

This study reviews current methods for making and using platelet-rich plasma and fibrin, emphasizing the variability in clinical outcomes due to differences in preparation protocols, and calls for standardized guidelines and large-scale studies for better effectiveness in regenerative medicine.