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GlossaryCD8+ T cells (CD8-positive T cells)

specialized immune cells that destroy infected or cancerous cells

CD8+ T cells, also known as cytotoxic T cells or killer T cells, are a type of white blood cell that plays a crucial role in the immune system. They are responsible for identifying and destroying infected or cancerous cells by recognizing specific antigens presented on the surface of these cells.

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research Vitiliginous Lesions During Contact Immunotherapy for Alopecia in a Patient with Autoimmune Thyroiditis

2 citations, July 2014 in “Our Dermatology Online”

Contact immunotherapy can cause vitiligo in patients with autoimmune conditions.

research Alopecia Areata in a Rhesus Monkey (Macaca Mulatta)

16 citations, April 2007 in “Journal of Medical Primatology”

The monkey's hair loss was due to an autoimmune disease, not genetics.

research Role of Cytotoxic T Cells in Chronic Alopecia Areata

127 citations, January 2000 in “Journal of Investigative Dermatology”

Cytotoxic T cells cause hair loss in chronic alopecia areata.

research Controlled Delivery of T-box21 Small Interfering RNA Ameliorates Autoimmune Alopecia in a C3H/HeJ Mouse Model

69 citations, February 2008 in “The American journal of pathology”

Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.

research Autoimmune Alopecia Areata Due to Thymoma Without Myasthenia Gravis: A Case Report

May 2023 in “Surgical Case Reports”

A woman's hair loss improved after removing a tumor in her thymus gland, suggesting hair loss can be linked to such tumors even without a specific muscle weakness condition.

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