learn Osteopontin signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
research Hyaluronate Fragments Reverse Skin Atrophy by a CD44-Dependent Mechanism 135 citations , December 2006 in “PLoS Medicine” Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.
research Sulfated Hyaluronan-Containing Artificial Extracellular Matrices Promote Proliferation of Keratinocytes and Melanotic Phenotype of Melanocytes from the Outer Root Sheath of Hair Follicles 8 citations , March 2019 in “Journal of Biomedical Materials Research Part A” Sulfated hyaluronan in collagen helps hair follicle cells grow and develop better for skin grafts.
research Signaling by Senescent Melanocytes Hyperactivates Hair Growth 27 citations , June 2023 in “Nature” Senescent melanocytes can boost hair growth by activating hair stem cells.
research Regenerative Hair Pigmentation via Skin Organoids: Adaptive Patterning Mediated by Collagen VI and Semaphorin 3C July 2025 in “Advanced Science” Collagen VI and Semaphorin 3C are important for hair pigmentation and could help treat pigmentation disorders.
research CD44 Expression in Alopecia Areata and Androgenetic Alopecia 5 citations , June 1994 in “Journal of Cutaneous Pathology” No CD44 in alopecia areata, present in normal and androgenetic alopecia.
community The Cure isn't 5 years away; it's already here. in Research/Science 1005 upvotes 11 months ago PP405 is a new topical treatment for hair loss, showing promise in trials but still requires finasteride for maintenance. There is skepticism about its effectiveness and safety, with concerns about needing finasteride to maintain results.