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GlossaryCXCR4 (CD184)

receptor protein involved in immune cell movement and cancer

CXCR4, also known as C-X-C chemokine receptor type 4 or CD184, is a protein found on the surface of certain cells that plays a crucial role in the immune system. It acts as a receptor for a molecule called CXCL12, which helps guide the movement of cells, including immune cells, to sites where they are needed, such as areas of inflammation or injury. This receptor is also involved in the development and progression of various diseases, including cancer and HIV, making it a significant target for medical research and therapeutic interventions.

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Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men

research Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men

139 citations , December 2020 in “Cell Stem Cell”

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Fetal Skin Wound Healing

research Fetal Skin Wound Healing

89 citations , January 2009 in “Advances in Clinical Chemistry”

Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.

Effective High-Throughput Isolation of Enriched Platelets and Circulating Pro-Angiogenic Cells to Accelerate Skin-Wound Healing

research Effective High-Throughput Isolation of Enriched Platelets and Circulating Pro-Angiogenic Cells to Accelerate Skin-Wound Healing

6 citations , April 2022 in “Cellular and Molecular Life Sciences”

Angio PRP speeds up skin wound healing and reduces inflammation.

Dormant Tumor Cells in Ret Transgenic Mouse Melanoma Model and Their Interaction with Memory T Cells

research Dormant Tumor Cells in Ret Transgenic Mouse Melanoma Model and Their Interaction with Memory T Cells

January 2012 in “heiDOK (Heidelberg University)”

Dormant melanoma cells in mice interact minimally with memory T cells due to a suppressive tumor environment.

research Rescuing Key Native Traits in Cultured Dermal Papilla Cells for Human Hair Regeneration

30 citations , November 2020 in “Journal of Advanced Research”

Conditioned medium from keratinocytes can improve hair growth potential in cultured dermal papilla cells.

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