9 citations,
May 2019 in “Medicine” The C-allele and CC-genotype in the PTPN22 gene lower the risk of alopecia areata.
2 citations,
July 2019 in “PLOS ONE” Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.
3 citations,
January 2020 in “Indian Journal of Dermatology” The study investigated the association between Vitamin D Receptor (VDR) gene polymorphisms (Taq-1 and Cdx-1) and Female Pattern Hair Loss (FPHL) in 30 female patients and 30 age-matched healthy controls. It found that certain genotypes and alleles of Taq-1 (CC, TC, T) and Cdx-1 (AA, GA, G) were significantly more prevalent in FPHL patients, increasing disease risk by various folds (Taq-1: 12.6, 2.1, 2.9; Cdx-1: 7.5, 5.2, 5.5). The study concluded that these polymorphisms could be considered risk factors for FPHL, potentially affecting disease persistence by hindering new anagen growth and reducing hair follicle stem cell proliferation. Further research was recommended to confirm these findings.
36 citations,
January 2017 in “Journal of Obstetrics and Gynaecology Research” The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.
7 citations,
October 2019 in “Clinical, Cosmetic and Investigational Dermatology” Certain gene variations in the Vitamin D receptor may increase the risk of chronic hair loss.