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      natural substance from Neem tree with medicinal and pesticidal properties

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      community The mechanism of androgenic alopecia

      in Research/Science  34 upvotes 1 month ago
      DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

      community Summaries of Finasteride Studies

      in Research/Science  20 upvotes 4 months ago
      Finasteride is effective in promoting hair growth and reversing hair miniaturization in men with androgenetic alopecia, with improvements seen in various studies over different durations. Some users report initial side effects like ball ache, which often resolve as the body adjusts.

      community Methods Of Staying Safe On Ru58841 - My 2 Cents

      in Research/Science  22 upvotes 9 months ago
      RU58841 is used topically to prevent hair loss by blocking DHT, with suggestions to drink grapefruit juice, take breaks, avoid microneedling, and use lower concentrations to reduce side effects. Users discuss applying it at night to minimize systemic absorption.

      community Topical melatonin instead of fin

      in Research/Science  7 upvotes 2 years ago
      A 22-year-old man has been using topical melatonin for a year to slow hair loss and it appears to be effective. He's seeking alternatives to finasteride due to potential side effects, and is interested in understanding how melatonin works to prevent hair shedding.