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GlossaryCaveolin-1

protein involved in cell membrane structure and signaling

Caveolin-1 (CAV1) is a protein that plays a crucial role in the formation of caveolae, which are small invaginations on the cell membrane involved in various cellular processes such as signal transduction and endocytosis. It is also important in regulating lipid metabolism and maintaining cellular structure. In the context of hair biology, alterations in Caveolin-1 expression have been linked to conditions like alopecia, where hair loss occurs.

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research How to Diagnose a Lipodystrophy Syndrome

53 citations, June 2012 in “Annales d'Endocrinologie”

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

research The Role of Immature and Mature Adipocytes in Hair Cycling

30 citations, December 2018 in “Trends in Endocrinology and Metabolism”

Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.

research Androgen Effects in Mammals

7 citations, January 2003 in “Elsevier eBooks”

Testosterone is crucial for development, growth, and various body functions in mammals.

A Cell Membrane-Level Approach to Cicatricial Alopecia Management: Is Caveolin-1 a Viable Therapeutic Target in Frontal Fibrosing Alopecia?

research A Cell Membrane-Level Approach to Cicatricial Alopecia Management: Is Caveolin-1 a Viable Therapeutic Target in Frontal Fibrosing Alopecia?

4 citations, May 2021 in “Biomedicines”

Targeting the protein Caveolin-1 might help treat a type of scarring hair loss called Frontal Fibrosing Alopecia.

Spatial Transcriptomic Analysis of Imiquimod-Treated Mouse Skin Reveals Deregulation of Lipid Raft-Associated Markers Reversible by Caveolin Scaffolding Domain Peptide

research Spatial Transcriptomic Analysis of Imiquimod-Treated Mouse Skin Reveals Deregulation of Lipid Raft-Associated Markers Reversible by Caveolin Scaffolding Domain Peptide

April 2023 in “Journal of Investigative Dermatology”

The research found that a protein called caveolin-1 is reduced in psoriasis, but reintroducing it can help alleviate some psoriasis symptoms.

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