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GlossaryCaveolin-1

protein involved in cell membrane structure and signaling

Caveolin-1 (CAV1) is a protein that plays a crucial role in the formation of caveolae, which are small invaginations on the cell membrane involved in various cellular processes such as signal transduction and endocytosis. It is also important in regulating lipid metabolism and maintaining cellular structure. In the context of hair biology, alterations in Caveolin-1 expression have been linked to conditions like alopecia, where hair loss occurs.

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research Genetic and Histological Correlation Between the Musk Gland and Skin of Chinese Forest Musk Deer

October 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

Musk glands and skin in Chinese forest musk deer are closely related and share many genes.

research A Guide to Studying Human Dermal Adipocytes In Situ

21 citations , March 2018 in “Experimental Dermatology”

The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.

research Three-Dimensional Reconstructions of Mechanosensory End Organs Suggest a Unifying Mechanism Underlying Dynamic, Light Touch

5 citations , March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Dynamic, light touch is sensed through a common mechanism involving Piezo2 channels in sensory axons.

A Cell Membrane-Level Approach to Cicatricial Alopecia Management: Is Caveolin-1 a Viable Therapeutic Target in Frontal Fibrosing Alopecia?

research A Cell Membrane-Level Approach to Cicatricial Alopecia Management: Is Caveolin-1 a Viable Therapeutic Target in Frontal Fibrosing Alopecia?

4 citations , May 2021 in “Biomedicines”

Targeting the protein Caveolin-1 might help treat a type of scarring hair loss called Frontal Fibrosing Alopecia.

Spatial Transcriptomic Analysis of Imiquimod-Treated Mouse Skin Reveals Deregulation of Lipid Raft-Associated Markers Reversible by Caveolin Scaffolding Domain Peptide

research Spatial Transcriptomic Analysis of Imiquimod-Treated Mouse Skin Reveals Deregulation of Lipid Raft-Associated Markers Reversible by Caveolin Scaffolding Domain Peptide

April 2023 in “Journal of Investigative Dermatology”

The research found that a protein called caveolin-1 is reduced in psoriasis, but reintroducing it can help alleviate some psoriasis symptoms.

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