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GlossaryPolycaprolactone

biodegradable polyester used in medical applications

Polycaprolactone (PCL) is a biodegradable polyester with a low melting point, commonly used in medical applications such as sutures, drug delivery systems, and tissue engineering scaffolds. Its biocompatibility and slow degradation rate make it particularly useful for long-term implants and controlled release of medications.

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A Fibrous Hybrid Patch Couples Cell-Derived Matrix and Poly(L-Lactide-Co-Caprolactone) for Endothelial Cells Delivery and Skin Wound Repair

research A Fibrous Hybrid Patch Couples Cell-Derived Matrix and Poly(L-Lactide-Co-Caprolactone) for Endothelial Cells Delivery and Skin Wound Repair

16 citations , December 2018 in “ACS Biomaterials Science & Engineering”

The new patch made of cell matrix and a polymer improves wound healing and supports blood vessel growth.

research Biocomposite Nanofiber Matrices to Support ECM Remodeling by Human Dermal Progenitors and Enhanced Wound Closure

87 citations , August 2017 in “Scientific Reports”

The nanofiber scaffolds improved skin wound healing by supporting cell growth and tissue repair.

Mechanistic Analysis of Human Skin Distribution and Follicular Targeting of Adapalene-Loaded Biodegradable Nanospheres With Insight Into Hydrogel Matrix Influence, In Vitro Skin Irritation, and In Vivo Tolerability

research Mechanistic Analysis of Human Skin Distribution and Follicular Targeting of Adapalene-Loaded Biodegradable Nanospheres With Insight Into Hydrogel Matrix Influence, In Vitro Skin Irritation, and In Vivo Tolerability

17 citations , June 2017 in “Journal of pharmaceutical sciences”

Researchers developed a nanomedicine for acne treatment that delivers medication with less irritation and is non-irritating for oily skin.

research Polymeric Nanoparticles-Embedded Organogel for Roxithromycin Delivery to Hair Follicles

47 citations , July 2014 in “European Journal of Pharmaceutics and Biopharmaceutics”

Scientists created a gel with nanoparticles to deliver medicine to hair follicles effectively.

research Poly (ɛ-Caprolactone)–Chitosan–Poly (Vinyl Alcohol) Nanofibrous Scaffolds for Skin Excisional and Burn Wounds in a Canine Model

11 citations , January 2018 in “IET Nanobiotechnology”

The scaffolds significantly sped up wound healing in dogs and were safe.

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