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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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research The Notch Intracellular Domain Has an RBPj-Independent Role During Mouse Hair Follicular Development
The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.
research Adipose Mesenchymal Stem Cells Combined with Platelet-Rich Plasma Accelerate Diabetic Wound Healing by Modulating the Notch Pathway
Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.
research Notch Signaling in Hair Follicle Development
The Notch signaling pathway is important for hair follicle development and could help create treatments for hair disorders.
research The Disintegrin/Metalloproteinase Adam10 Is Essential for Epidermal Integrity and Notch-Mediated Signaling
Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
research An Accessible Pharmacodynamic Transcriptional Biomarker for Notch Target Engagement
Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.
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5 / 19 resultscommunity Back again with a 17 month update. (Fin/Min doing the heavy lifting, occasional 0.5mm microneedling, and Nizoral for scalp health) - Angles are not identical but whatever - Expecting and hoping to be back to pre-hairloss hairline within 6 months from now.
The conversation is about a user's 17-month progress in treating hair loss using finasteride, minoxidil, occasional 0.5mm microneedling, and Nizoral. The user reports significant hairline recovery and aims to achieve a pre-hair loss hairline within the next 6 months.
community Seems like good progress... Happy with it so far
The user "Segggs" shared their progress with hair loss treatments including 6 months of foam minoxidil, 3 months of finasteride, keto shampoo, and inconsistent microneedling. The replies were positive, with some users commenting on the regrowth in the temple area.
community Il PP405 è molto promettente ma non è l'unico in grado di liberarci dalla iattura
PP405 shows promise in hair loss treatment, but stem cell therapy using adipose-derived stem cells and ATP also successfully reversed androgenetic alopecia in mice. Stem cell therapy is costly, and some doubt the effectiveness of PP405 based on press releases.
community [20M]What 8 months of no progress looks and feels like on fin/min/derma.
A 20-year-old has seen no improvement in hair loss after 8 months using finasteride, minoxidil, topical solutions, and microneedling. They express frustration and a loss of confidence due to the lack of results.
community 3 month min and microneedling update
A user shared a 3-month hair regrowth progress using minoxidil and microneedling. They also use rosemary oil and plan to continue treatment for at least 6-9 more months.