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GlossaryCannabinoid Receptor Type 2

protein involved in immune response and inflammation regulation

Cannabinoid Receptor Type 2 (CB2 receptor) is a protein found primarily in the immune system and peripheral tissues. It plays a crucial role in modulating inflammation and immune responses. Unlike its counterpart, the CB1 receptor, which is mainly located in the brain and central nervous system, CB2 receptors are less associated with psychoactive effects and are being studied for their potential therapeutic benefits in conditions like chronic pain, autoimmune diseases, and even hair growth disorders.

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Human Epithelial Stem Cell Survival Within Their Niche Requires Tonic Cannabinoid Receptor 1 Signaling—Lessons From the Hair Follicle

research Human Epithelial Stem Cell Survival Within Their Niche Requires Tonic Cannabinoid Receptor 1 Signaling—Lessons From the Hair Follicle

14 citations, February 2021 in “Experimental Dermatology”

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

research Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases

3 citations, December 2022 in “Cells”

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

research Cannabinoid Signaling in the Skin: Therapeutic Potential of the Cutaneous Cannabinoid System

142 citations, March 2019 in “Molecules/Molecules online/Molecules annual”

Cannabinoids may help treat various skin conditions.

research Unravelling a Novel Role for Cannabidivarin in the Modulation of Subventricular Zone Postnatal Neurogenesis

May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Cannabidivarin (CBDV) helps new brain cells grow and develop in a specific brain area through a certain receptor.

research Activation of Transient Receptor Potential Vanilloid-3 Inhibits Human Hair Growth

105 citations, May 2011 in “The journal of investigative dermatology/Journal of investigative dermatology”

Activating TRPV3 stops human hair growth.

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community My microneedling journey (no min, fin, etc)

in Microneedling 187 upvotes 1 month ago

The user experienced positive hair growth results using microneedling with rosemary and mint oil, without Minoxidil, Finasteride, or RU58841. They switched from a dermaroller to a microneedling pen and targeted different scalp areas weekly.

community JW Pharmaceutical shows superiority of 'JW0061' in hair growth over existing treatments in US

in Research/Science 99 upvotes 5 months ago

JW0061 shows superior hair growth results compared to existing treatments, with significant increases in hair follicles. The Wnt/β-catenin pathway is crucial for hair growth, and JW0061 activates this pathway effectively.

community About the CBD regrowth study : just a few remarks

in Research/Science 167 upvotes 3 years ago

CBD in an emu and lanolin oil preparation showed a 100% increase in hair growth, but the effectiveness may partly come from the oils. Users discussed proper CBD dosage, preparation methods, and skepticism about the study's quality.

community Hair Regrowth with Novel Hemp Extract - anyone seen this??

in Research/Science 18 upvotes 3 months ago

A user discusses a novel hemp extract for hair regrowth, which showed superior results to finasteride and minoxidil. The formula includes CBD, CBDV, THCV, delta 9 THC, cannabigerol, and cannabinol, combined with menthol, peppermint oil, ethanol, Emu oil, HFA 134A propellant, and dimethicone.