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research Expression patterns of the glial cell line–derived neurotrophic factor, neurturin, their cognate receptors GFRα-1, GFRα-2, and a common signal transduction element c-Ret in the human skin hair follicles

18 citations , January 2008 in “Journal of The American Academy of Dermatology”

This study found that the proteins GDNF, NTN, GFRα-1, GFRα-2, and c-Ret are differentially expressed during various stages of the human hair follicle cycle, with potential implications for hair biology.

research Pattern of expression of c-Myc, Max and Bin1 in human anagen hair follicles

11 citations , June 2001 in “British Journal of Dermatology”

This study found that asynchronous differentiation in human anagen hair follicles involves specific localization of c-Myc and interrelated genes Max and Bin1 along the inner root sheath.

research Co-Expression Pattern of Artemis Serine 516 Phosphorylation with Indicators Involving in Differentiation, Proliferation and Apoptosis of Human Anagen Hair Follicles: An Immunofluorescence Double-Staining Study

January 2023 in “Frontiers in bioscience”

This study suggests that Artemis, particularly phosphorylated at serine 516, may have roles in hair follicle growth by influencing differentiation, proliferation, apoptosis, and cell cycling.

research Patterns of epithelial expression of Fos protein suggest important role in the transition from viable to cornified cell during keratinization

83 citations , February 1991 in “Development”

This study found that Fos protein expression is closely linked to epithelial cell differentiation, particularly during cornification and cell death, with overexpression observed in keratinization-blocked mutant epidermis.

research Gene-wide association study between the aromatase gene (CYP19A1) and female pattern hair loss

77 citations , April 2009 in “British Journal of Dermatology”

In this study, genetic variation in the CYP19A1 gene, particularly the common rs4646 C allele, was associated with an increased risk of female pattern hair loss, especially in women under 40.

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Community Join

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community 3 Months on Topical DUT & MIN Female Pattern Baldness

4 upvotes 9 months ago

A user shared progress on treating female pattern baldness with a topical solution containing Minoxidil, Dutasteride, Tretinoin, Ketoconazole, and Hydrocortisone, along with supplements like Collagen Peptides, NAC, Vitamin C, and Keratin. Another user commented on the impressive results, noting the use of topical Dutasteride.

community Topical Vitamin C trials for hair loss?

in Treatment 6 upvotes 9 months ago

Topical high-dose vitamin C is discussed as a potential treatment for hair loss due to its ability to inhibit DHT and reduce histamine. Some users express skepticism about its effectiveness compared to treatments like finasteride.

community What hair loss pattern is this?

in General 157 upvotes 9 months ago

The user noticed small circular hairless spots after a buzz cut and has been using finasteride, dutasteride, and oral minoxidil for hair loss. They are experiencing continuous shedding and thinning, and it is suggested they consult a dermatologist for a scalp examination and possible biopsy to determine if it's alopecia areata or androgenetic alopecia.

community Is this a male pattern baldness or diffuse baldness?

in General 144 upvotes 2 years ago

A 23-year-old male experienced sudden hair loss over six months, losing about 30% of his hair. Treatments include 10% minoxidil, a hair spray, and a vitamin pill; opinions on the cause vary between normal hair loss due to deficiencies and male pattern baldness.

community I’m crashing out (female pattern hair loss)

40 upvotes 1 month ago

A woman experiencing female pattern hair loss has been using topical minoxidil and ketoconazole shampoo but is seeking further treatment options due to plateaued results. Suggestions include spironolactone, finasteride, dutasteride, and other treatments like PRP, while emphasizing the importance of consulting a dermatologist and conducting thorough medical evaluations.

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Learn

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learn Scalp Micropigmentation

What is Scalp Micropigmentation and how does it help people with visible hair loss? Scalp Micropigmentation creates the illusion of hair follicles on the scalp for visible hair loss.

learn Hair Transplant

Is a hair transplant permanent? Transplanted hair usually lasts long term, but it is not guaranteed and the hair around it can keep thinning, so the overall result can change with time.
How much does a hair transplant cost? Hair transplant costs typically range from $1,000 to $25,000 depending on various factors.
Is there an age limit for hair transplantation? There is no fixed age limit. Many surgeons are cautious under about 25, because the future pattern of loss is hard to predict.

learn Minoxidil

Vasodilator used on the scalp and, at low doses, as a tablet

learn C 13-15 alkane

learn Vitamin C

Is an itchy scalp linked to vitamin C? There is no evidence that an itchy scalp signals vitamin C deficiency, or that vitamin C treats patchy hair loss (alopecia areata). Patchy hair loss needs a doctor's diagnosis.

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