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GlossaryPhosphate Buffer

solution maintaining stable pH in biological experiments

A phosphate buffer, often referred to as phosphate-buffered saline (PBS), is a solution commonly used in biological research to maintain a stable pH environment. It consists of a mixture of sodium phosphate, sodium chloride, and sometimes potassium phosphate, which helps to mimic the ion concentration and osmolarity of the human body, making it ideal for experiments involving cells and tissues.

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research Determination of Free Chemical Potential for Finasteride Diffusion Through SDS Micelle Suggested as Alternative Living Membrane System

August 2022 in “International journal of membrane science and technology”

Finasteride diffuses spontaneously through SDS micelles, suggesting they can replace living cell membranes.

Determination of Finasteride and Its Metabolite in Urine by Dispersive Liquid-Liquid Microextraction Combined with Field-Enhanced Sample Stacking and Sweeping

research Determination of Finasteride and Its Metabolite in Urine by Dispersive Liquid-Liquid Microextraction Combined with Field-Enhanced Sample Stacking and Sweeping

6 citations, March 2018 in “Journal of Chromatography A”

New method accurately measures finasteride and M3 in urine, helping evaluate pharmacokinetics.

research Neurosteroids Are Endogenous Neuroprotectants in an Ex Vivo Glaucoma Model

31 citations, November 2014 in “Investigative Ophthalmology & Visual Science”

A natural steroid in the body may protect against eye damage in glaucoma.

Formulation of Sodium Valproate Nanospanlastics as a Promising Approach for Drug Repurposing in the Treatment of Androgenic Alopecia

research Formulation of Sodium Valproate Nanospanlastics as a Promising Approach for Drug Repurposing in the Treatment of Androgenic Alopecia

19 citations, September 2020 in “Pharmaceutics”

Sodium Valproate nanospanlastics could be a safe and effective treatment for Androgenic Alopecia, with fewer side effects than minoxidil.

research Metabolic Study of Androsta-1,4,6-Triene-3,17-Dione in Horses Using Liquid Chromatography/High Resolution Mass Spectrometry

17 citations, August 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.

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community What is “caffeine ointment” and does it really work ?

in Product 7 upvotes 1 year ago

Caffeine ointment was mentioned as being as effective as Minoxidil for hair loss treatment without the side effects. Caffeine is also found in some shampoos.

community Serum DHT levels variation on dutasteride

in Treatment 1 year ago

Serum DHT levels and their variations when using dutasteride for hair loss treatment.

community 5% Minoxidil after 4 months - started with twice a day but went down to once because I kept forgetting in the morning. Really happy with how it is going!

in Progress Pictures 438 upvotes 1 year ago

The conclusion of the conversation is that the user started using 5% Minoxidil for hair loss and is happy with the progress. They also mentioned being trans and coming off testosterone, which they believe will help prevent further hair loss. Some users suggested using finasteride as well.

community Progress: From June 2022 (7 months of min + fin) to now (1 year) — I’ve lost so much density in this period and I have no idea why. I was getting pretty good resultup until that point. Is there anything else I can try? I’ve tried min, fin, tretinoin, micro needling, and castor oil. I feel hopeless.

in Progress Pictures 10 upvotes 1 year ago

The user lost hair density after 7 months of using minoxidil and finasteride and is seeking advice on other treatments after trying tretinoin, microneedling, and castor oil. Suggestions include checking for scalp conditions like eczema or psoriasis, changing minoxidil brands, and questioning hair dryer use and finasteride dosage.

community One year after my hair transplant! 3633 FUE grafts

in Transplants 824 upvotes 2 years ago

User shares one-year hair transplant results with 3633 FUE grafts. Responses discuss improved appearance, hairline looking pluggy, and doctor's location in Ottawa, Canada.

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