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GlossaryBMP signaling

regulates growth and development of bones and tissues

BMP signaling, short for Bone Morphogenetic Protein signaling, is a biological pathway that involves proteins called BMPs. These proteins play a crucial role in regulating the growth, development, and repair of bones and other tissues. In the context of hair, BMP signaling is important for hair follicle development and cycling, influencing processes like hair growth and regeneration.

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Conditioned Media Obtained from Human Outer Root Sheath Follicular Keratinocyte Culture Activates Signalling Pathways That Contribute to Maintenance of Hair-Inducing Capacity and Increases Trichogenicity of Cultured Dermal Cells

research Conditioned Media Obtained from Human Outer Root Sheath Follicular Keratinocyte Culture Activates Signalling Pathways That Contribute to Maintenance of Hair-Inducing Capacity and Increases Trichogenicity of Cultured Dermal Cells

6 citations, July 2012 in “Experimental Dermatology”

The substance from human hair root cells can help maintain hair growth and make skin cells more capable of growing hair.

research Pyridoxine Regulates Hair Follicle Development via the PI3K/Akt, Wnt, and Notch Signalling Pathways in Rex Rabbits

10 citations, October 2021 in “Animal nutrition”

Vitamin B6 helps increase hair growth and density in rabbits by affecting certain cell signaling pathways.

Ishige Sinicola Extract Stimulates Osteoblast Proliferation and Differentiation via the Bone Morphogenetic Protein 2/Runt-Related Gene 2 Signaling Pathway

research Ishige Sinicola Extract Stimulates Osteoblast Proliferation and Differentiation via the Bone Morphogenetic Protein 2/Runt-Related Gene 2 Signaling Pathway

4 citations, May 2019 in “Zeitschrift für Naturforschung C”

Ishige sinicola extract helps bone-building cells grow and mature, which could aid in treating osteoporosis.

research A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells

31 citations, August 2021 in “Stem Cell Research & Therapy”

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

research Study of Gene Expression Alteration in Male Androgenetic Alopecia: Evidence of Predominant Molecular Signaling Pathways

27 citations, April 2017 in “British Journal of Dermatology”

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

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community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

in Research/Science 92 upvotes 2 years ago

The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

community TGF-Beta. Good or Bad? Help for treatment investment

in Treatment 13 upvotes 2 years ago

TGF-B affects hair growth, both causing stem cell division and death depending on amounts. Amplifica's treatment injects Scube3 to increase TGF-B for hair growth.

community 7 months évolution of finasteride / zinc / vitamin D/ minoxidil / microneedling treatment

in Finasteride/Dutasteride 573 upvotes 2 years ago

User experienced hair loss improvement after 7 months using finasteride, zinc, vitamin D, minoxidil, and microneedling. Others praised the progress and discussed the importance of zinc and vitamin D in hair health.