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GlossaryBMP signaling

regulates growth and development of bones and tissues

BMP signaling, short for Bone Morphogenetic Protein signaling, is a biological pathway that involves proteins called BMPs. These proteins play a crucial role in regulating the growth, development, and repair of bones and other tissues. In the context of hair, BMP signaling is important for hair follicle development and cycling, influencing processes like hair growth and regeneration.

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research Role of the bone morphogenetic protein signalling in skin carcinogenesis. Effect of transgenic overexpression of BMP antognist Noggin on skin tumour development; molecular mechanisms underlying tumour suppressive role of the BMP signalling in skin.

January 2009 in “Bradford Scholars (University of Bradford)”

BMP signaling helps prevent skin tumors by blocking cancer-promoting pathways.

Conditioned Media Obtained from Human Outer Root Sheath Follicular Keratinocyte Culture Activates Signalling Pathways That Contribute to Maintenance of Hair-Inducing Capacity and Increases Trichogenicity of Cultured Dermal Cells

research Conditioned Media Obtained from Human Outer Root Sheath Follicular Keratinocyte Culture Activates Signalling Pathways That Contribute to Maintenance of Hair-Inducing Capacity and Increases Trichogenicity of Cultured Dermal Cells

6 citations , July 2012 in “Experimental Dermatology”

The substance from human hair root cells can help maintain hair growth and make skin cells more capable of growing hair.

research Pyridoxine Regulates Hair Follicle Development via the PI3K/Akt, Wnt, and Notch Signalling Pathways in Rex Rabbits

10 citations , October 2021 in “Animal nutrition”

Vitamin B6 helps increase hair growth and density in rabbits by affecting certain cell signaling pathways.

Ishige Sinicola Extract Stimulates Osteoblast Proliferation and Differentiation via the Bone Morphogenetic Protein 2/Runt-Related Gene 2 Signaling Pathway

research Ishige Sinicola Extract Stimulates Osteoblast Proliferation and Differentiation via the Bone Morphogenetic Protein 2/Runt-Related Gene 2 Signaling Pathway

4 citations , May 2019 in “Zeitschrift für Naturforschung C”

Ishige sinicola extract helps bone-building cells grow and mature, which could aid in treating osteoporosis.

research A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells

31 citations , August 2021 in “Stem Cell Research & Therapy”

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

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community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

in Research/Science 92 upvotes 3 years ago

The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community GT20029 and PP405 the new fin and min that we been waiting for ?

in Chat 35 upvotes 4 months ago

PP405 and GT20029 are new hair loss treatments with different mechanisms from traditional options like Minoxidil and Finasteride. PP405 targets hair follicle stem cells to reactivate growth, while GT20029 works as an androgen receptor deleter, both requiring ongoing use for effectiveness.

community TGF-Beta. Good or Bad? Help for treatment investment

in Treatment 11 upvotes 3 years ago

TGF-B affects hair growth, both causing stem cell division and death depending on amounts. Amplifica's treatment injects Scube3 to increase TGF-B for hair growth.

community 7 months évolution of finasteride / zinc / vitamin D/ minoxidil / microneedling treatment

in Finasteride/Dutasteride 571 upvotes 3 years ago

User experienced hair loss improvement after 7 months using finasteride, zinc, vitamin D, minoxidil, and microneedling. Others praised the progress and discussed the importance of zinc and vitamin D in hair health.