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learn Biotin

B vitamin, often sold as a hair supplement

Biotin, Biotinyl-GHK, biotinoyl-tripeptide-1… are they not the same? Biotin is a vitamin. Biotinyl-GHK and biotinoyl tripeptide-1 are two names for the same cosmetic peptide (biotin attached to GHK), usually sold inside the Procapil complex.
Biotin: the darling of hair products. A 2017 review found that every published case of biotin helping hair was in a person with a biotin deficiency (which is rare) or another underlying condition, and no good evidence that it helps healthy people. The FDA warns that biotin can make some blood tests give wrong results.
Biotinyl-GHK: a miracle ingredient against hair loss? Biotinyl-GHK (biotinoyl tripeptide-1) is a cosmetic ingredient, not an approved hair-loss medicine; the published studies test it only inside multi-ingredient complexes such as Procapil, so no result can be attributed to the peptide itself.
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learn Folic acid

Can folic acid be combined with other treatments like minoxidil or biotin for better results? There is no published controlled trial of folic acid combined with minoxidil and biotin, so no synergy has been demonstrated; the vitamins have documented value only for correcting a diagnosed deficiency, and high doses of each carry known cautions.

Research

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research Phenotypic variation in biotinidase deficiency

184 citations , August 1983 in “The journal of pediatrics/The Journal of pediatrics”

In this study, biotinidase deficiency in children usually presented with neurological or skin symptoms, while metabolic ketoacidosis and organic aciduria appeared later.

research Biotin and biotinidase deficiency

166 citations , November 2008 in “Expert Review of Endocrinology & Metabolism”

This review discusses biotin and biotinidase deficiencies, their symptoms, and methods of medical management, without presenting new clinical findings.

research Uncombable hair syndrome: Observations on response to biotin and occurrence in siblings with ectodermal dysplasia

101 citations , July 1985 in “Journal of the American Academy of Dermatology”

In this study, oral biotin improved hair growth, strength, and combability in a child with uncombable hair syndrome, while hair in two others slowly improved without biotin.

research Biotinidase Deficiency: Prevalence, Impact And Management Strategies.

89 citations , January 2020 in “PubMed”

This review discusses biotinidase deficiency, noting that biotin treatment from birth can prevent symptoms, but acknowledges the complexity and need for further understanding due to late-onset cases with varied clinical findings.

research New aspects of galectin functionality in nuclei of cultured bone marrow stromal and epidermal cells: biotinylated galectins as tool to detect specific binding sites

89 citations , October 2003 in “Biology of the Cell”

This study found that labeled galectin-1 binds to specific nuclear sites in human bone marrow stromal cells and keratinocytes, suggesting a role in nuclear function, although only in a small fraction of cells.

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Community Join

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community What brand of Biotin works best for you guys that doesn’t break you out in cystic acne?

in General 93 upvotes 10 months ago

Biotin can cause cystic acne for some users, and it's advised to stop using it if this occurs. For hair loss, finasteride and dutasteride are recommended, but a dermatologist should be consulted.

community Biotin pills instead of biotin injections.

in Finasteride/Dutasteride 1 upvotes 1 year ago

Finasteride is recommended for hair loss, while biotin is considered ineffective and unnecessary. Minoxidil is also suggested, and biotin pills are preferred over injections due to cost and absorption concerns.

community How biotin benefited you? Could it strengthen hair?

in Product 6 upvotes 1 year ago

Biotin may strengthen existing hair and reduce hair loss, but it doesn't promote new hair growth. Some users report stronger, darker hair, while others see no benefits or experience acne.

community Is Biotin or Keratin shampoo better for hair health/growth

6 upvotes 2 years ago

Biotin and Keratin shampoos are discussed for hair health and growth. Users suggest shampoos alone don't significantly aid hair growth.

community Biotin/saw palmetto/pumpkin seed supplements and body fat

3 upvotes 5 years ago

The conversation discusses concerns about weight gain potentially linked to biotin, saw palmetto, and pumpkin seed supplements, with users generally doubting the supplements are the cause. One user stopped taking saw palmetto due to side effects but did not notice improved results.

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