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research From skin aging biomarkers to precision esthetic longevity: a translational diagnostic framework

August 2026 in “Frontiers in Medicine”

This article argues that esthetic dermatology could benefit from a more biologically informed approach through the integration of advanced biomarkers and imaging technologies, but cautions that many tools are not yet fully validated for clinical use.

research DNA Methylation‐Regulated ZDHHC17 Promotes the Risk of Facial Skin Aging

December 2025 in “Clinical Cosmetic and Investigational Dermatology”

This study highlights the potential of ZDHHC17 methylation as a biomarker or therapeutic target in addressing skin aging, offering new insights into its molecular mechanisms.

research Comprehensive RNA sequencing in primary murine keratinocytes and fibroblasts identifies novel biomarkers and provides potential therapeutic targets for skin-related diseases

17 citations , October 2021 in “Cellular & Molecular Biology Letters”

This study identified novel biomarkers through gene expression differences between keratinocytes and fibroblasts in newborn mice, which may aid in developing therapies for skin conditions.

research The Potential Application of Exosomes as Therapeutic Agents, Carriers, and Biomarkers in Skin Diseases

1 citations , October 2025 in “International Journal of Nanomedicine”

This review explores the potential for using exosomes in treating autoimmune skin diseases and promoting skin regeneration, highlighting current applications, delivery methods, and ongoing clinical trials while also identifying challenges and future research directions within dermatology.

research Metabolism and skin diseases

8 citations , September 2016 in “Reviews in Endocrine and Metabolic Disorders”

Skin health and diseases are closely linked to metabolic processes.

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community Minox 3mg, Finasteride 1.2mg (6 month perfect adherence)

370 upvotes 5 months ago

Significant hair improvement was achieved using 3mg Minoxidil and 1.2mg Finasteride over six months, with no side effects, leading to reconsideration of a hair transplant. A detailed skincare routine, including tretinoin and SPF, also improved skin appearance.

community Bruteforcing alopecia or the new advent of science progress

22 upvotes 1 year ago

Combining therapies like scyllo-inositol, alpha-ketoglutarate, and autophagy-inducing supplements may enhance hair growth and prevent hair loss. Reporting individual results can accelerate progress in hair loss treatments.

community Solving Hair Loss with Research at MIT

in Research/Science 595 upvotes 1 year ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

community Efficacy of Dut at 0.5mg VS 1mg VS 2.5mg

in Finasteride/Dutasteride 49 upvotes 1 year ago

Higher doses of dutasteride, such as 2.5mg, are more effective at reducing scalp DHT than 0.5mg, but are costly and inconvenient. A 1mg dose is considered a more affordable and practical option, though its efficacy is uncertain.

community Dutasteride at 21 years old. Is it safe?

in Finasteride/Dutasteride 12 upvotes 2 years ago

A 21-year-old individual questioning the safety and potential side effects of using Dutasteride for hair loss, after Finasteride and RU58841 had limited effect. The responses vary, with some users suggesting it's safe and others advising to check hormone levels before proceeding.

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Noelle Skin
Nice, France

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Noelle Skin