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Glossary Binding Proteins

molecules that attach to specific substances for transport or regulation

Binding proteins are molecules that attach to specific substances, such as hormones, nutrients, or DNA, to help transport, stabilize, or regulate them within the body. For example, in the context of hair biology, certain binding proteins might interact with hormones like androgens, influencing hair growth and potentially playing a role in conditions like alopecia.

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Research

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research Estrogen regulates the expression of retinoic acid synthesis enzymes and binding proteins in mouse skin

3 citations , August 2021 in “Nutrition research”

This study suggests that estrogen regulates vitamin A metabolism in skin tissues in a sex-dependent manner, which may have implications for treating acne, hair loss, and skin immunity.

research [Analysis of steroids and binding proteins in the blood of women with androgenetic alopecia].

July 1994 in “PubMed”

In this study, Diane treatment in women with androgenetic alopecia led to normalization of hormone levels and improved hair condition, including less greasiness and reduced hair loss.

Expression of Calcium-Binding S100 Proteins A4 and A6 in Regions of the Epithelial Sac Associated with the Onset of Hair Follicle Regeneration

research Expression of Calcium-Binding S100 Proteins A4 and A6 in Regions of the Epithelial Sac Associated with the Onset of Hair Follicle Regeneration

72 citations , June 2001 in “Journal of Investigative Dermatology”

This study suggests that S100A4 and S100A6 proteins may play key roles in activating stem cells for hair follicle regeneration in mice.

research Function and interactions of the Ysc84/SH3yl1 family of actin- and lipid-binding proteins

6 citations , January 2015 in “Biochemical Society Transactions”

This review discusses the role of Ysc84/SH3yl1 proteins in linking actin regulation to membrane morphology changes but reports no new experimental results.

research The structure of human trichohyalin. Potential multiple roles as a functional EF-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein

161 citations , June 1993 in “Journal of Biological Chemistry”

This study suggests that human trichohyalin may function as a flexible rod linking keratin intermediate filaments and as a scaffold protein in hair follicle and epidermis cell envelopes.

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Community Join

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community Cold and Japanese researchers. The Japanese began to suspect something. But they understood the mechanism to some extent. ( Cold shock therapy promotes hair growth in association with upregulation of cold-inducible RNA-binding protein and vascular endothelial growth factor).

36 upvotes 1 year ago

Cold shock therapy may promote hair growth, but cold alone is not effective. Combining treatments like minoxidil, finasteride, cold showers, spicy foods, and exercise may enhance results.

community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 1 year ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

community Minoxidil + Gym + Cutting. Is it bad?

37 upvotes 3 years ago

A user is concerned about weight loss stagnation while using minoxidil and finasteride during a calorie-cutting diet. Responses suggest water retention or a weight loss plateau as possible causes.

community isoflavones to combat gyno?

4 upvotes 6 years ago

Isoflavones from soybeans may help limit estrogen's effects on the body, potentially preventing gyno. However, surgery is the only way to remove gland enlargement.

community IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia

in Research/Science 13 upvotes 1 year ago

IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Stem Cell Factor

learn sh-Polypeptide-7

learn Epidermal Growth Factor

learn Beta Polypeptide

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