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research New topical antiandrogenic formulations can stimulate hair growth in human bald scalp grafted onto mice

37 citations , January 2000 in “International Journal of Pharmaceutics”

In a study using human scalp skin grafts on SCID mice, topical flutamide and finasteride significantly improved hair growth in male-pattern baldness compared to placebo, with flutamide showing superior results to finasteride.

research In vivohair growth-stimulating effect of medicinal plant extract on BALB/c nude mice

15 citations , January 2015 in “Pharmaceutical Biology”

In a study on nude mice, topical application of Chrysanthemum zawadskii extracts stimulated hair growth and increased hair follicle numbers, suggesting potential for alopecia therapy.

Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia

research Faculty Opinions recommendation of Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia.

January 2016 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

A substance called prostaglandin D2 is found more in bald scalps and it stops hair from growing. Blocking its receptor could potentially treat hair loss.

research Faculty Opinions recommendation of Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia.

May 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Prostaglandin D2, found in higher levels in bald scalps, stops hair growth, suggesting that blocking its receptor could potentially treat hair loss.

research The Pathogenesis of Alopecia Areata in Rodent Models

23 citations , June 2003 in “Journal of Investigative Dermatology Symposium Proceedings”

This review discusses rodent models of alopecia areata and suggests they are crucial for understanding the autoimmune mechanisms and potential treatments but reports no new clinical results.

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Community Join

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community Natural sweetener Stevia found to turbocharge male pattern baldness treatment: Mice given Stevia patch had 18 times better absorption of minoxidil and hair coverage of 67.5% in bald areas after just 35 days.

1741 upvotes 8 months ago

Stevia microneedles increased minoxidil absorption and hair growth in mice. The conversation humorously questions the applicability of these results to humans.

community New study suggests hair regrowth on wounded and bald skin may be possible

4 upvotes 7 years ago

Hair regrowth on wounded and bald skin may be possible by activating the sonic hedgehog gene, leading to hair regrowth in mice. The findings are promising but may not directly apply to humans.

community Bhringraj oil (an ayurvedic medicinal oil) worked better than minoxidil in this experiment on mice for hair regrowth

17 upvotes 7 years ago

Bhringraj oil showed better hair regrowth results than minoxidil in mice, but its effectiveness in humans is uncertain. Users discussed using bhringraj oil, coconut oil, and microneedling for hair regrowth, with some reporting slow but noticeable improvements.

community Woolly mice but no hair growth treatment for humans yet 🤷‍♂️

in Technology 225 upvotes 1 year ago

Hair regrowth treatments are effective in mice but not yet available for humans. The discussion humorously highlights frustration over this disparity and mentions a project to genetically modify elephants to resemble mammoths.

community Why do the mice always win????

25 upvotes 1 year ago

A new stem cell therapy shows promise in treating hair loss, but skepticism remains about its availability. Users humorously discuss the effectiveness of treatments on mice compared to humans.

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Learn

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learn Overview

learn Aloe vera

Are random bald spots stressing you out? Aloe vera gel might be your scalp’s natural first aid. Aloe vera gel may help soothe and support scalp health for random bald spots.

learn Centella

Got small bald circles with no warning? Centella creams might calm the area and kickstart new growth. There is no published human trial of Centella asiatica for alopecia areata or any other hair loss; the only hair-related studies are cell-culture work. Community users describe Centella creams as soothing for an irritated scalp, not as regrowth treatments, and a new bald patch needs a doctor's diagnosis first.

learn PP405

Got small bald patches they say are from stress? PP405 sprays could help bring them back to life. PP405 is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier; its registered Phase 2 trial (NCT06393452) tested it once daily in 78 adults with pattern hair loss, for safety and tolerability. It is not approved, not for sale, and has not been studied in alopecia areata or stress-related shedding.

learn Hair Transplant

Can you go bald after a hair transplant? Yes, you can still go bald after a hair transplant due to thinning native hair.

learn procapil

Tried everything and still getting bald patches? Procapil may help calm the immune response Procapil is a cosmetic ingredient complex; laboratory studies of its individual ingredients report anti-inflammatory effects, but no published clinical trial has tested it in alopecia areata or any other immune-related hair loss. Spreading bald patches should be assessed by a dermatologist.

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Clinics

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Experts

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48
Hair Loss Specialist
Kelsie Baldé
Pittsburgh, PA, United States

Kelsie Baldé