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Research

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research The Long-Term Effect of Doxazosin, Finasteride, and Combination Therapy on the Clinical Progression of Benign Prostatic Hyperplasia

1707 citations , December 2003 in “The New England Journal of Medicine”

Combination therapy of doxazosin and finasteride safely and effectively reduces benign prostatic hyperplasia progression risk.

research Evidence based medicine: a movement in crisis?

1647 citations , June 2014 in “BMJ”

This article argues that while evidence-based medicine has provided many benefits, it has also led to negative unintended consequences, and proposes a renewed focus on integrating context and professional expertise to improve patient treatment.

research The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed

1308 citations , March 1998 in “Journal of bone and mineral research”

This review discusses the molecular role of the vitamin D receptor in regulating various biological actions such as bone mineralization and reports no new clinical results, highlighting the complexity of vitamin D's function in multiple tissues.

research The Biology of Hair Follicles

1113 citations , August 1999 in “The New England Journal of Medicine”

This article discusses the biologic and psychosocial significance of hair, the current limitations in hair growth drugs, and anticipates future therapies based on advancing hair follicle research.

research The Nuts and Bolts of Low-level Laser (Light) Therapy

1057 citations , November 2011 in “Annals of Biomedical Engineering”

This review discusses the applications of low level laser therapy (LLLT) in wound healing, pain reduction, and treating various conditions, but reports no new clinical results; the authors highlight the need for randomized controlled trials for serious diseases.

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Community Join

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community Have b-complex vitamins helped anyone else?

4 upvotes 2 years ago

B-complex vitamins may improve hair appearance but have limited impact on hair loss. Some users also use minoxidil and finasteride for hair loss treatment.

community Hair Transplant Recommendations Within $3000 Budget

in Basic Questions 46 upvotes 1 month ago

The user is seeking recommendations for countries to get a hair transplant with a budget of £3000. They are considering treatments like Minoxidil, finasteride, and RU58841.

community How many grafts do I need for a natural hairline and fuller temples? £3,800–£4,000 total budget

in Basic Questions 121 upvotes 2 months ago

The user is planning a hair transplant with a budget of £3,800–£4,000 and is considering 2,500–2,700 grafts for a natural hairline and fuller temples. They have been using finasteride and minoxidil for a year and are seeking recommendations for surgeons or clinics in affordable European destinations.

community Best supplements to compliment finasteride protocol

17 upvotes 2 months ago

The conversation discusses supplementing a finasteride regimen for hair loss with Omega 3, Vitamin D/K, Zinc, probiotics, and possibly adding oral minoxidil, magnesium, astaxanthin, and B vitamins. Users suggest testing nutrient levels before adding supplements like zinc and iron, and consider biotin, keratin, and possibly switching to dutasteride or adding topical minoxidil.

community Is it time for a Hair Transplant based on the thinning/balding in my crown

in Basic Questions 58 upvotes 2 months ago

The user is considering switching from liquid to foam minoxidil for hair loss at the crown, while already using finasteride pills. They are also contemplating a hair transplant due to ongoing hair thinning.

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Learn

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learn Biotin

B vitamin, often sold as a hair supplement

Biotin, Biotinyl-GHK, biotinoyl-tripeptide-1… are they not the same? Biotin is a vitamin. Biotinyl-GHK and biotinoyl tripeptide-1 are two names for the same cosmetic peptide (biotin attached to GHK), usually sold inside the Procapil complex.
Biotin: the darling of hair products. A 2017 review found that every published case of biotin helping hair was in a person with a biotin deficiency (which is rare) or another underlying condition, and no good evidence that it helps healthy people. The FDA warns that biotin can make some blood tests give wrong results.
Biotinyl-GHK: a miracle ingredient against hair loss? Biotinyl-GHK (biotinoyl tripeptide-1) is a cosmetic ingredient, not an approved hair-loss medicine; the published studies test it only inside multi-ingredient complexes such as Procapil, so no result can be attributed to the peptide itself.
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learn Baricitinib

JAK inhibitor pill used for severe alopecia areata

learn Beta Polypeptide

learn Bicalutamide

Nonsteroidal anti-androgen, originally a prostate cancer drug

learn Bimatoprost

Prostaglandin eye drop used for glaucoma and eyelash growth

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