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research 'Atrophic telogen effluvium' from cytotoxic drugs and a randomized controlled trial to investigate the possible protective effect of pretreatment with a topical vitamin D3 analogue in humans

47 citations , July 2005 in “British Journal of Dermatology”

This study found no protective effect of topical calcipotriol on hair loss in chemotherapy patients, and the authors propose the term "atrophic telogen effluvium" for this type of hair loss.

research Serial sections of atrophic acne scars help in the interpretation of microscopic findings and the selection of good therapeutic modalities

36 citations , November 2011 in “Journal of the European Academy of Dermatology and Venereology”

This study identified distinct microscopic characteristics of acne scars, including inflammatory infiltrates and insufficient collagen deposition, suggesting that treatment should consider these histopathological findings and employ combination therapy.

research PSEUDOPELADE: AN INHERITED ALOPECIA

19 citations , October 1996 in “International Journal of Dermatology”

This study concluded that pseudopelade is an autosomal dominant condition, distinct from other forms of alopecia, characterized by atrophic hair follicle loss and notable familial association.

research Erosive Pustular Dermatosis of the Scalp

September 2021 in “CRC Press eBooks”

This review discusses erosive pustular dermatosis of the scalp, including its characteristics, potential triggers, and its classification as a neutrophilic dermatosis, but reports no new clinical findings.

research Distinctive histopathologic findings in linear morphea (en coup de sabre) alopecia

19 citations , March 2013 in “Journal of Cutaneous Pathology”

This case report describes a 26-year-old female with linear morphea and unique alopecia characterized by atrophic follicular remnants, resembling telogen follicles but indicating permanent alopecia, unlike typical findings in morphea-related alopecia.

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community Anyone here have a lot of knowledge on hair follicle stem cells and progenitor cells for PP405?

in Chat 4 upvotes 8 months ago

Hair follicle stem cells remain in bald individuals, but progenitor cells do not, raising questions about hair regrowth claims by Pelage. PP405 is discussed as a potential treatment, with skepticism about its effectiveness compared to existing treatments like Minoxidil and Finasteride.

community Microneedling must reach the stem cells in the upper hair shaft

82 upvotes 4 years ago

Microneedling should target depths of 0.5mm to 1.5mm for hair loss, with weekly sessions at 1mm recommended. Combining microneedling with Minoxidil is common for improved results.

community Pyrilutamide (KX-826) personal consideration

in Research/Science 1 upvotes 1 year ago

Pyrilutamide (KX-826) is discussed as an anti-androgen treatment for hair loss, with mixed user experiences. Some users report no results, while others find it mildly effective.

community Long term finasteride users; Did you notice any improvement after 2 years?

in Finasteride/Dutasteride 14 upvotes 3 years ago

Long term Finasteride users and whether or not they have noticed improvements after two years of use, with other treatments such as Minoxidil and dermarolling also discussed. Some replies suggest that improvement is possible even beyond the two year mark while others caution against believing studies backed by the Post-Finasteride Foundation.

community AGA/male pattern baldness and loss of hair in the past 6months

52 upvotes 8 months ago

A 25-year-old male experienced significant hair loss due to telogen effluvium and androgenetic alopecia. He began using finasteride, minoxidil, and vitamins, seeing some regrowth but remains worried about hair density.

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Clinics

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learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Folic acid

How does folic acid support hair follicle health and growth at a cellular level? Folate is required for the DNA synthesis that fast-dividing hair matrix cells depend on, and severe deficiency causes anemia—but no published trial has given folic acid to people with hair loss and measured the result, so a growth effect is a mechanism, not a finding.

learn Hair Transplant

Surgery that moves hair follicles from the back of the scalp to thinning areas

What is shock loss? Shock loss is shedding of existing hairs near the grafts or in the donor area after surgery. It usually regrows within a few months, but hairs that were already thinning may not come back.

learn Finasteride

Does hair strand thickness decrease in men with androgenic alopecia? Can finasteride help restore it? Androgenic alopecia thins hair strands by miniaturizing follicles. The pivotal finasteride trials (1,553 men, 1 mg/day, two years) report increased hair counts and improved assessed appearance, but they measured density, not the diameter of individual strands, so the effect on thickness itself is not established.

learn zinc PCA

Can a zinc deficiency directly cause hair thinning or increased shedding? Studies link low serum zinc to diffuse shedding and alopecia areata, and severe deficiency states cause hair loss that reverses when zinc is replaced. The evidence is mostly observational, the one supplementation study was small and uncontrolled, and zinc is not a treatment for pattern hair loss.

learn TDM-105795

What types of alopecia or hair loss conditions might TDM-105795 be designed to target based on current research? TDM-105795 has been studied only in men with androgenetic alopecia, in two Phase 1 studies and one 16-week Phase 2 trial. There is no research on it in women or in any other type of hair loss.

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Experts

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SMP Specialist
Hairo Fallas
Newark, NJ, United States

Hairo Fallas