1 citations
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September 2020 in “Pediatric Dermatology” In this case report, two adolescents developed androgenetic alopecia after treatment with anastrozole for idiopathic short stature, suggesting this potential side effect should be considered in pediatric patients using aromatase inhibitors.
77 citations
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April 2009 in “British Journal of Dermatology” In this study, genetic variation in the CYP19A1 gene, particularly the common rs4646 C allele, was associated with an increased risk of female pattern hair loss, especially in women under 40.
February 2026 in “Revista Eletrônica Polidisciplinar Voos.” In this integrative narrative review, researchers reported that aromatase inhibition using dutasteride and Serenoa repens after hair transplant can effectively preserve follicles and minimize side effects, suggesting personalized strategies may optimize clinical outcomes and patient satisfaction.
65 citations
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May 2006 in “Journal of Investigative Dermatology” This study found that dexamethasone significantly reduced ERα mRNA levels and increased aromatase mRNA and activity in cultured human hair follicle dermal papilla cells, suggesting a glucocorticoid-dependent mechanism for estradiol action.
36 citations
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October 2016 in “Bone” This case report describes a male patient with aromatase deficiency, revealing that a c.628G>A mutation can lead to varied clinical features, such as low bone mass and normal metabolic profiles.