June 2008 in “Experimental dermatology” This research found that melatonin plays a protective and modulatory role in skin biology, reducing UV damage and chemotherapy-induced hair follicle cell harm in human organ culture models.
26 citations
,
March 2018 in “Dermatology and Therapy” This study found that conditioned media from epidermal progenitor cells improved skin aging signs in a clinical trial and protected fibroblasts from oxidative stress in vitro.
14 citations
,
October 2020 in “Journal of ethnopharmacology” This study found that both ethanol and aqueous extracts of Lepidium sativum seeds improved insulin signaling and reduced obesity-related metabolic changes in high-fat diet-fed rats, suggesting potential as a dietary supplement.
5 citations
,
May 2024 in “Molecules” This study found that glycyrrhetinic acid, derived from licorice, may help alleviate acne symptoms by regulating lipid synthesis and inflammatory responses through multiple pathways, as observed in both in vitro and in vivo settings.
32 citations
,
January 2022 in “International Journal of Molecular Sciences” This review discusses the impact of melatonin and its metabolites on skin aging, summarizing how they may serve as "aging neutralizers" through their anti-oxidative and anti-inflammatory properties, but reports no new clinical results.
